Programmverifikationssystem Tatzelwurm. Weiterentwicklung während des KORSO-Projekts

Der Bericht enthält eine kurze Darstellung der Entwicklungsarbeiten, die im Rahmen des KORSO-Projekts erfolgt sind. Eine Versionsverwaltung erlaubt den Einsatz des Verifikationssystems während der Programmentwicklungsphase. Zum Beweis der in allen Phasen der Softwareentwicklung anfallenden Verifikations- bedingungen wurde der Beweiser erheblich weiterentwickelt. Der Benutzer hat die Möglichkeit, eigene Beweisregeln zu definieren. Eine Sprache zur Formulierung von Beweisplnen erleichtert die während der Entwicklung von korrekter Software oftmals notwendige Wiederholung von Beweisen. Mit Hilfsmitteln zur Erzeugung von Gegenbeispielen bei unbeweisbaren Formeln erhält der Anwender nützliche Hinweise zur Lokalisierung von Fehlern

NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice

AIMS Endothelial dysfunction is an early step in the development of atherosclerosis. Increased formation of superoxide anions by NADPH oxidase Nox1, 2, and 5 reduces nitric oxide availability and can promote endothelial dysfunction. In contrast, recent evidence supports a vasoprotective role of H2O2 produced by main endothelial isoform Nox4. Therefore, we analysed the impact of genetic deletion of Nox4 on endothelial dysfunction and atherosclerosis in the low-density lipoprotein receptor (Ldlr) knockout model. METHODS AND RESULTS Ex vivo analysis of endothelial function by Mulvany myograph showed impaired endothelial function in thoracic aorta of Nox4(-/-)/Ldlr(-/-) mice. Further progression of endothelial dysfunction due to high-fat diet increased atherosclerotic plaque burden and galectin-3 staining in Nox4(-/-)/Ldlr(-/-) mice compared with Ldlr(-/-) mice. Under physiological conditions, loss of Nox4 does not influence aortic vascular function. In this setting, loss of Nox4-derived H2O2 production could be partially compensated for by nNOS upregulation. Using an innovative optical coherence tomography approach, we were able to analyse endothelial function by flow-mediated vasodilation in the murine saphenous artery in vivo. This new approach revealed an altered flow-mediated dilation in Nox4(-/-) mice, indicating a role for Nox4 under physiological conditions in peripheral arteries in vivo. CONCLUSIONS Nox4 plays an important role in maintaining endothelial function under physiological and pathological conditions. Loss of Nox4-derived H2O2 could be partially compensated for by nNOS upregulation, but severe endothelial dysfunction is not reversible. This leads to increased atherosclerosis under atherosclerotic prone conditions

Технологические решения для реконструкции добывающей скважины глубиной 2170 метров методом зарезки бокового ствола на нефтяном месторождении Томской области

Обоснование технологических решений для реконструкции добывающей скважины глубиной 2170 метров методом зарезки бокового ствола на нефтяном месторождении Томской области. В процессе исследования проводился анализ предоставленных геологических данных для принятия решений при разработке проекта. В результате исследования представлен комплекс технологических решений для строительства бокового ствола. Основные конструктивные, технологические и технико-эксплуатационные характеристики: обоснование и расчет профиля бокового ствола, расчет процессов углубления и заканчивания скважины, определение времени и стоимости проведения работ. Область применения: работа может быть использованы при составлении проектов на скважины, а данные из специальной части – при разработке состава эластомера ВЗД.Substantiation of technological solutions for reconstruction of a production well with a depth of 2,170 meters by the method of sidetracking at an oil field in the Tomsk region. In the course of the study, the analysis of the provided geological data for decision making during project development was carried out. As a result of the research, a set of technological solutions for the construction of the lateral trunk is presented. The main design, technological and technical and operational characteristics: justification and calculation of the sidetrack profile, calculation of the deepening and completion of the well, determination of the time and cost of work. Scope: the work can be used in the design of wells, and data from a special part - when developing the composition of an elastomer

Modeling and generating moving trees from video

We present a probabilistic approach for the automatic production of tree models with convincing 3D appearance and motion. The only input is a video of a moving tree that provides us an initial dynamic tree model, which is used to generate new individual trees of the same type. Our approach combines global and local constraints to construct a dynamic 3D tree model from a 2D skeleton. Our modeling takes into account factors such as the shape of branches, the overall shape of the tree, and physically plausible motion. Furthermore, we provide a generative model that creates multiple trees in 3D, given a single example model. This means that users no longer have to make each tree individually, or specify rules to make new trees. Results with different species are presented and compared to both reference input data and state of the art alternatives

Towards Pervasive Supervision for Autonomic Systems

Abstract One of the key motivations for the provisioning of autonomic communication features in next generation services is to reduce the need of human inference for management tasks. This however means essentially that system control is delegated to the system itself, i.e., the system operator gives up control to a certain extent. The consequence is that autonomic systems might deviate from intended behavior, may show inconsistent or unwanted states and behavior. We propose an approach to develop control structures complementary to distributed, heterogeneous services. We concentrate on necessary properties of those control structures, and furthermore on issues like selfapplicability and self-evolution

Разработка основного оборудования получения металлического лития

Объектом исследования является выпарной аппарат установки получения металлического лития, находящейся в ОАО "НЗХК" (Новосибирский завод химконцентратов). Целью работы были проектирование и исследование выпарного аппарата с центральной циркуляционной трубой и подвесной греющей камерой. Преимущества аппарата с подвесной греющей камерой. Для достижения поставленной цели были решены следующие задачи: анализ конструкций аппаратов; произведен конструктивный и механический расчеты; сравнение полученных расчетов.The object of study is evaporating apparatus unit for production of lithium metal located in the Novosibirsk chemical concentrates plant (Novosibirsk chemical concentrates plant). The aim of this work was the design and study of evaporator with the Central circulation pipe and the suspended heating chamber. The advantages of the apparatus with overhead heating chamber. To achieve this goal have been resolved following tasks: analysis of equipment designs; produced structural and mechanical calculations; comparison of the calculations

Бухгалтерский учет расчетов с персоналом по оплате труда (на примере предприятия HORUS INTERTRADE & CONSULTING)

В данной работе была рассмотрена специфика бухгалтерского учета расчетов с персоналом по оплате труда как в соответствии с российским законодательством, так и с законодательством Республики Узбекистан, дана характеристика организации бухгалтерского учета операций по расчетам с персоналом в узбекской компании ООО "Horus Intertrade & Consulting Kft", предложены меры по ее совершенствованию.In this work, the specifics of the bookkeeping of settlements with employees on remuneration of labor, both in accordance with Russian legislation and with the legislation of the Republic of Uzbekistan, was given, and the characteristics of the organization of accounting for transactions with personnel in the Uzbek company Horus Intertrade & Consulting Kft, Measures for its improvement have been proposed