6 research outputs found
Evaluation nationale des pratiques de prise en charge préhospitaliÚre des traumatisés vertébro-médullaires
DIJON-BU MĂ©decine Pharmacie (212312103) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF
Subretinal drusenoid deposits in an elderly population with age-related macular degeneration (MONTRACHET study: Maculopathy, Optic Nerve, nuTRition, neurovasCular and HEarT diseases)
National audiencePurpose To determine the frequency of subretinal drusenoid deposits (SDD) in a French population of elderly patients presenting an ageârelated macular degeneration (AMD) in the MONTRACHET study. Methods The threeâcity study (3C) was a populationâbased study including 9294 patients older than 65 years from three French cities (Dijon, Bordeaux and Montpellier) at baseline in 1999. After 10 years, the cohort of Dijon benefited from a complete ophthalmologic examination as part of the MONTRACHET study. Each patient underwent a nonâmydriatic retinophotography associated with a spectralâdomain OCT examination (SDâOCT) of the macula. AMD classification was established according to the classification of the MultiâEthnic study of Atherosclerosis (MESA) for the retinophotography analysis and with the E3 CONSORTIUM classification for the SDâOCT analysis. Patients with uninterpretable images of both eyes were excluded from statistical analysis. Results One thousand one hundred fifty three subjects were included. 62.7% were female and the mean age was 82.2 ± 3.8 years. With retinophotography analysis, the frequency of SDD was 1.9% (n = 38 eyes). With the SDâOCT macular analysis, the frequency of SDD was 14.8% (n = 342). In patients presenting with SDD, 68.8% (n = 137) had a bilateral involvement. The relative risk (RR) of presenting SDD lesions in patients older than 80 years old was 2.6 (p < 0.001) and in women at 1.3 (p < 0.045). An interruption of the ellipsoide line and an alteration of the retinal pigment epithelium were statistically associated with the presence of SDD: RR = 5.9 (p < 0.001) and RR = 2.8 (p < 0.001), respectively. The average thickness of the subfoveal choroid was thinner in subjects presenting SDD (174.9 ÎŒm with SDD vs 209.8 ÎŒm without SDD, p < 0.001). Conclusions Few populationâbased studies have established the frequency of SDD in an elderly population
Large-vessel vasculitis diagnosed between 50 and 60âŻyears: Case-control study based on 183 cases and 183 controls aged over 60âŻyears
International audienceAge at onset of large-vessel vasculitis (LVV) is commonly used to distinguish giant cell arteritis (GCA) and Takayasu arteritis (TA). However, LVV between age 50 and 60âŻyears may be difficult to classify