The Career Readiness of Intercollegiate Athletes: Is There a Gender Gap?

Career development is one of the major objectives of universities. It is well-known that intercollegiate athletes have many time commitments that make it more challenging for them to focus on their career development. To compound this issue, the effectiveness of career development efforts may be impacted by the gender of the intercollegiate athlete. The purpose of this study was to examine the career readiness of student-athletes, focusing on differences based on gender. This was accomplished through the lenses of the social cognitive career theory and career decision self-efficacy. A total of 137 intercollegiate student-athletes at a large Midwestern university completed a career readiness instrument. It was found that there were differences between genders in the intercollegiate athlete’s perceived career readiness. Female intercollegiate student-athletes indicated lower levels of ability on career related skills, less confidence in their problem solving, higher levels of general indecisiveness about career choice, and a higher need for self-knowledge. There were similarities between the genders as well, such as the need for more career information and levels of career choice anxiety. Recommendations for programs to assist student-athletes in their career readiness and for areas of future research are provided

Data Descriptor: DataTri, a database of American triatomine species occurrence

Trypanosoma cruzi, the causative agent of Chagas disease, is transmitted to mammals - including humans - by insect vectors of the subfamily Triatominae. We present the results of a compilation of triatomine occurrence and complementary ecological data that represents the most complete, integrated and updated database (DataTri) available on triatomine species at a continental scale. This database was assembled by collecting the records of triatomine species published from 1904 to 2017, spanning all American countries with triatomine presence. A total of 21815 georeferenced records were obtained from published literature, personal fieldwork and data provided by colleagues. The data compiled includes 24 American countries, 14 genera and 135 species. From a taxonomic perspective, 67.33% of the records correspond to the genus Triatoma, 20.81% to Panstrongylus, 9.01% to Rhodnius and the remaining 2.85% are distributed among the other 11 triatomine genera. We encourage using DataTri information in various areas, especially to improve knowledge of the geographical distribution of triatomine species and its variations in time.Fil: Ceccarelli, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; ArgentinaFil: Balsalobre, Agustin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; ArgentinaFil: Medone, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; ArgentinaFil: Cano, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; ArgentinaFil: Gonçalves, Rodrigo Gurgel. Universidade do Brasília; BrasilFil: Feliciangeli, Dora. No especifica;Fil: Vezzani, Dario. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires; ArgentinaFil: Wisnivesky Colli, Cristina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; ArgentinaFil: Gorla, David Eladio. Comision Nacional de Actividades Espaciales. Instituto de Altos Estudios Espaciales "Mario Gulich"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Marti, Gerardo Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; ArgentinaFil: Rabinovich, Jorge Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; Argentin

Comparative Microsatellite Typing of New World Leishmania infantum Reveals Low Heterogeneity among Populations and Its Recent Old World Origin

Leishmania infantum (syn. L. chagasi) is the causative agent of visceral leishmaniasis (VL) in the New World (NW) with endemic regions extending from southern USA to northern Argentina. The two hypotheses about the origin of VL in the NW suggest (1) recent importation of L. infantum from the Old World (OW), or (2) an indigenous origin and a distinct taxonomic rank for the NW parasite. Multilocus microsatellite typing was applied in a survey of 98 L. infantum isolates from different NW foci. The microsatellite profiles obtained were compared to those of 308 L. infantum and 20 L. donovani strains from OW countries previously assigned to well-defined populations. Two main populations were identified for both NW and OW L. infantum. Most of the NW strains belonged to population 1, which corresponded to the OW MON-1 population. However, the NW population was much more homogeneous. A second, more heterogeneous, population comprised most Caribbean strains and corresponded to the OW non-MON-1 population. All Brazilian L. infantum strains belonged to population 1, although they represented 61% of the sample and originated from 9 states. Population analysis including the OW L. infantum populations indicated that the NW strains were more similar to MON-1 and non-MON-1 sub-populations of L. infantum from southwest Europe, than to any other OW sub-population. Moreover, similarity between NW and Southwest European L. infantum was higher than between OW L. infantum from distinct parts of the Mediterranean region, Middle East and Central Asia. No correlation was found between NW L. infantum genotypes and clinical picture or host background. This study represents the first continent-wide analysis of NW L. infantum population structure. It confirmed that the agent of VL in the NW is L. infantum and that the parasite has been recently imported multiple times to the NW from southwest Europe

Vital Statistics of Triatominae (Hemiptera: Reduviidae) under Laboratory Conditions: IV. Panstrongylus geniculatus

A cohort of 100 eggs of Panstrongylus geniculatus (Latreille) was reared in the laboratory under constant conditions (temperature 26±1°C, 60±10% RH), with mortality and fecundity data recorded weekly. We calculated stage-specific development times, age-specific mortality and fecundity (18.4 eggs/♀/wk), and stage-specific and total preadult mortality (31.6%), and the weekly intrinsic rate of natural increase (ro = 0.096), the finite population growth rate (< = 1.109), the net reproductive rate (R0 = 60.45), and the generation time (T = 46.34 wk). Elasticity analysis showed that the dominant lifehistory trait determining < was survival (particularly the adult female's survival). Adult females dominated the stage-specific reproductive value, and the egg stage dominated the stable stage distribution (SSD). The damping ratio (rgr = 1.096) suggests a relatively rapid period of recovery to a disturbed SSD. Results were compared with one previous study and conform relatively well, considering that environmental conditions were not the same. We estimated the colonizing ability of P. geniculatus, using as a criterion the ro/b index, and obtained the value of 0.74, an indicator of a good colonizer, and similar to well-known invasive species such as Rhodnius prolixus and Triatoma infestans. The life history traits and demographic parameters here presented for P. geniculatus are discussed in terms of their usefulness for evolutionary studies and vector control activities.Fil: Rabinovich, Jorge Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; ArgentinaFil: Feliciangeli, M. Dora. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; Argentina. Universidad de Carabobo. Facultad de Ciencias de la Salud. Instituto de Investigaciones Biomédicas; Venezuel

The role of hyperthermic intraperitoneal chemotherapy using paclitaxel in platinum-sensitive recurrent epithelial ovarian cancer patients with microscopic residual disease after cytoreduction

© 2015. The authors. This document is the accepted version of a published work that appeared in final form in Annals of Surgical Oncology. To access the final edited and published work see https://doi.org/10.1245/s10434-014-4049-zEn este trabajo, se compararon 2 grupos homogéneos de pacientes con carcinomatosis peritoneal de origen ovárico recurrente, sensibles al platino en las que se realizó una citorreducción completa de la enfermedad: un grupo estaba formado por pacientes intervenidas antes y el otro después de inicio del programa de cirugía oncológica peritoneal. Bajo esta premisa se estudió como HIPEC había mejorado los resultados en pacientes con recurrencias platino-sensibles. Se trata de un aporte multidisciplinar en el que trabajamos conjuntamente los servicios de Cirugía, Ginecología y Oncología Médica. En los resultados, se encontró una mejoría a favor del tratamiento HIPEC en grupos comparables, sin diferencias significativas en ninguna de las variables preoperatorias estudiadas: Tras un análisis multivariante de los factores identificados en el análisis univariante, solo la presencia de tumores con histología indiferenciada (hazard ratio 2,57; IC 95 % 1,21–5,46; p < 0,05) fue un factor independiente asociado a una supervivencia libre de enfermedad reducida. La supervivencia libre de enfermedad a 1 y 3 años fue del 77 y 23 % en los pacientes del grupo I y del 77 y 45% diferencias clínicamente relevantes entre los 2 grupos, con una mejora evidente de la supervivencia a favor del grupo tratado con HIPEC. No se encontraron diferencias en cuanto a las complicaciones postoperatorias entre ambos grupos por lo que en este estudio se reforzó la idea de que HIPEC no incrementaba la morbilidad postoperatoria con su administración.Background. We analyzed the role of hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) on the microscopic component of the disease in patients with a first recurrence of platinum-sensitive ovarian cancer after complete cytoreduction (CCR). Patients and Methods. We analyzed the data of 54 patients who were operated on between January 2001 and July 2012 with the diagnosis of platinum-sensitive recurrent ovarian cancer. In all patients, it was possible to achieve a CCR. Patients were divided into two groups: group I (cytoreduction alone) consisted of 22 surgical patients and group II (cytoreduction and HIPEC) consisted of 32 patients. Results. There were no significant differences in any of the preoperative variables studied. After a multivariate analysis of factors identified in the univariate analysis, only the presence of tumors with undifferentiated histology (hazard ratio 2.57; 95 % CI 1.21–5.46; p\0.05) was an independent factor associated with a reduced disease-free survival. The 1- and 3-year disease-free survival was 77 and 23 % in patients from group I and 77 and 45 % in patients from group II, respectively, with a tendency, but no significant differences (p = 0.078). There was no significant difference in postoperative morbidity between the two groups. Conclusions. The administration of HIPEC in patients in whom it is possible to achieve a CCR of the disease has not increased postoperative morbidity and mortality rates in our center. HIPEC with paclitaxel is effective in the treatment of microscopic disease in platinum-sensitive recurrent epithelial ovarian cancer patients with microscopic residual disease after cytoreduction, although with no statistically significant difference

External Validity of Somatostatin Analogs Trials in Advanced Neuroendocrine Neoplasms: The GETNE-TRASGU Study

[Introduction] Somatostatin analogs (SSA) prolong progression-free survival (PFS) in patients with well-differentiated gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). However, the eligibility criteria in randomized clinical trials (RCTs) have been restricted, which contrasts with the vast heterogeneity found in NENs.[Methods] We identified patients with well-differentiated (Ki-67% ≤20%), metastatic GEP-NENs treated in first line with SSA monotherapy from the Spanish R-GETNE registry. The therapeutic effect was evaluated using a Bayesian Cox model. The objective was to compare survival-based outcomes from real-world clinical practice versus RCTs.[Results] The dataset contained 535 patients with a median age of 62 years (range: 26–89). The median Ki-67% was 4 (range: 0–20). The most common primary tumor sites were as follows: midgut, 46%; pancreas, 34%; unknown primary, 10%; and colorectal, 10%. Half of the patients received octreotide LAR (n = 266) and half, lanreotide autogel (n = 269). The median PFS was 28.0 months (95% CI: 22.1–32.0) for octreotide versus 30.1 months (95% CI: 23.1–38.0) for lanreotide. The overall hazard ratio for lanreotide versus octreotide was 0.90 (95% credible interval: 0.71–1.12). The probability of effect sizes >30% with lanreotide versus octreotide was 2 and 6% for midgut and foregut NENs, respectively.[Conclusion] Our study evaluated the external validity of RCTs examining SSAs in the real world, as well as the main effect-modifying factors (progression status, symptoms, tumor site, specific metastases, and analytical data). Our results indicate that both octreotide LAR and lanreotide autogel had a similar effect on PFS. Consequently, both represent valid alternatives in patients with well-differentiated, metastatic GEP-NENs.The study has been funded by a restricted grant from Novartis Farmacéutica, S.A. RGETNE and the GETNE group is partially funded by Ipsen, Novartis, Pfizer and AAA. Dr Angela Lamarca received funding from ASCO Conquer Cancer Foundation Young Investigator Award and The Christie Charity. Dr Jorge Barriuso received funding from the received funding from the ENETS Centre of Excellence Fellowship Grant Award.Peer reviewe