Drug Plant Seed Viability Preservation by Cryoconservation

The article considers the possibility of cryopreservation of seeds of several species of drug plants in Central Kazakhstan – Tanacetum ulutavicum, Niedzwedzkia semiretschenskia, Rhaponticum carthamoides. To increase the amount of viable seeds after liquid nitrogen freezing, we used different defrosting temperatures, deposited seeds with different moisture contents and used different containers for cryopreservation. Recommendations, concerning conditions of cryopreservation of seeds of these drug plant species were developed, basing on the obtained results

Saponaria officinalis Seeds Germination Morphology and Biology

This work deals with the study of influence of terms and storage conditions on Saponaria officinalis seed quality, stored in different containers (paper, plastic, fabric and glass), in the different temperature conditions, under light or darkness. The morphology, biology of Saponaria officinalis seeds was described. Basing in the obtained results, we recommend to store Saponaria officinalis seeds within 3 months in paper container at the temperature of - 18˚С

ANALYSIS OF HYDROGEN-INDUCED DIRECT PHASE TRANSFORMATION KINETICS IN Y2FE17 ALLOY ON THE BASE OF KOLMOGOROV'S MODEL

Кинетика индуцированного водородом прямого фазового превращения в магнитотвердом сплаве Y2Fe17 проанализирована в рамках кинетической модели Колмогорова. Установлено, что индуцированное водородом прямое фазовое превращение в магнитотвердом сплаве Y2Fe17 классифицируется как диффузионно-контролируемое превращение, реализующееся по механизму зарождения и роста с убывающей скоростью зарождения центров новых фаз − -Fe и YH2. На основе кинетической теории фазовых превращений Колмогорова получено кинетическое уравнение, хорошо описывающее изотермические кинетические кривые фазового превращения в сплаве Y2Fe17 в зависимости от температуры превращения.inetics of the hydrogen induced direct phase transformation in Y2Fe17 hard magnetic alloy has been analyzed in framework of Kolmogorov's kinetic model. It is established that hydrogen induced direct phase transformation in Y2Fe17 hard magnetic alloy classified as diffusion controlled transformation which occurs by mechanism of nucleation and growth with decreasing nucleation rate of new phases − α-Fe and YH2. On the base of Kolmogorov's kinetic theory of the phase transformations has been obtained kinetic equation that well described the isothermal kinetic curves of phase transformation in Y2Fe17 alloy depending on transformation temperature

Study of Water-holding Indicators of Various Environmental Groups of Trees and Shrubs under Zhezkazgan Region Conditions

The article studies water content of leaves and water-holding capacity of trees and shrubs of twelve kinds of plants. Water-holding capacity analysis was conducted in summer, which is stressful for the plants. It was determined that water-holding capacity of plants is minimal in spring and summer, while these functions increase in mid and late summer. Basing on these data, all trees and shrubs were divided into 3 groups by water-holding capacity: low, medium and high. Plants of the third group are recommended for the semi-arid zone Zhezkazgan Region landscaping

Incidence of pancreatic malignancies in the Russian Federation: a retrospective cohort trial

Background. Pancreatic malignancies pose a challenging medical and social problem. The assessment of oncology care requires an in-depth analysis of morbidity and lethality. At a relatively improved prevalence and lethality in other-locale malignancies, pancreatic cancer remains a disappointing situation. Medical statistics in pancreatic malignancy can be used for the specialty care prediction and implementation of measures to advance diagnostic algorithms and population screening.Objectives. An assessment of the pancreatic malignancy incidence and mortality in the adult population of Russian Federation over a six-year period.Methods. A retrospective descriptive cohort trial included statistical data on morbidity and mortality in pancreatic cancer patients (C 25.0-C 25.9) according to the ICD of 10th edition. A comparison cohort sampled patients with all-locale neoplasms (C00-C96) according to the ICD of 10th edition, excluding nosologies C25.0-C25.9. Information was sourced in the Federal Statistical Abstracts for the period of 2014-2019. Inclusion criteria: the study cohort included pancreatic cancer patients diagnosed at the age of 18 years on, and comparison cohort — malignancy patients diagnosed with at 18 years on. The main study indicator were the pancreatic cancer morbidity and mortality figures in Russia.Results. Pancreatic cancer was shown to co-increase main morbidity figures in 2014-2019 compared to malignant neoplasms of other localities. Other-locale malignancies decreased mortality over the study period, which was not the case with pancreatic cancer. The period exhibits more frequent morphologically verified diagnoses and higher population numbers registered with specialty dispensaries. Registered pancreatic cancer figures are significantly higher in the female population. The proportion of advanced pancreatic malignancies at primary diagnosis exceeds that of early stages.Conclusion. The findings expose a demand for improving the system of early pancreatic cancer detection via intensifying preventive measures to capture the patient’s predisposition and screening techniques for early disease diagnosis. An active outpatient surveillance is prerequisite to an effective population involvement in dispensary screening

АНАЛИЗ МНЕНИЯ БОЛЬНЫХ О КАЧЕСТВЕ СТАЦИОНАРНОЙ ПОМОЩИ В ОТДЕЛЕНИЯХ КАРДИОЛОГИЧЕСКОГО ПРОФИЛЯ С РАЗНОЙ ИНТЕНСИВНОСТЬЮ УХОДА И ЛЕЧЕНИЯ

The article presents the analysis of the results of sociological studies of the patients admitted to cardiac unit for patients with myocardial infarction and to the Department of medical rehabilitation for such patients. We studied the influence of ethical aspects of conduct of the medical staff, and household conditions in the offices on the level of patients' satisfaction with quality of medical care.Представлен анализ результатов социологического исследования пациентов, госпитализированных в кардиологическое отделение для больных инфарктом миокарда и в отделение медицинской реабилитации для таких больных. Изучено влияние деонтологических аспектов поведения медицинского персонала и бытовых условий пребывания в отделениях на уровень удовлетворенности пациентов качеством медицинской помощи

Pore timing:the evolutionary origins of the nucleus and nuclear pore complex

The name “eukaryote” is derived from Greek, meaning “true kernel”, and describes the domain of organisms whose cells have a nucleus. The nucleus is thus the defining feature of eukaryotes and distinguishes them from prokaryotes (Archaea and Bacteria), whose cells lack nuclei. Despite this, we discuss the intriguing possibility that organisms on the path from the first eukaryotic common ancestor to the last common ancestor of all eukaryotes did not possess a nucleus at all—at least not in a form we would recognize today—and that the nucleus in fact arrived relatively late in the evolution of eukaryotes. The clues to this alternative evolutionary path lie, most of all, in recent discoveries concerning the structure of the nuclear pore complex. We discuss the evidence for such a possibility and how this impacts our views of eukaryote origins and how eukaryotes have diversified subsequent to their last common ancestor

Combined searches for the production of supersymmetric top quark partners in proton–proton collisions at √s=13Te

A combination of searches for top squark pair production using proton–proton collision data at a center-of-mass energy of 13TeV at the CERN LHC, corresponding to an integrated luminosity of 137fb$^{-1}$ collected by the CMS experiment, is presented. Signatures with at least 2 jets and large missing transverse momentum are categorized into events with 0, 1, or 2 leptons. New results for regions of parameter space where the kinematical properties of top squark pair production and top quark pair production are very similar are presented. Depending on the model, the combined result excludes a top squark mass up to 1325GeV for a massless neutralino, and a neutralino mass up to 700GeV for a top squark mass of 1150GeV. Top squarks with masses from 145 to 295GeV, for neutralino masses from 0 to 100GeV, with a mass difference between the top squark and the neutralino in a window of 30GeV around the mass of the top quark, are excluded for the first time with CMS data. The results of theses searches are also interpreted in an alternative signal model of dark matter production via a spin-0 mediator in association with a top quark pair. Upper limits are set on the cross section for mediator particle masses of up to 420GeV

Observation of the Bc+_\mathrm{c}^+ Meson in Pb-Pb and pp Collisions at sNN\sqrt{s_{\mathrm{NN}}} = 5.02 TeV and Measurement of its Nuclear Modification Factor

The B$_\mathrm{c}^+$ meson is observed for the first time in heavy ion collisions. Data from the CMS detector are used to study the production of the B$_\mathrm{c}^+$ meson in lead-lead (Pb-Pb) and proton-proton (pp) collisions at a center-of-mass energy per nucleon pair of $\sqrt{s_{\mathrm{NN}}}$ = 5.02 TeV , via the B$_\mathrm{c}^+$ → (J/ψ → μ$^+$μ$^−$)μ$^+$ν$_μ$ decay. The B$_\mathrm{c}^+$ nuclear modification factor, derived from the PbPb-to-pp ratio of production cross sections, is measured in two bins of the trimuon transverse momentum and of the PbPb collision centrality. The B$_\mathrm{c}^+$meson is shown to be less suppressed than quarkonia and most of the open heavy-flavor mesons, suggesting that effects of the hot and dense nuclear matter created in heavy ion collisions contribute to its production. This measurement sets forth a promising new probe of the interplay of suppression and enhancement mechanisms in the production of heavy-flavor mesons in the quark-gluon plasma

Measurement of the top quark mass using events with a single reconstructed top quark in pp collisions at s\sqrt{s} = 13 TeV

A measurement of the top quark mass is performed using a data sample enriched with single top quark events produced in the t channel. The study is based on proton- proton collision data, corresponding to an integrated luminosity of 35.9 fb$^{-1}$, recorded at $\sqrt{s}$ = 13 TeV by the CMS experiment at the LHC in 2016. Candidate events are selected by requiring an isolated high-momentum lepton (muon or electron) and exactly two jets, of which one is identified as originating from a bottom quark. Multivariate discriminants are designed to separate the signal from the background. Optimized thresholds are placed on the discriminant outputs to obtain an event sample with high signal purity. The top quark mass is found to be 172.13$^{+0.76}$$_{-0.77}$ GeV, where the uncertainty includes both the statistical and systematic components, reaching sub-GeV precision for the first time in this event topology. The masses of the top quark and antiquark are also determined separately using the lepton charge in the final state, from which the mass ratio and difference are determined to be 0.9952$^{+0.0079}$$_{-0.0104}$ and 0.83$^{+1.79}$$_{-1.35}$ GeV, respectively. The results are consistent with CPT invariance