Bio-inspired Networking: analisi della letteratura applicata al modello MoK

Scopo della tesi è quello di esplorare la letteratura in cerca di alternative applicabili rispetto agli approcci tradizionali per quanto riguarda la comunicazione nei sistemi distributi, specialmente nel caso di reti p2p con network altamente dinamiche, derivate da paradigmi bio-inspired. In particolare verranno analizzati i requisiti di MoK, un modello per la coordinazione di agenti software basato sulla distribuzione di informazioni in rete, e verranno isolate delle proprietà che possiamo ritenere adatte a risolvere le problematiche attaccate da tale modello, per poi ricercare determinati algoritmi, meccanismi e processi che dispongano di tali proprietà per soddisfare i requisiti di Mok

RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product

Here, we show that the subcellular localization of α-like RNA polymerase II core subunit 3 (RPB3) is regulated during muscle differentiation. We have recently demonstrated that the expression of RPB3 is regulated during muscle differentiation and that, inside RNA polymerase II (RNAP II), it is directly involved in contacting regulatory proteins such as the myogenic transcription factor Myogenin and activating transcription factor ATF4. We show for the first time, that RPB3, in addition to its presence and role inside the RNAP II core enzyme, accumulates in the cytoplasm of cycling myogenic cells and migrates to the nucleus upon induction of the differentiation program. Furthermore, using human RPB3 as bait in a yeast two-hybrid system, we have isolated a novel RPB3 cytoplasmic interacting protein, HCR. HCR, previously identified as α-helix coiled-coil rod homologue, is one of the psoriasis vulgaris (PV) candidate genes. In cycling myogenic C2C7 cells, we show that the RPB3 protein directly interacts with HCR within the cytoplasm. Finally, knocking down HCR expression by RNA interference, we demonstrate that HCR acts as cytoplasmic docking site for RPB3

A Review of Basic Mechanical Behavior of Laminated Bamboo Lumber

Over the past decade, the physical and mechanical performances of laminated bamboo lumber (LBL)–a bamboobased structural material, have been extensively studied using experimental, analytical, and numerical approaches. This paper presents a review of existing knowledge in the literature about the mechanical properties of LBL. The paper involved the review of the response of LBL to different types of loading such as tension, bending, compression, and shear. Based on results of the literature reviewed, the strength of LBL parallel to grain was 90–124 MPa with MOE of 10700 MPa in tension, 29.55–72.60 MPa, and MOE of 8396–11022 MPa in compression, 63.87– 128.4 MPa, and MOE of 8320–10912 MPa in bending, and 7.15–17.5 MPa in shear. The average strength of LBL was similar and in some cases exceeded the average values of bamboo- or wood-based materials, while the variability of its mechanical parameters was lower. The variability in strength values of LBL was affected by bamboo species, density and thickness of bamboo strips, growth portion, type of treatment, strips arrangements, and type of adhesive which in turn calls for classification of LBL by strength grades, degree of hardness, the capability of impregnation and penetration, as well as by areas of application in construction. The study provided and discussed concluding observations, the current research gap, and future research directions on the mechanical properties of LBL

The components of economic freedom, income and growth: an empirical analysis

This paper seeks to bring a better understanding of the relationship between economic growth and the disaggregated factors which constitute the elements of economic freedom. The two main objectives of this paper are to: (1) based on the Solow augmented growth model, test which of the elements of economic freedom demonstrate a statistically significant relationship to economic growth; and (2) establish which way the main causality direction between economic freedom and growth runs from. Finally, we identify desirable directions for further research and policy implications.Este artigo procura trazer um melhor entendimento da relação entre crescimento econômico e os fatores que constituem os elementos da liberdade econômica. Os dois principais objetivos do artigo são: (1) baseados no modelo neoclássico aumentado de crescimento, testar quais dos elementos componentes da liberdade econômica demonstram ter uma relação estatisticamente significante com crescimento; e (2) estabelecer para que lado ocorre a principal direção de causalidade entre liberdade econômica e crescimento. Finalmente, nós identificamos direções desejáveis para novas pesquisas e implicações para política econômica

Moral emotions, principles, and the locus of moral perception

I vindicate the thrust of the particularist position in moral deliberation. this purpose, I focus on some elements that seem to play a crucial role in first-person moral deliberation and argue that they cannot be incorporated into a more sophisticated system of moral principles. More specifically, I emphasize some peculiarities of moral perception in the light of which I defend the irreducible deliberative relevance of a certain phenomenon, namely: the phenomenon of an agent morally coming across a particular situation. Following on from Bbernard Williams, I talk of an agent’s character as a factor that contributes to fixing what situations an agent comes morally across. A crucial point, in the debate, will be how an agent confronts the normatively loaded features of his own character when he is engaged in first-person deliberation

Review of Current Student-Monitoring Techniques used in eLearning-Focused recommender Systems and Learning analytics. The Experience API & LIME model Case Study

Recommender systems require input information in order to properly operate and deliver content or behaviour suggestions to end users. eLearning scenarios are no exception. Users are current students and recommendations can be built upon paths (both formal and informal), relationships, behaviours, friends, followers, actions, grades, tutor interaction, etc. A recommender system must somehow retrieve, categorize and work with all these details. There are several ways to do so: from raw and inelegant database access to more curated web APIs or even via HTML scrapping. New server-centric user-action logging and monitoring standard technologies have been presented in past years by several groups, organizations and standard bodies. The Experience API (xAPI), detailed in this article, is one of these. In the first part of this paper we analyse current learner-monitoring techniques as an initialization phase for eLearning recommender systems. We next review standardization efforts in this area; finally, we focus on xAPI and the potential interaction with the LIME model, which will be also summarized below

Natural Disasters and Preferences for the Environment: Evidence from the Impressionable Years

Do generations affected by natural disasters during the critical years of adolescence and early adulthood form different preferences towards the environment than generations who are not? Consistent with the theories of social psychology, we show that an environmental shock experienced during the impressionable years (18-25 years old) help shape positive environmental preferences. Individuals tend not to change beliefs in response to natural disasters experienced in other age ranges. Using information from the General Social Survey and World Values Survey, we exploit yearly natural disasters variation both within the US and across countries to identify these effects

Fiber alignment angles effect on the tensile performance of laminated bamboo lumber

For better application of laminated bamboo lumber (LBL) in construction industry, the tensile performance of LBL was studied by conducting tension test on LBL specimens with seven different fiber alignment angles, each alignment angle containing 30 specimens. All the specimens only experienced the elastic stage before brittle failure with four failure types. With increasing alignment angle, the tensile strength, tensile modulus, and ultimate tension strain decreased rapidly from 0° to 30°, while they almost remained constant after the angle of 45°. Hankinson’s formula (n = 1.75) can be used to predict the tensile strength of LBL. An empirical equation was proposed to predict the tensile modulus of LBL. The Poisson’s ratio increased and peaked at 15° before declining. Based on the stress–strain coordinate transformation, the relation between shear properties and the alignment angle of LBL was studied; the calculated shear strength decreased with increasing alignment angle, and an empirical equation was proposed, which could be used to obtain the shear strength of LBL for engineering use

La deriva della ‘learnification’ e l’appello della paideía Oltre l’apprendimento ‘matematico’ e costruttivista

Prendendo le mosse dalla nozione di learnification, intesa, con Gert Biesta, come la prevalenza del linguaggio dell’apprendimento su quello dell’educazione nel discorso pedagogico dell’ultimo trentennio, l’articolo argomenta che tale enfasi sull’apprendimento sia stato uno dei motivi dell’egemonia del paradigma costruttivista nelle pratiche educative e mira a individuare un orizzonte possibile di ripensamento del costruttivismo alla luce di un recupero dell’idea di paideía, nella declinazione particolare a essa conferita da Heidegger. Proprio da un confronto fra la riflessione sull’educazione di Heidegger (con il privilegiamento della intenzionalità originaria, del nesso alétheia-paideía, di una specifica interpretazione del Verstehen) e la proposta pedagogica di von Glasersfeld (di cui si palesano i rischi solipsistici e la solidarietà col progetto matematico della modernità), l’articolo disegna il profilo di una ‘paideía pragmatica’ che consenta tanto di superare alcune oltranze del costruttivismo quanto di collocare in una giusta prospettiva i recenti richiami ‘alla realtà’ presenti nel dibattito teorico internazionale

Experimental and numerical study on eccentric compression properties of laminated bamboo columns with a chamfered section

The eccentric compression behavior of laminated bamboo lumber (LBL) columns with a chamfered section was investigated using eccentricity of 30 mm, 60 mm, 90 mm and 120 mm. The effect of eccentricity ratio on the ultimate bearing capacity, ultimate strain and failure mode was analyzed through eccentric compression tests. The failure modes of LBL columns with different eccentricities were basically same, which belonged to brittle tension failure. With the increase in eccentricity ratio, the ultimate bearing capacity and ultimate strain gradually decreased. The cross-section strain of the specimen was linearly distributed along the height direction, which conformed to the plane section assumption. The lateral deflection curves had similar characteristics under different load levels and could be expressed by sine half-wave curves. Based on the Hill failure criterion, a 3D finite element model was developed to calculate the ultimate bearing capacity of LBL columns with different dimensions under eccentric compression. According to the simulation results and test results, a general empirical formula was proposed considering both the influence of slenderness ratio and eccentricity ratio. The reliability of the proposed formula was verified by comparing the calculated results with the results in the existing literature