3,945 research outputs found
Ecotourism between theory and practice: empirical analysis of the tourism industry of whale watching in H\ufasav\uedk (Iceland)
Whale watching is a dynamic industry and, in particular in a country like Iceland, where tourism is currently playing a leading role in the national economy and where nature \u2013 understood in a broad sense \u2013 represents the main attraction for visitors, whale watching, rapidly grown during the last years, shows an evident potential under an ecotouristic point of view. In recent times, an increasing need for the understanding of interactions between humans (tourists) and wildlife (whales) emerged, highlighting the interest towards environmental conservation, protection and preservation matters and towards the search for activities, and modalities, that could essentially contribute to the sustainability of tourism experiences, such as wildlife tourism ones. It is difficult to argue with the fact that whale watching uses the whale \u201casset\u201d in a non-destructive way, unlike whaling, activity still commercially conducted in Iceland, but at the same time it can\u2019t be considered ecotouristic and sustainable a priori. In fact, several studies point out how tourism has a disturbing effect on wildlife and negatively affects their ecology and short- to long-term behaviours. This article, after a general introduction on the main ecotourism principles, examines the whale watching industry of the \u201cWhale Capital of Iceland\u201d, H\ufasav\uedk, and it mainly focuses on the results and data of two researches conducted in the field \u2013 respectively among whale watchers and among the local whale watching companies. The purpose of this work is to investigate if and how H\ufasav\uedk whale watching is following an environmentally sustainable and ecotouristic path, and to bring into light its strengths and weaknesses as a whale watching destination
Exploring forest infrastructures equipment through multivariate analysis: complementarities, gaps and overlaps in the Mediterranean basin
The countries of the Mediterranean basin face several challenges regarding the sustainability of forest ecosystems and the delivery of crucial goods and services that they provide in a context of rapid global changes. Advancing scientific knowledge and foresting innovation is essential to ensure the sustainable management of Mediterranean forests and maximize the potential role of their unique goods and services in building a knowledge-based bioeconomy in the region. In this context, the European project FORESTERRA ("Enhancing FOrest RESearch in the MediTERRAnean through improved coordination and integration”) aims at reinforcing the scientific cooperation on Mediterranean forests through an ambitious transnational framework in order to reduce the existing research fragmentation and maximize the effectiveness of forest research activities. Within the FORESTERRA project framework, this work analyzed the infrastructures equipment of the Mediterranean countries belonging to the project Consortium. According to the European Commission, research infrastructures are facilities, resources and services that are used by the scientific communities to conduct research and foster innovation. To the best of our knowledge, the equipment and availability of infrastructures, in terms of experimental sites, research facilities and databases, have only rarely been explored. The aim of this paper was hence to identify complementarities, gaps and overlaps among the different forest research institutes in order to create a scientific network, optimize the resources and trigger collaborations
MeltingPlot, a user-friendly online tool for epidemiological investigation using High Resolution Melting data
BACKGROUND: The rapid identification of pathogen clones is pivotal for effective epidemiological control strategies in hospital settings. High Resolution Melting (HRM) is a molecular biology technique suitable for fast and inexpensive pathogen typing protocols. Unfortunately, the mathematical/informatics skills required to analyse HRM data for pathogen typing likely limit the application of this promising technique in hospital settings.RESULTS: MeltingPlot is the first tool specifically designed for epidemiological investigations using HRM data, easing the application of HRM typing to large real-time surveillance and rapid outbreak reconstructions. MeltingPlot implements a graph-based algorithm designed to discriminate pathogen clones on the basis of HRM data, producing portable typing results. The tool also merges typing information with isolates and patients metadata to create graphical and tabular outputs useful in epidemiological investigations and it runs in a few seconds even with hundreds of isolates.AVAILABILITY: https://skynet.unimi.it/index.php/tools/meltingplot/ .CONCLUSIONS: The analysis and result interpretation of HRM typing protocols can be not trivial and this likely limited its application in hospital settings. MeltingPlot is a web tool designed to help the user to reconstruct epidemiological events by combining HRM-based clustering methods and the isolate/patient metadata. The tool can be used for the implementation of HRM based real time large scale surveillance programs in hospital settings
Genomics of dwarfism in Italian local chicken breeds
The identification of the dwarf phenotype in chicken is based on body weight, height, and shank length, leaving the differentiation between dwarf and small breeds ambiguous. The aims of the present study were to characterize the sequence variations associated with the dwarf phenotype in three Italian chicken breeds and to investigate the genes associated with their phenotype. Five hundred and forty-one chickens from 23 local breeds (from 20 to 24 animals per breed) were sampled. All animals were genotyped with the 600 K chicken SNP array. Three breeds were described as “dwarf”, namely, Mericanel della Brianza (MERI), Mugellese (MUG), and Pepoi (PPP). We compared MERI, MUG, and PPP with the four heaviest breeds in the dataset by performing genome-wide association studies. Results showed significant SNPs associated with dwarfism in the MERI and MUG breeds, which shared a candidate genomic region on chromosome 1. Due to this similarity, MERI and MUG were analyzed together as a meta-population, observing significant SNPs in the LEMD3 and HMGA2 genes, which were previously reported as being responsible for dwarfism in different species. In conclusion, MERI and MUG breeds seem to share a genetic basis of dwarfism, which differentiates them from the small PPP breed.Depto. de Producción AnimalFac. de VeterinariaTRUEMinistry of Agricultural, Food and Forestry Policies (Italy)China Scholarship Councilpu
Cardiac resynchronization therapy-defibrillator improves long-term survival compared with cardiac resynchronization therapy-pacemaker in patients with a class IA indication for cardiac resynchronization therapy: Data from the Contak Italian Registry
Aims In candidates for cardiac resynchronization therapy (CRT), the choice between pacemaker (CRT-P) and defibrillator (CRT-D) implantation is still debated. We compared the long-term prognosis of patients who received CRT-D or CRT-P according to class IA recommendations of the European Society of Cardiology (ESC) and who were enrolled in a multicentre prospective registry. Methods and results A total of 620 heart failure patients underwent successful implantation of a CRT device and were enrolled in the Contak Italian Registry. This analysis included 266 patients who received a CRT-D and 108 who received a CRT-P according to class IA ESC indications. Their survival status was verified after a median follow-up of 55 months. During follow-up, 73 CRT-D and 44 CRT-P patients died (rate 6.6 vs. 10.4%/year; log-rank test, P = 0.020). Patients receiving CRT-P were predominantly older, female, had no history of life-threatening ventricular arrhythmias, and more frequently presented non-ischaemic aetiology of heart failure, longer QRS durations, and worse renal function. However, the only independent predictor of death from any cause was the use of CRT-P (hazard ratio, 1.97; 95% confidence interval, 1.21–3.16; P = 0.007). Conclusion The implantation of CRT-D, rather than CRT-P, may be preferable in patients presenting with current class IA ESC indications for CRT. Indeed, CRT-D resulted in greater long-term survival and was independently associated with a better prognosis
RNAseq reveals modulation of genes involved in fatty acid biosynthesis in chicken liver according to genetic background, sex, and diet
RNAseq reveals modulation of genes involved in fatty acid biosynthesis in chicken liver according to genetic background, sex and diet
Pseudo solid-appearing pancreatic serous microcystic adenomas: Histologic diagnosis with the EUS core biopsy fork-tip needle
Background and Objectives: Despite rarely, serous cystic adenoma (SCA) can assume a pseudo-solid aspect mimicking other pancreatic neoplasm as neuroendocrine tumor. EUS-FNA cytology has low diagnostic accuracy due to the scant cellularity of the collected samples. Histological diagnosis is usually made after resection. Recently, end-cutting needles for EUS-fine-needle biopsy (EUS-FNB), which obtain tissue cores by penetrating the lesions, have been developed. We aimed to assess the capability of EUS-FNB with SharkCore (TM) needles in the preoperative diagnosis of serous cystic adenoma pseudo-solid-appearing on imaging (Sa-SCA). Materials and Methods: Between January 2016 and January 2018, data from consecutive adult patients, who were referred for EUS-FNB of a solid pancreatic lesion and were diagnosed with having SCA, were retrieved from a single-center institutional database. Results: Two patients were excluded because of microcystic aspect at EUS. Histological diagnosis of SCA was made by EUS-FNB in the remaining 7 patients (5 females; mean age of 62.5 years). Lesions (mean size of 19.8 mm) were hypervascular on cross-sectional imaging, slightly hyperdense magnetic resonance imaging with T2-weighted images can, and negative at Ga-68-somatostatin receptor positron emission tomography and (18)fluoro-deoxyglucose positron emission tomography. EUS-FNB samples were judged adequate for a definitive diagnosis in all cases, achieving specimens suitable for histological evaluation and several ancillary stains. Histochemical positivity for periodic acid-Schiff (PAS) and PAS with diastase digestion was observed in 7/7 cases. Immunohistochemical positivity for alpha-inhibin (7/7), GLUT1 (6/6), MUC6 (5/5), and negativity for synaptophysin (7/7) and chromogranin A (2/2) favored SCA diagnosis. Conclusions: In the case of preoperative workup suspected for Sa-SCA, a "forward acquiring" needle could improve the rate of preoperative histological diagnosis
Euclidean three-point function in loop and perturbative gravity
We compute the leading order of the three-point function in loop quantum
gravity, using the vertex expansion of the Euclidean version of the new spin
foam dynamics, in the region of gamma<1. We find results consistent with Regge
calculus in the limit gamma->0 and j->infinity. We also compute the tree-level
three-point function of perturbative quantum general relativity in position
space, and discuss the possibility of directly comparing the two results.Comment: 16 page
Sardinia aperture array demonstrator: measurement campaigns of radio frequency interferences
Measurement campaigns of radio frequency interferences (RFIs) represent a fundamental aspect to optimize data collected by radio astronomical observations. In order to monitor the state of unwanted man-made signals, every radio telescope needs to have a radio frequency map in the frequencies range of its receivers. The Sardinia Aperture Array Demonstrator (SAD) is an Italian aperture array demonstrator composed of prototypical Vivaldi antennas designed to work at frequencies below 500 MHz. The antennas are located at the Sardinia Radio Telescope (SRT) site and they are arranged with a versatile approach that is able to provide different array configurations. In this paper, we present the results of measurement campaigns conducted with the SAD antennas at the SRT observing site with the aim to monitor the evolution of RFI scenario from 2016 to date. The signal acquisition chain and the software tool used for RFI detection are, also, presented
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