An Analysis of Sound Exposure in a University Instrumental Music Rehearsal Venue

The purpose of this study is to collect and analyze the sound load exposure of a population of university music students participating in instrumental music ensemble rehearsal

Energy planning and forecasting approaches for supporting physical improvement strategies in the building sector: a review

The strict CO2 emission targets set to tackle the global climate change associated with greenhouse gas emission exerts so much pressure on our cities which contribute up to 75% of the global carbon dioxide emission level, with buildings being the largest contributor (UNEP, 2015). Premised on this fact, urban planners are required to implement proactive energy planning strategies not only to meet these targets but also ensure that future cities development is performed in a way that promotes energy-efficiency. This article gives an overview of the state-of-art of energy planning and forecasting approaches for aiding physical improvement strategies in the building sector. Unlike previous reviews, which have only addressed the strengths as well as weaknesses of some of the approaches while referring to some relevant examples from the literature, this article focuses on critically analysing more approaches namely; 2D GIS and 3DGIS (CityGML) based energy prediction approaches, based on their frequent intervention scale, applicability in the building life cycle, and conventional prediction process. This will be followed by unravelling the gaps and issues pertaining to the reviewed approaches. Finally, based on the identified problems, future research prospects are recommended

Di-butyl Phthalate Disrupts Muscle, Motor and Sensory Neuron Development in Embryonic Zebrafish

Phthalates are added to plastics to enhance its flexibility, durability and transparency. Phthalates are found in a wide range of goods including household, agricultural and medical products as well as building and industrial materials. Phthalates are not covalently bound to plastics and leach into the environment. Phthalates are now pervasive and ubiquitously present in the atmosphere, soil and sediment, surface and wastewater. Phthalates are known endocrine disruptors and their effects on male and female reproduction are well noted. However, studies on the developmental effects of di-butyl phthalate (DBP) are limited. Here we investigate the developmental toxicity of DBP on motor and sensory neuron populations and the muscle structures motor neurons innervate using the zebrafish vertebrate model system. We investigate these effects during the time window of development spanning the period where embryonic patterning determines adult structures. We find that treatment with DBP induces loss and disorganization of primary motor neuron innervation of the somatic tissue with concomitant disruptions to muscle fiber organization. Furthermore, we find disruptions to sensory motor neuron development including defects in dorsal root ganglion and their peripherally extending axons. Rohon-Beard sensory neurons were also disrupted showing loss of the bilateral soma positioning along the length of the spinal cord and their afferent axonal projections to the epithelium. Thus, we conclude that DBP is toxic to developing motor and sensory neurons during embryonic development

Di-butyl Phthalate Disrupts Muscle, Motor and Sensory Neuron Development in Embryonic Zebrafish

Phthalates are added to plastics to enhance its flexibility, durability and transparency. Phthalates are not covalently bound to plastics and leach into the environment. Phthalates are now pervasive and ubiquitously present in the atmosphere, soil and sediment, surface and wastewater. Phthalates are known endocrine disruptors and their effects on male and female reproduction are well noted. However, studies on the developmental effects of di-butyl phthalate (DBP) are limited. Here we investigated the developmental toxicity of DBP on motor and sensory neuron populations and the muscle structures motor neurons innervate using the zebrafish vertebrate model system. We investigated these effects during the time window of development spanning the period where embryonic patterning determines adult structures. We found that treatment with 2.5 μM DBP from 6 h post-fertilization (hpf) until 72hpf induces loss and disorganization of primary motor neuron innervation of the somatic tissue with concomitant disruptions to muscle fiber organization. Furthermore, we found disruptions to sensory motor neuron development including defects in dorsal root ganglion and their peripherally extending axons. Rohon-Beard sensory neurons were also disrupted showing loss of the bilateral soma positioning along the length of the spinal cord and their afferent axonal projections to the epithelium. Thus, we concluded that DBP is toxic to developing motor and sensory neurons during embryonic development