Gaining Compliance and Losing Weight: The Role Of the Service Provider In Health Care Services

This research provides and empirically tests a conceptualization of health care services in which customer compliance outside of the service organization is necessary for successful health outcomes. Using data from service providers and customers in a weight-loss clinic, the authors examine the provider\u27s role in gaining customer compliance. They find that provider expertise and attitudinal homophily play a role in bringing about customer role clarity, ability, and motivation. This study demonstrates that compliance leads to goal attainment, which results in satisfaction. More important, compliance also leads to satisfaction directly; consumers who comply with program requirements have greater satisfaction with the program

The Cognitive Processes Underlying Affective Decision-Making Predicting Adolescent Smoking Behaviors in a Longitudinal Study

This study investigates the relationship between three different cognitive processes underlying the Iowa Gambling Task (IGT) and adolescent smoking behaviors in a longitudinal study. We conducted a longitudinal study of 181 Chinese adolescents in Chengdu City, China. The participants were followed from 10th to 11th grade. When they were in the 10th grade (Time 1), we tested these adolescents’ decision-making using the IGT and working memory capacity using the Self-ordered Pointing Test (SOPT). Self-report questionnaires were used to assess school academic performance and smoking behaviors. The same questionnaires were completed again at the 1-year follow-up (Time 2). The Expectancy-Valence (EV) Model was applied to distill the IGT performance into three different underlying psychological components: (i) a motivational component which indicates the subjective weight the adolescents assign to gains vs. losses; (ii) a learning-rate component which indicates the sensitivity to recent outcomes vs. past experiences; and (iii) a response component which indicates how consistent the adolescents are between learning and responding. The subjective weight to gains vs. losses at Time 1 significantly predicted current smokers and current smoking levels at Time 2, controlling for demographic variables and baseline smoking behaviors. Therefore, by decomposing the IGT into three different psychological components, we found that the motivational process of weight gain vs. losses may serve as a neuropsychological marker to predict adolescent smoking behaviors in a general youth population

Origins of Hidden Sector Dark Matter I: Cosmology

We present a systematic cosmological study of a universe in which the visible sector is coupled, albeit very weakly, to a hidden sector comprised of its own set of particles and interactions. Assuming that dark matter (DM) resides in the hidden sector and is charged under a stabilizing symmetry shared by both sectors, we determine all possible origins of weak-scale DM allowed within this broad framework. We show that DM can arise only through a handful of mechanisms, lending particular focus to Freeze-Out and Decay and Freeze-In, as well as their variations involving late time re-annihilations of DM and DM particle anti-particle asymmetries. Much like standard Freeze-Out, where the abundance of DM depends only on the annihilation cross-section of the DM particle, these mechanisms depend only on a very small subset of physical parameters, many of which may be measured directly at the LHC. In particular, we show that each DM production mechanism is associated with a distinctive window in lifetimes and cross-sections for particles which may be produced in the near future. We evaluate prospects for employing the LHC to definitively reconstruct the origin of DM in a companion paper.Comment: 32 pages, 19 figures; v2: references added, published versio

A Preliminary Report on Biosystematic Studies of Iowa Smartweeds (Polygonum Spp.)

The senior author first developed an interest in the smartweeds (Polygonum spp.) in connection with studies and survey work on the European corn borer (Pyrausta nubilalis Hubn.) and related borers. These are Pyrausta ainsliei Hein, the smartweed borer, and P. penitalis Grote, the lotus borer; both are native to North America, while P. nubilalis was introduced into this country from Europe and has become a serious pest of corn. This insect was first noticed in the United States in 1917 in the New England states. It gradually spread westward and was first reported in Iowa in 1943 from Clinton County. By last year (1947) it had spread throughout the state arid into eastern Nebraska

Ressources cognitives et développement territorial : une analyse textuelle appliquée aux politiques locales de développement durable

International audienceThis paper focuses on how the development of a particular region consistently requires actors to share a certain level of cognitive resources. In the case studied here - the Nord Pas-de-Calais region, this cognitive proximity is built via the local policies involving sustainable development. In order to comprehend the way local communities of the region activate this resource, we used textual data treatment analyzing about thirty interviews. The results suggest that this cognitive proximity relies on two fundamentals elements: on the one hand, valuing the patrimonial infrastructures of the territory; and on the other hand, rebuilding the territorial identity of the region. Then the local policies lean both on the values that underlie these elements and on rhetorical modalities, to impulse in-depth changes that would have been more difficult to implement from the usual political levers.Cet article étudie comment un développement régional cohérent nécessite la mobilisation de ressources cognitives partagées. Dans le cas étudié - la région Nord Pas-de-Calais, cette proximité cognitive se construit via les politiques locales, sur la base du référentiel de développement durable. Pour saisir la manière dont les collectivités de la région activent cette ressource, nous avons mobilisé les outils d'analyse textuelle sur une trentaine d'entretiens auprès des acteurs publics du développement durabe. Les résultats mis en évidence suggèrent que cette proximité cognitive repose sur deux éléments fondamentaux : d'une part la mise en valeur d'un patrimoine infrastructurel territorialisé, et d'autre part la reconstruction d'une identité territoriale. Les politiques locales prennent ainsi appui sur les valeurs qui sous-tendent ces éléments ainsi que sur des modalités rhétoriques, pour impulser en profondeur une dynamique de changement, plus malaisée à mettre en œuvre partir des outils politiques habituels

Peritoneal carcinomatosis from gastric cancer: a multi-institutional study of 159 patients treated by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy

BACKGROUND: Peritoneal carcinomatosis (PC) from gastric cancer has long been regarded a terminal disease with a short median survival. New locoregional therapeutic approaches combining cytoreductive surgery with perioperative intraperitoneal chemotherapy (PIC) have evolved and suggest improved survival. MATERIALS AND METHODS: A retrospective multicentric study was performed in French-speaking centers to evaluate the toxicity and the principal prognostic factors in order to identify the best indications. All patients had cytoreductive surgery and PIC: hyperthermic intraperitoneal chemotherapy (HIPEC) and/or early postoperative intraperitoneal chemotherapy (EPIC). RESULTS: The study included 159 patients from 15 institutions between February 1989 and August 2007. The median follow-up was 20.4 months. HIPEC was the PIC used for 150 procedures. Postoperative mortality and grade 3-4 morbidity rates were 6.5 and 27.8%, respectively. By multivariate analysis, the institution had a significant influence on toxicity. The overall median survival was 9.2 months and 1-, 3-, and 5-year survival rates were 43, 18, and 13%, respectively. The only independent prognostic indicator by multivariate analysis was the completeness of cytoreductive surgery. For patients treated by complete cytoreductive surgery, the median survival was 15 months with a 1-, 3-, and 5-year survival rate of 61, 30, and 23%, respectively. CONCLUSIONS: The therapeutic approach combining cytoreductive surgery with PIC for patients with gastric carcinomatosis may achieve long-term survival in a selected group of patients (limited and resectable PC). The high mortality rate underlines this necessarily strict selection that should be reserved to experienced institutions involved in the management of PC and gastric surgery

Digital behaviour change interventions to increase vegetable intake in adults: A systematic review

Background: Digital interventions may help address low vegetable intake in adults, however there is limited understanding of the features that make them effective. We systematically reviewed digital interventions to increase vegetable intake to 1) describe the effectiveness of the interventions; 2) examine links between effectiveness and use of co-design, personalisation, behavioural theories, and/or a policy framework; and 3) identify other features that contribute to effectiveness. Methods: A systematic search strategy was used to identify eligible studies from MEDLINE, Embase, PsycINFO, Scopus, CINAHL, Cochrane Library, INFORMIT, IEEE Xplore and Clinical Trial Registries, published between January 2000 and August 2022. Digital interventions to increase vegetable intake were included, with effective interventions identified based on statistically significant improvement in vegetable intake. To identify policy-action gaps, studies were mapped across the three domains of the NOURISHING framework (i.e., behaviour change communication, food environment, and food system). Risk of bias was assessed using Cochrane tools for randomized, cluster randomized and non-randomized trials. Results: Of the 1,347 records identified, 30 studies were included. Risk of bias was high or serious in most studies (n = 25/30; 83%). Approximately one quarter of the included interventions (n = 8) were effective at improving vegetable intake. While the features of effective and ineffective interventions were similar, embedding of behaviour change theories (89% vs 61%) and inclusion of stakeholders in the design of the intervention (50% vs 38%) were more common among effective interventions. Only one (ineffective) intervention used true co-design. Although fewer effective interventions included personalisation (67% vs 81%), the degree of personalisation varied considerably between studies. All interventions mapped across the NOURISHING framework behaviour change communication domain, with one ineffective intervention also mapping across the food environment domain. Conclusion: Few digital interventions identified in this review were effective for increasing vegetable intake. Embedding behaviour change theories and involving stakeholders in intervention design may increase the likelihood of success. The under-utilisation of comprehensive co-design methods presents an opportunity to ensure that personalisation approaches better meet the needs of target populations. Moreover, future digital interventions should address both behaviour change and food environment influences on vegetable intake

Epigenomic profiling of the infrapatellar fat pad in osteoarthritis

Osteoarthritis is a prevalent, complex disease of the joints, and affects multiple intra-articular tissues. Here, we have examined genome-wide DNA methylation profiles of primary infrapatellar fat pad and matched blood samples from 70 osteoarthritis patients undergoing total knee replacement surgery. Comparing the DNA methylation profiles between these tissues reveal widespread epigenetic differences. We produce the first genome-wide methylation quantitative trait locus (mQTL) map of fat pad, and make the resource available to the wider community. Using two-sample Mendelian randomization and colocalization analyses, we resolve osteoarthritis GWAS signals and provide insights into the molecular mechanisms underpinning disease aetiopathology. Our findings provide the first view of the epigenetic landscape of infrapatellar fat pad primary tissue in osteoarthritis