Design of a single ultra-low-loss magnetic ballast for a wide range of T5 high-efficiency fluorescent lamps

A patent-pending single design of an ultralow-loss (ULL) magnetic ballast for T5 high-efficient (T5-HE) fluorescent lamps rated from 14 to 35 W is presented. Based on the use of a nonlinear physical low-pressure discharge lamp model, it is discovered that the same set of ballast parameters can be chosen for operating T5-HE 14-, 21-, 28-, and 35-W lamps at their respective rated power at a mains voltage in the range of 220-240 V. With energy efficiency higher than and lifetime much longer than their electronic counterparts and being recyclable, the ULL ballasts offer a more environmentally friendly solution to T5-HE lamps than electronic ballasts. This single-ballast design offers great convenience to both ballast manufacturers and users, because only one product design can cover a range of the most popular T5-HE lamps. Both theoretical analysis and experimental results are included to confirm the validity of the proposal. © 2011 IEEE.published_or_final_versio

A "Class-A2" ultra-low-loss magnetic ballast for T5 fluorescent lamps - A new trend for sustainable lighting technology

The high-voltage and low-current features of T5 lamps imply that the copper and core losses of the magnetic ballast can be greatly reduced. This paper shows that magnetic ballasts for high-voltage T5 lamps are not only feasible but their luminous and ballast-loss performance can be better than those of the electronic ballasts. Contrary to common belief, high frequency operation of T5 28 W lamps increases the luminous efficacy by an average of 3.6% only (less than 5%). Practical implementation of an ultra-low-loss magnetic ballast system for T5 28 W lamps is presented. Its total system power is less than the 32 W upper limit specified for Class A2 of energy-efficient electronic ballast for T5 28 W lamps. High-luminous efficacy of 75.63-77.66 lm/W can be achieved. This important breakthrough has the potential of reversing the existing trend of using electronic ballasts as the energy-saving technology in lighting industry. With a better luminous efficacy, lower product and maintenance costs, much longer lifetime, and the use of recyclable metallic materials over its electronic counterparts, this patent-pending proposal provides a truly sustainable lighting solution to the lighting industry. © 2006 IEEE.published_or_final_versio

A "Class-A2" ultra-low-loss magnetic ballast for T5 fluorescent lamps - A new trend for sustainable lighting technology

The high-voltage and low-current features of T5 lamps imply that the copper and core losses of the magnetic ballast can be greatly reduced. This paper shows that magnetic ballasts for high-voltage T5 lamps are not only feasible but their luminous and ballast-loss performance can be better than those of the electronic ballasts. Contrary to common belief, high frequency operation of T5 28 W lamps increases the luminous efficacy by an average of 3.6% only (less than 5%). Practical implementation of an ultra-low-loss magnetic ballast system for T5 28 W lamps is presented. Its total system power is less than the 32 W upper limit specified for Class A2 of energy-efficient electronic ballast for T5 28 W lamps. High-luminous efficacy of 75.63-77.66 lm/W can be achieved. This important breakthrough has the potential of reversing the existing trend of using electronic ballasts as the energy-saving technology in lighting industry. With a better luminous efficacy, lower product and maintenance costs, much longer lifetime, and the use of recyclable metallic materials over its electronic counterparts, this patent-pending proposal provides a truly sustainable lighting solution to the lighting industry. © 2006 IEEE.published_or_final_versio

Weight loss surgery in adolescents corrects high-density lipoprotein subspecies and their function.

Background/objectiveYouth with obesity have an altered high-density lipoprotein (HDL) subspecies profile characterized by depletion of large apoE-rich HDL particles and an enrichment of small HDL particles. The goal of this study was to test the hypothesis that this atherogenic HDL profile is reversible and that HDL function would improve with metabolic surgery.MethodsSerum samples from adolescent males with severe obesity mean±s.d. age of 17.4±1.6 years were studied at baseline and 1 year following vertical sleeve gastrectomy (VSG). HDL subspecies and HDL function were evaluated pre and post VSG using paired t-tests. A lean group of adolescents was included as a reference group.ResultsAfter VSG, body mass index decreased by 32% and insulin resistance as estimated by homeostatic model assessment of insulin resistance decreased by 75% (both P<0.01). Large apoE-rich HDL subspecies increased following VSG (P<0.01) and approached that of lean adolescents despite participants with considerable residual obesity. In addition, HDL function improved compared with baseline (cholesterol efflux capacity increased by 12%, HDL lipid peroxidation potential decreased by 30% and HDL anti-oxidative capacity improved by 25%, all P<0.01).ConclusionsMetabolic surgery results in a significant improvement in the quantity of large HDL subspecies and HDL function. Our data suggest metabolic surgery may improve cardiovascular risk in adolescents and young adults

Epidural Stimulation Induced Modulation of Spinal Locomotor Networks in Adult Spinal Rats

The importance of the in vivo dynamic nature of the circuitries within the spinal cord that generate locomotion is becoming increasingly evident. We examined the characteristics of hindlimb EMG activity evoked in response to epidural stimulation at the S1 spinal cord segment in complete midthoracic spinal cord-transected rats at different stages of postlesion recovery. A progressive and phase-dependent modulation of monosynaptic (middle) and long-latency (late) stimulation-evoked EMG responses was observed throughout the step cycle. During the first 3 weeks after injury, the amplitude of the middle response was potentiated during the EMG bursts, whereas after 4 weeks, both the middle and late responses were phase-dependently modulated. The middle- and late-response magnitudes were closely linked to the amplitude and duration of the EMG bursts during locomotion facilitated by epidural stimulation. The optimum stimulation frequency that maintained consistent activity of the long-latency responses ranged from 40 to 60 Hz, whereas the short-latency responses were consistent from 5 to 130 Hz. These data demonstrate that both middle and late evoked potentials within a motor pool are strictly gated during in vivo bipedal stepping as a function of the general excitability of the motor pool and, thus, as a function of the phase of the step cycle. These data demonstrate that spinal cord epidural stimulation can facilitate locomotion in a time-dependent manner after lesion. The long-latency responses to epidural stimulation are correlated with the recovery of weight-bearing bipedal locomotion and may reflect activation of interneuronal central pattern-generating circuits

Intrusion detection routers: Design, implementation and evaluation using an experimental testbed

In this paper, we present the design, the implementation details, and the evaluation results of an intrusion detection and defense system for distributed denial-of-service (DDoS) attack. The evaluation is conducted using an experimental testbed. The system, known as intrusion detection router (IDR), is deployed on network routers to perform online detection on any DDoS attack event, and then react with defense mechanisms to mitigate the attack. The testbed is built up by a cluster of sufficient number of Linux machines to mimic a portion of the Internet. Using the testbed, we conduct real experiments to evaluate the IDR system and demonstrate that IDR is effective in protecting the network from various DDoS attacks. © 2006 IEEE.published_or_final_versio

Prenatal Detection of Aneuploidy and Imbalanced Chromosomal Arrangements by Massively Parallel Sequencing

Fetal chromosomal abnormalities are the most common reasons for invasive prenatal testing. Currently, G-band karyotyping and several molecular genetic methods have been established for diagnosis of chromosomal abnormalities. Although these testing methods are highly reliable, the major limitation remains restricted resolutions or can only achieve limited coverage on the human genome at one time. The massively parallel sequencing (MPS) technologies which can reach single base pair resolution allows detection of genome-wide intragenic deletions and duplication challenging karyotyping and microarrays as the tool for prenatal diagnosis. Here we reported a novel and robust MPS-based method to detect aneuploidy and imbalanced chromosomal arrangements in amniotic fluid (AF) samples. We sequenced 62 AF samples on Illumina GAIIx platform and with averagely 0.01× whole genome sequencing data we detected 13 samples with numerical chromosomal abnormalities by z-test. With up to 2× whole genome sequencing data we were able to detect microdeletion/microduplication (ranged from 1.4 Mb to 37.3 Mb of 5 samples from chorionic villus sampling (CVS) using SeqSeq algorithm. Our work demonstrated MPS is a robust and accurate approach to detect aneuploidy and imbalanced chromosomal arrangements in prenatal samples

Genetic Structure of the Tree Peony (Paeonia rockii) and the Qinling Mountains as a Geographic Barrier Driving the Fragmentation of a Large Population

Tree peonies are great ornamental plants associated with a rich ethnobotanical history in Chinese culture and have recently been used as an evolutionary model. The Qinling Mountains represent a significant geographic barrier in Asia, dividing mainland China into northern (temperate) and southern (semi-tropical) regions; however, their flora has not been well analyzed. In this study, the genetic differentiation and genetic structure of Paeonia rockii and the role of the Qinling Mountains as a barrier that has driven intraspecific fragmentation were evaluated using 14 microsatellite markers.Twenty wild populations were sampled from the distributional range of P. rockii. Significant population differentiation was suggested (F(ST) value of 0.302). Moderate genetic diversity at the population level (H(S) of 0.516) and high population diversity at the species level (H(T) of 0.749) were detected. Significant excess homozygosity (F(IS) of 0.076) and recent population bottlenecks were detected in three populations. Bayesian clusters, population genetic trees and principal coordinate analysis all classified the P. rockii populations into three genetic groups and one admixed Wenxian population. An isolation-by-distance model for P. rockii was suggested by Mantel tests (r = 0.6074, P<0.001) and supported by AMOVA (P<0.001), revealing a significant molecular variance among the groups (11.32%) and their populations (21.22%). These data support the five geographic boundaries surrounding the Qinling Mountains and adjacent areas that were detected with Monmonier's maximum-difference algorithm.Our data suggest that the current genetic structure of P. rockii has resulted from the fragmentation of a formerly continuously distributed large population following the restriction of gene flow between populations of this species by the Qinling Mountains. This study provides a fundamental genetic profile for the conservation and responsible exploitation of the extant germplasm of this species and for improving the genetic basis for breeding its cultivars