511 research outputs found

    Exploring the Decision Making Processes of Early Career Strength and Conditioning Coaches

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    The role of Strength and Conditioning coaches within sporting environments is growing in importance and more attention is being directed towards acknowledging the characteristics and decision making processes of these coaches.  To date, most of the research has been with experienced coaches thus created a need to better understand those coaches at the early stages of their career.  The present study utilised Applied Cognitive Task Analysis to elicit knowledge from eight strength and conditioning coaches with less than three years full time experience.  Methods applied identified that less experienced strength and conditioning coaches operate in predominately stable conditions and feel comfortable delivering within this stability. Interviews revealed early career coaches to prioritise movement qualities and rely on previously acquired theoretical knowledge to make predetermined decisions on training content and responses within environments.  A final theme generated demonstrated that connections with athletes were important for coaches to feel confident within their role.  Implications for future coach development materials exploring the use of metacognition and its associated components of planning, monitoring and evaluation discussed

    Hadron mass corrections in semi-inclusive deep inelastic scattering

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    We derive mass corrections for semi-inclusive deep inelastic scattering of leptons from nucleons using a collinear factorization framework which incorporates the initial state mass of the target nucleon and the final state mass of the produced hadron. The formalism is constructed specifically to ensure that physical kinematic thresholds for the semi-inclusive process are explicitly respected. A systematic study of the kinematic dependencies of the mass corrections to semi-inclusive cross sections reveals that these are even larger than for inclusive structure functions, especially at very small and very large hadron momentum fractions. The hadron mass corrections compete with the experimental uncertainties at kinematics typical of current facilities, and will be important to efforts at extracting parton distributions or fragmentation functions from semi-inclusive processes at intermediate energies.Comment: 22 pages, 6 figures; expanded discussion of kinematics and new scaling variable; appendix comparing collinear frames included; version to appear in JHE

    Setting the stage for individualized therapy in hemophilia: what role can pharmacokinetics play?

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    Replacement therapy with clotting factor concentrates (CFC) is the mainstay of treatment in hemophilia. Its widespread application has led to a dramatic decrease in morbidity and mortality in patients, with concomitant improvement of quality of life. However, dosing is challenging and costs are high. This review discusses benefits and limitations of pharmacokinetic (PK)-guided dosing of replacement therapy as an alternative for current dosing regimens. Dosing of CFC is now primarily based on body weight and based on its in vivo recovery (IVR). Benefits of PK-guided dosing include individualization of treatment with better targeting, more flexible blood sampling, increased insight into association of coagulation factor levels and bleeding, and potential overall lowering of overall costs. Limitations include a slight burden for the patient, and availability of closely collaborating, experienced clinical pharmacologists

    Weak multiplicativity for random quantum channels

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    It is known that random quantum channels exhibit significant violations of multiplicativity of maximum output p-norms for any p>1. In this work, we show that a weaker variant of multiplicativity nevertheless holds for these channels. For any constant p>1, given a random quantum channel N (i.e. a channel whose Stinespring representation corresponds to a random subspace S), we show that with high probability the maximum output p-norm of n copies of N decays exponentially with n. The proof is based on relaxing the maximum output infinity-norm of N to the operator norm of the partial transpose of the projector onto S, then calculating upper bounds on this quantity using ideas from random matrix theory.Comment: 21 pages; v2: corrections and additional remark

    Treatment regimens and outcomes in severe and moderate haemophilia A in the UK: The THUNDER study

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    Introduction: The THUNDER study provides an analysis of treatment patterns and outcomes in UK patients with severe or moderate haemophilia A (SHA/MHA) in 2015. Methods: Patients with SHA or MHA registered with the UK National Haemophilia Database (NHD) were segregated by severity, inhibitor status and age. Haemophilia joint health score (HJHS) was derived from NHD records and treatment regimen and annualized bleed/joint‐bleed rate (ABR/AJBR) from Haemtrack (HT) in HT‐compliant patients. Results: We report 1810 patients with SHA and 864 with MHA. Prophylaxis was used in 94.9% (n = 130/137) of HT‐compliant children <12 years with SHA, falling to 74.1% (n = 123/166) aged ≥40 years. Median ABR increased with age (1.0, IQR 0.0‐5.0, <12 years; 3.0 IQR, 1.0‐8.0, ≥40 years). Inhibitors were present in 159 (8.8%) SHA and 34 (3.9%) MHA. Median ABR increased from 2.0 (<12 years) to 21.(≥40 years) in SHA inhibitor patients using prophylaxis. Prophylaxis was used by 68.8% of HT‐compliant MHA patients (n = 106) (median FVIII baseline 0.01 IU/mL) associated with a median (IQR) ABR of 3.0 (1.0‐7.0). Median HJHS (n = 453) increased with age in SHA and MHA. Median (IQR) HJHS was higher in SHA inhibitor (17.0, 0.0‐64.5) than non‐ or past inhibitor patients (7.0, 0.0‐23.0). Conclusions: Increasing ABR with age persists despite current prophylaxis regimens.SHA and MHA had similar ABR/AJBR and HJHS, leading to a suspicion that a subgroup of MHA may be relatively undertreated. More intensive prophylaxis may improve outcomes, but this requires further study

    Next-to-leading Corrections to the Higgs Boson Transverse Momentum Spectrum in Gluon Fusion

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    We present a fully analytic calculation of the Higgs boson transverse momentum and rapidity distributions, for nonzero Higgs pp_\perp, at next-to-leading order in the infinite-top-mass approximation. We separate the cross section into a part that contains the dominant soft, virtual, collinear, and small-pp_\perp-enhanced contributions, and the remainder, which is organized by the contributions due to different parton helicities. We use this cross section to investigate analytically the small-pp_\perp limit and compare with the expectation from the resummation of large logarithms of the type lnmH/p\ln{m_H/p_\perp}. We also compute numerically the cross section at moderate pp_\perp where a fixed-order calculation is reliable. We find a KK-factor that varies from 1.61.8\approx1.6-1.8, and a reduction in the scale dependence, as compared to leading order. Our analysis suggests that the contribution of current parton distributions to the total uncertainty on this cross section at the LHC is probably less than that due to uncalculated higher orders.Comment: 40 pages, 10 figures, JHEP style (minor changes, added reference

    Anisotropic optical properties of single-crystal GdBa2Cu3O7-delta

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    The optical spectrum of reduced-T(c) GdBa2Cu3O7-delta has been measured for polarizations parallel and perpendicular to the ab plane. The sample was an oxygen-deficient single crystal with a large face containing the c axis. The polarized reflectance from this face was measured from 20-300 K in the spectral region from 30-3000 cm-1, with 300 K data to 30 000 cm-1. Kramers-Kronig analysis was used to determine the spectral dependence of the ab and the c components of the dielectric tensor. The optical properties are strongly anisotropic. The ab-plane response resembles that of other reduced-T(c) materials whereas the c axis, in contrast, shows only the presence of several phonons. There is a complete absence of charge carrier response along c above and below T(c). This observation allows us to set an upper limit to the free-carrier spectral weight for transport perpendicular to the CuO2 planes

    The UKIDSS Galactic Plane Survey

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    'The definitive version is available at www.blackwell-synergy.com .' Copyright Blackwell Publishing DOI: 10.1111/j.1365-2966.2008.13924.xThe UKIDSS Galactic Plane Survey (GPS) is one of the five near-infrared Public Legacy Surveys that are being undertaken by the UKIDSS consortium, using the Wide Field Camera on the United Kingdom Infrared TelescopePeer reviewe

    Phase-Field Approach for Faceted Solidification

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    We extend the phase-field approach to model the solidification of faceted materials. Our approach consists of using an approximate gamma-plot with rounded cusps that can approach arbitrarily closely the true gamma-plot with sharp cusps that correspond to faceted orientations. The phase-field equations are solved in the thin-interface limit with local equilibrium at the solid-liquid interface [A. Karma and W.-J. Rappel, Phys. Rev. E53, R3017 (1996)]. The convergence of our approach is first demonstrated for equilibrium shapes. The growth of faceted needle crystals in an undercooled melt is then studied as a function of undercooling and the cusp amplitude delta for a gamma-plot of the form 1+delta(|sin(theta)|+|cos(theta)|). The phase-field results are consistent with the scaling law "Lambda inversely proportional to the square root of V" observed experimentally, where Lambda is the facet length and V is the growth rate. In addition, the variation of V and Lambda with delta is found to be reasonably well predicted by an approximate sharp-interface analytical theory that includes capillary effects and assumes circular and parabolic forms for the front and trailing rough parts of the needle crystal, respectively.Comment: 1O pages, 2 tables, 17 figure
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