641 research outputs found

    Forward EW Physics at the LHC

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    Measurements of electroweak production in the forward region at the LHC provide unique and complementary information to those performed in the central region. Studies have been performed not just by LHCb, a dedicated forward detector, but also by ATLAS and CMS, which are primarily situated in the central region but can exploit forward calorimetry coverage to contribute to the understanding of SM processes in the forward region.Comment: To appear in LHCP 2015 Proceeding

    Observation of Top Quark Production in the Forward Region at LHCb

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    Forward top production is observed, in the ÎŒ+b{\mu}+b final state, with the 3 fb−1^{-1} Run I dataset collected by the LHCb detector. The combined cross-section for ttˉt\bar{t} and single top production at s=7\sqrt{s}=7 TeV and s=8\sqrt{s}=8 TeV is measured, for muons from the W boson with pT>25p_{\rm T} > 25 GeV in the pseudo-rapidity range 2.0<η<< \eta <4.5 and with a b-tagged jet with 50<pT<100 < p_{\rm T} < 100 GeV in the pseudorapidity range 2.2<η<< \eta <4.2. The production cross-sections are found to be in agreement with NLO predictions.Comment: To appear in Proceedings of LHCP 201

    Understanding and constraining the PDF uncertainties in a W boson mass measurement with forward muons at the LHC

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    Precision electroweak tests are a powerful probe of physics beyond the Standard Model, but the sensitivity is limited by the precision with which the WW boson mass (MWM_W) has been measured. The Parton Distribution Function (PDF) uncertainties are a potential limitation for measurements of MWM_W with LHC data. It has recently been pointed out that, thanks to LHCb's unique forward rapidity acceptance, a new measurement of MWM_W by LHCb can improve this situation. Here we report on a detailed study on the mechanism driving the PDF uncertainty in the LHCb measurement of MWM_W, and propose an approach which should reduce this uncertainty by roughly a factor of two using LHCb Run 2 data.Comment: 18 pages, 17 figures, submitted to EPJ

    The PDF4LHC report on PDFs and LHC data: Results from Run I and preparation for Run II

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    The accurate determination of the Parton Distribution Functions (PDFs) of the proton is an essential ingredient of the Large Hadron Collider (LHC) program. PDF uncertainties impact a wide range of processes, from Higgs boson characterisation and precision Standard Model measurements to New Physics searches. A major recent development in modern PDF analyses has been to exploit the wealth of new information contained in precision measurements from the LHC Run I, as well as progress in tools and methods to include these data in PDF fits. In this report we summarise the information that PDF-sensitive measurements at the LHC have provided so far, and review the prospects for further constraining PDFs with data from the recently started Run II. This document aims to provide useful input to the LHC collaborations to prioritise their PDF-sensitive measurements at Run II, as well as a comprehensive reference for the PDF-fitting collaborations.Comment: 55 pages, 13 figure

    Stratification of asthma phenotypes by airway proteomic signatures

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    © 2019 Background: Stratification by eosinophil and neutrophil counts increases our understanding of asthma and helps target therapy, but there is room for improvement in our accuracy in prediction of treatment responses and a need for better understanding of the underlying mechanisms. Objective: We sought to identify molecular subphenotypes of asthma defined by proteomic signatures for improved stratification. Methods: Unbiased label-free quantitative mass spectrometry and topological data analysis were used to analyze the proteomes of sputum supernatants from 246 participants (206 asthmatic patients) as a novel means of asthma stratification. Microarray analysis of sputum cells provided transcriptomics data additionally to inform on underlying mechanisms. Results: Analysis of the sputum proteome resulted in 10 clusters (ie, proteotypes) based on similarity in proteomic features, representing discrete molecular subphenotypes of asthma. Overlaying granulocyte counts onto the 10 clusters as metadata further defined 3 of these as highly eosinophilic, 3 as highly neutrophilic, and 2 as highly atopic with relatively low granulocytic inflammation. For each of these 3 phenotypes, logistic regression analysis identified candidate protein biomarkers, and matched transcriptomic data pointed to differentially activated underlying mechanisms. Conclusion: This study provides further stratification of asthma currently classified based on quantification of granulocytic inflammation and provided additional insight into their underlying mechanisms, which could become targets for novel therapies

    Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

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    The production of tt‟ , W+bb‟ and W+cc‟ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓΜ , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of tt‟t\overline{t}, W+bb‟W+b\overline{b} and W+cc‟W+c\overline{c} is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 ±\pm 0.02 \mbox{fb}^{-1}. The WW bosons are reconstructed in the decays W→ℓΜW\rightarrow\ell\nu, where ℓ\ell denotes muon or electron, while the bb and cc quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

    Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

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    Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

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    Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a ZZ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 <pT<100< p_{\textrm{T}} < 100 GeV and in the pseudorapidity range 2.5<η<42.5 < \eta < 4. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb−1^{-1}. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages
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