Agni - Key factor for Shodhananga Snehapana

Agni is termed as Vaishwanara as it takes the person from Mruthyuloka to Swargaloka. It is an important factor and is equitant to Prana; is one among Dashaprana Ayatana. Agni in Shareera is present in different forms with different actions. It is the responsible factor for both health and disease; on the other hand the successful outcome of treatment is also dependant on Agni. Chikitsa (treatment) is the process of bestowing normalcy which is either brought by Shodhana (purificatory) or Shamana (palliative) Karma. Snehapana is a pre-operative procedure for Shodhana Chikitsa where in Sneha Dravya (medicated fat) is administered for attainment of Upasthita Dosha Avastha and further ease in elimination of the vitiated Doshas. Assessment of Dosha, Dushya, Vyadhi Avastha, Roga Bala, Rogi Bala, Agni, Koshta etc. factors are essential for the attainment of Chikitsa Phala. Assessment of Agni not only helps in understanding Vyadhi but also enables to plan the dosage of Sneha to be administered. Thus this paper is an attempt to throw light on the importance of Agni, assessment of Agni and Agni Bala prior to Shodhananga Snehapana

Cranio-Cerebral Injuries in Victims of Fatal Road Traffic Accident: A 5 year Post-Mortem Study

Background:Victims of vehicular accident sustain different types of injuries, of which, head injury is considered as more fatal than injury to other systems. This study was carried out to know the incidence and pattern of cranio-cerebral injuries in victims of fatal vehicular accidents.Methods: Medico-legal autopsies conducted on victims of vehicular accidents from 01-01-2008 to 31-12-2012 at the Dept. of Forensic Medicine, Father Muller Medical College, Mangalore, Karnataka, India, were retrospectively analysed.Results:Deaths due to vehicular accidents constituted 69% of the total unnatural deaths. Cranio-cerebral injuries were present in 68.5% of victims of vehicular accident. Combination of skull fracture, intra-cranial haemorrhages and cerebral injury was seen in maximum number of victims (38.2%). If injuries are considered individually, most commonly observed injury was intracranial haemorrhage (90.7%), followed by skull fracture (78.9%). Subarachnoid haemorrhage was the commonest type of intracranial haemorrhage present (78.3%). In the skull vault, linear fracture was the commonest type (49%) and in the base, middle cranial fossa (68.3%) was the most commonly fractured fossa. Among the cerebral injuries, contusion of the brain tissue was the commonest injury seen. Frontal and temporal lobes were the most commonly injured parts of the cerebrum (65.8%).Conclusion:Most of the cranio-cerebral injuries cannot be treated successfully because of their anatomical configuration. But, morbidity and mortality due to vehicular accidents can be reduced by preventing the occurrence of accidents. Therefore, the old saying, “Prevention is better than cure” holds good even here

Oral Proliferative Verrucous Leukoplakia-A Case Report

Oral Proliferative verrucous leukoplakia (OPVL), an aggressive and rare form of leukoplakia, is a long term progressive condition which in the initial stages starts as a harmless benign lesion. Eventually it may progress over a period of time to become multifocal, exophytic and malignant. This stumper of a disease, ambiguous in etiology, diagnosis and management poses a challenge to the clinician and the pathologist. This lesion is refractory to treatment and more often than not, recurs. In this article, we describe a case that possibly may have represented an OPVL

EFFECT OF FEEDING WITH MIXTURE OF COLOURD RICE ON SERUM LIPID PROFILE AND ANTIOXIDANT STATUS IN EXPERIMENTAL RATS

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Experimental and Numerical Study on Vibration-Based Damage Detection and Localization in Laminated Composite Plates

Damage detection in composite materials is crucial for ensuring the safety and reliability of engineering structures. Conventional methods often face challenges in accurately identifying damage in plate-like structures, particularly in scenarios involving multiple damages or small-scale delamination. This study focuses on investigating the detection and localization of delamination in composite plates by employing both experimental and numerical modal analysis. An eight-ply woven Glass-Epoxy composite laminate with and without damage was prepared with the aid of hand lamination technique. Laminate was fixed to a Clamped-Free-Free-Free (CFFF) boundary condition for experimental modal analysis by introducing controlled damage to examine its impact on modal properties. To validate the natural frequencies (NFs) of damaged and undamaged composite laminates, a numerical analysis was conducted using ANSYS Parametric Design Language (APDL). Further, to advance the understanding of using modal shapes and their spatial derivatives for damage localization in composite plates under various damage situations, post-processing of simulation results was conducted using MATLAB. Finite Difference Method has been employed to calculate the derivatives, and a novel damage index (DI) is proposed to enhance damage localization capabilities. The results affirm that the proposed DI is effective and precise in identifying damage in plate-like structures, both for individual and multiple damage scenarios. This research study presents a novel approach for identifying and pinpointing damage in composite plates, thereby making a valuable contribution to the field of structural health monitoring (SHM) application

Myxoma of mandible – A case report with literature review

The odontogenic myxoma is an infiltrative benign tumor of bone that occurs almost exclusively in the jawbones and comprises 3% to 6% of odontogenic tumors. This neoplasm is mesenchymal and the myxomatous component is gelatinous in nature. Odontogenic epithelium may occur occasionally in the stroma. Although benign the odontogenic myxoma can cause considerable local destruction. An odontogenic myxoma occuring in the anterior mandible of an 18 year old male is reported here with literature review

A hybrid approach based on personality traits for hate speech detection in Arabic social media

In recent years, as social media has grown in popularity, people have gained the ability to freely share their views. However, this may lead to users' conflict and hostility, resulting in unattractive online environments. Hate speech relates to using expressions or phrases that are violent, offensive, or insulting to a minority of people. The number of Arab social media users is quickly rising, and this is being followed by an increase in the frequency of cyber hate speech in the area. Therefore, the automated detection of Arabic hate speech has become a major concern for many stakeholders. The intersection of personality learning and hate speech detection is a relatively less studied niche. We suggest a novel approach that is focused on extracting personality trait features and using these features to detect Arabic hate speech. The experimental results show that the proposed approach is superior in terms of the macro-F1 score by achieving 82.3% compared to previous work reported in the literature

High performance liquid chromatography for simultaneous determination of xipamide, triamterene and hydrochlorothiazide in bulk drug samples and dosage forms

A novel, simple and robust high-performance liquid chromatography (HPLC) method was developed and validated for simultaneous determination of xipamide (XIP), triamterene (TRI) and hydrochlorothiazide (HCT) in their bulk powders and dosage forms. Chromatographic separation was carried out in less than two minutes. The separation was performed on a RP C-18 stationary phase with an isocratic elution system consisting of 0.03 mol L–1orthophosphoric acid (pH 2.3) and acetonitrile (ACN) as the mobile phase in the ratio of 50:50 at 2.0 mL min–1 flow rate at room temperature. Detection was performed at 220 nm. Validation was performed concerning system suitability, limits of detection and quantitation, accuracy, precision, linearity and robustness. Calibration curves were rectilinear over the range of 0.195–100 µg mL–1 for all the drugs studied. Recovery values were 99.9, 99.6 and 99.0 % for XIP, TRI and HCT, respectively. The method was applied to simultaneous determination of the studied analytes in their pharmaceutical dosage forms

Bacterial contamination of white coats and hands of healthcare workers at mansoura university children’s hospital, Mansoura-Egypt

Background: Transmission of hospital acquired infections (HAIs) may be associated with contamination of healthcare workers’ (HCWs) hands and white coats.Objective: The purpose of this study was to clarify the role of HCWs’ white coats in transmitting HAIs and to determine the association between bacterial contamination of HCWs’ hands and white coats.Methods: A total of 154 HCWs were enrolled in the study; different samples were taken from their hands and white coats. Samples were processed and both microbiological and biochemical characterization of the isolates were done using standard microbiological protocols.Results: Up to 65.6% of hands and 61% of coats of HCWs were contaminated by microorganisms. Staphylococcus aureus was the most commonly isolated organisms from both hands and coats of HCWs (29.2%, 27.3% respectively) followed by MRSA (22.1%, 24.7% respectively).Conclusions: The risk for contamination of hands and coats of HCWs is high in different clinical settings. In order to reduce the rate of HAIs, a strict dress protocol should be set into play to prevent cross contamination between HCWs and patients.Keywords: contamination, HCWs, coat, hand, Staphylococcus aureus, MRSA. Contamination bacterienne de manteaux blancs et de mains de soins de sante a l'hopital pour enfants de l'universite mansoura, Mansoura-EgypteContexte: La transmission des infectionsObjectif: Le but de cette étude était de déterminer l'étendue, le type et l'association entre la contamination bactérienne des mains des travailleurs de la santé et les blouses blanches.Méthodes: Au total, 154 travailleurs de la santé ont été inclus dans l'étude; différents échantillons ont été pris de leurs mains et des manteaux blancs. Les échantillons ont été traités et la caractérisation microbiologique et biochimique des isolats a été effectuée en utilisant des protocoles microbiologiques standard.Résultats: Jusqu'à 65,6% des mains et 61% des couches de TS ont été contaminées par des micro-organismes. Le Staphylococcus aureus était le plus souvent isolé des deux mains et des deux sexes (29,2%, 27,3%), suivi par le SARM (22,1%, 24,7% respectivement).Conclusions: Le risque de contamination des mains et des couches de TS est élevé dans différents contextes cliniques. Afin de réduire le taux d'IASS, un protocole vestimentaire strict devrait être mis en place pour prévenir la contamination croisée entre les travailleurs de la santé et les patients.Mots clés: contamination, agents de santé, manteau, main, Staphylococcus aureus, SAR