15 research outputs found
La performance dans les réseaux de distribution : comparaison des indicateurs financiers et marketing
National audienc
La performance dans les réseaux de distribution : comparaison des indicateurs financiers et marketing
Introduction Dans un contexte concurrentiel particulièrement exacerbé, les réseaux de distribution doivent pouvoir évaluer avec rigueur et précision les performances individuelles de chacun de leurs points de vente. Si cette notion mesure la capacité de l’entreprise à générer des résultats, comme énoncé par F. Pinardon (1989), son évaluation diffère selon les points de vue que l’on retient. Aussi, nous choisissons de nous concentrer sur la performance commerciale et financière des réseaux de ..
Existe-t-il un lien entre la performance financière et la performance marketing?
International audienceCette étude s’intéresse au lien entre la performance financière et la performance marketing d’un réseau de points de vente à partir d’un échantillon de 39 supermarchés. Une comparaison entre les scores d’efficience marketing et les ratios de rentabilités économique et financière a été menée. Nos résultats montrent l’existence d’une corrélation significative entre l’efficience marketing et la performance financière. Une régression PLS mesure le sens et l’intensité de la relation entre ces deux types d’efficience. Il apparaît que l’amélioration du score marketing accroît de manière non négligeable les indicateurs de performance financière
The cryo-EM structure of a ribosome–Ski2-Ski3-Ski8 helicase complex
International audienceSki2-Ski3-Ski8 (Ski) is a helicase complex functioning with the RNA-degrading exosome to mediate the 3'-5' messenger RNA (mRNA) decay in turnover and quality-control pathways. We report that the Ski complex directly associates with 80S ribosomes presenting a short mRNA 3' overhang. We determined the structure of an endogenous ribosome-Ski complex using cryo-electron microscopy (EM) with a local resolution of the Ski complex ranging from 4 angstroms (Å) in the core to about 10 Å for intrinsically flexible regions. Ribosome binding displaces the autoinhibitory domain of the Ski2 helicase, positioning it in an open conformation near the ribosomal mRNA entry tunnel. We observe that the mRNA 3' overhang is threaded directly from the small ribosomal subunit to the helicase channel of Ski2, primed for ongoing exosome-mediated 3'-5' degradation
Foreign Cloth, Local Habits: Clothing, Regalia, and the Art of Conversion in the Early Modern Kingdom of Kongo
Da decisão do rei de abraçar o catolicismo na virada do século XVI até o avanço do colonialismo imperialista do final do século XIX, os homens e mulheres do reino do Congo na África central criativamente misturaram, fundiram e redefiniram formas visuais locais e estrangeiras, pensamento religioso e conceitos políticos numa visão de mundo original, coerente e em constante evolução do cristianismo congo. Práticas de vestimenta e, em especial, insígnias reais demonstram a astuciosa conversão do reino sob o ímpeto de seus monarcas e aristocratas. Através de suas vestimentas e insígnias a elite do reino combinou e remodelou o estrangeiro e o local, o velho e o novo, materiais e emblemas nos arautos de poder, riqueza e, inevitavelmente, história cristã no Congo. Proponho utilizar o conceito de espaço de correlação como elemento-chave para analisar essas elaboradas transformações religiosas, políticas e materiais, em evolução constante, de forma a estabelecer um foco minucioso em objetos culturais tais como indumentária, chapéus, espadas e imagens religiosas.From their king’s decision to embrace Catholicism at the turn of the sixteenth century to the advent of imperial colonialism in the late eighteen hundreds, the men and women of the central African kingdom of Kongo creatively mixed, merged, and redefined local and foreign visual forms, religious thought, and political concepts into the novel, coherent, but also constantly evolving worldview of Kongo Christianity. Sartorial practices and regalia in particular showcased the artful conversion of the realm under the impetus of its monarchs and aristocrats. In their clothing and insignia, the kingdom’s elite combined and recast foreign and local, old and new, material and emblems into heralds of Kongo Christian power, wealth, and, eventually history. I propose to use the concept of the space of correlation as a key to analyze these elaborate, and constantly evolving religious, political, and material transformations through an attentive focus on cultural objects such as clothing, hats, swords, and saint figures
Risk factors of perioperative morbimortality after laparoscopic sleeve gastrectomy: a club coelio multicenter study.
OBJECTIVES: Postoperative complications after Laparoscopic sleeve gastrectomy (LSG) can dramatically compromise patient's outcome. The aim of this study is to analyze the per- and postoperative short-term outcomes after LSG and to assess predictive risk factors of complications.
METHODS: The study group consisted of 790 patients (610 women and 180 men) who underwent LSG In 2014. All interventions were performed by 18 experienced surgeons members of the Club Coelio. Data about preoperative work-up, surgical techniques, 30-days postoperative morbidity and mortality were collected. Endpoints were perioperative morbidity and mortality and assessment of potential risk factors for complications.
RESULTS: Mean age and body mass index were respectively 39 years and 41.5kg/m2. Ninety-one patients (11.5%) had previous bariatric surgery. Morbidity rate was 4.7% (37/790) including 16 leaks (2.0%) and 9 bleedings (1.1%) and no deaths. Risk factors for leak were: previous adjustable banding (p = .0051), with no difference between removal of the banding and LSG in 1 or 2 steps, and type of endostapler (p = .0129).
CONCLUSIONS: Leakage after Sleeve was rare but still observed even in experienced hands. The leak rate is particularly high when LSG is performed after adjustable gastric banding removal