143 research outputs found

    Analisis Yuridis terhadap Perjanjian Tertutup yang Dilakukan oleh PT. Pelabuhan Indonesia II (Persero) di Pelabuhan Teluk Bayur Sumatera Barat (Studi Kasus terhadap Putusan Perkara Nomor 02/kppu-i/2013)

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    An enclosed field of business law is the field of anti- monopoly and antitrust (competition). Law defines a monopoly as a mastery and or marketing of goods or the use of certain services by 1 businesses or one group of business actors. Thus , according to the legislation of the Anti- Monopoly with monopolistic practices are intended as a concentration of economic power by one or more businesses that resulted in control of the production and or marketing of goods and or services giving rise to an unhealthy competition and can harm the public interest . Based on the Commission \u27s decision No. 02 / KPPU - 01 / 2013 Teluk Bayur otherwise violate Article 15, Paragraph 2 of the Constitution of 1999 on Monopolistic Practices and Unfair Competition . Teluk Bayur decided violates the provisions of law for committing a closed agreement with the tenants in Teluk Bayur, which cause unfair competition among businesses that are unloading Teluk Bayur Ports , because they block the loading and unloading of other businesses

    On the eigenvalues of Cayley graphs on the symmetric group generated by a complete multipartite set of transpositions

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    Given a finite simple graph \cG with nn vertices, we can construct the Cayley graph on the symmetric group SnS_n generated by the edges of \cG, interpreted as transpositions. We show that, if \cG is complete multipartite, the eigenvalues of the Laplacian of \Cay(\cG) have a simple expression in terms of the irreducible characters of transpositions, and of the Littlewood-Richardson coefficients. As a consequence we can prove that the Laplacians of \cG and of \Cay(\cG) have the same first nontrivial eigenvalue. This is equivalent to saying that Aldous's conjecture, asserting that the random walk and the interchange process have the same spectral gap, holds for complete multipartite graphs.Comment: 29 pages. Includes modification which appear on the published version in J. Algebraic Combi

    Griffiths singularities in the two dimensional diluted Ising model

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    We study numerically the probability distribution of the Yang-Lee zeroes inside the Griffiths phase for the two dimensional site diluted Ising model and we check that the shape of this distribution is that predicted in previous analytical works. By studying the finite size scaling of the averaged smallest zero at the phase transition we extract, for two values of the dilution, the anomalous dimension, η\eta, which agrees very well with the previous estimated values.Comment: 11 pages and 4 figures, some minor changes in Fig. 4, available at http://chimera.roma1.infn.it/index_papers_complex.htm

    Rapid Mixing for Lattice Colorings with Fewer Colors

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    We provide an optimally mixing Markov chain for 6-colorings of the square lattice on rectangular regions with free, fixed, or toroidal boundary conditions. This implies that the uniform distribution on the set of such colorings has strong spatial mixing, so that the 6-state Potts antiferromagnet has a finite correlation length and a unique Gibbs measure at zero temperature. Four and five are now the only remaining values of q for which it is not known whether there exists a rapidly mixing Markov chain for q-colorings of the square lattice.Comment: Appeared in Proc. LATIN 2004, to appear in JSTA

    Implicazioni geodinamiche delle recenti misure geodetiche nello Stretto di Messina

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    Il 28 dicembre 1908 lo Stretto di Messina veniva colpito da un disastroso evento sismico di ms=7.5. L'evento è il più forte tra i terremoti italiani degli utimi 100 anni.Published3-143.3. Geodinamica e struttura dell'interno della TerraN/A or not JCRrestricte

    Smeared phase transition in a three-dimensional Ising model with planar defects: Monte-Carlo simulations

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    We present results of large-scale Monte Carlo simulations for a three-dimensional Ising model with short range interactions and planar defects, i.e., disorder perfectly correlated in two dimensions. We show that the phase transition in this system is smeared, i.e., there is no single critical temperature, but different parts of the system order at different temperatures. This is caused by effects similar to but stronger than Griffiths phenomena. In an infinite-size sample there is an exponentially small but finite probability to find an arbitrary large region devoid of impurities. Such a rare region can develop true long-range order while the bulk system is still in the disordered phase. We compute the thermodynamic magnetization and its finite-size effects, the local magnetization, and the probability distribution of the ordering temperatures for different samples. Our Monte-Carlo results are in good agreement with a recent theory based on extremal statistics.Comment: 9 pages, 6 eps figures, final version as publishe

    Percolation transition and the onset of non exponential relaxation in fully frustrated models

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    We numerically study the dynamical properties of fully frustrated models in 2 and 3 dimensions. The results obtained support the hypothesis that the percolation transition of the Kasteleyn-Fortuin clusters corresponds to the onset of stretched exponential autocorrelation functions in systems without disorder. This dynamical behavior may be due to the ``large scale'' effects of frustration, present below the percolation threshold. Moreover these results are consistent with the picture suggested by Campbell et al. in space of configurations.Comment: 8 pages, 11 figures, revised versio

    Effective delivery of large genes to the retina by dual AAV vectors.

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    Retinal gene therapy with adeno-associated viral (AAV) vectors is safe and effective in humans. However, AAV's limited cargo capacity prevents its application to therapies of inherited retinal diseases due to mutations of genes over 5 kb, like Stargardt's disease (STGD) and Usher syndrome type IB (USH1B). Previous methods based on "forced" packaging of large genes into AAV capsids may not be easily translated to the clinic due to the generation of genomes of heterogeneous size which raise safety concerns. Taking advantage of AAV's ability to concatemerize, we generated dual AAV vectors which reconstitute a large gene by either splicing (trans-splicing), homologous recombination (overlapping), or a combination of the two (hybrid). We found that dual trans-splicing and hybrid vectors transduce efficiently mouse and pig photoreceptors to levels that, albeit lower than those achieved with a single AAV, resulted in significant improvement of the retinal phenotype of mouse models of STGD and USH1B. Thus, dual AAV trans-splicing or hybrid vectors are an attractive strategy for gene therapy of retinal diseases that require delivery of large gene

    The Potts Fully Frustrated model: Thermodynamics, percolation and dynamics in 2 dimensions

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    We consider a Potts model diluted by fully frustrated Ising spins. The model corresponds to a fully frustrated Potts model with variables having an integer absolute value and a sign. This model presents precursor phenomena of a glass transition in the high-temperature region. We show that the onset of these phenomena can be related to a thermodynamic transition. Furthermore this transition can be mapped onto a percolation transition. We numerically study the phase diagram in 2 dimensions (2D) for this model with frustration and {\em without} disorder and we compare it to the phase diagram of i)i) the model with frustration {\em and} disorder and of ii)ii) the ferromagnetic model. Introducing a parameter that connects the three models, we generalize the exact expression of the ferromagnetic Potts transition temperature in 2D to the other cases. Finally, we estimate the dynamic critical exponents related to the Potts order parameter and to the energy.Comment: 10 pages, 10 figures, new result

    In vitro chronic administration of ERbeta selective ligands and prostate cancer cell growth : hypotheses on the selective role of 3beta-adiol in AR-positive RV1 cells

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    Prostate cancer (PC) progression from androgen-dependent (AD) to castration-resistant (CR) disease is a process caused by modifications of different signal transduction pathways within tumor microenvironment. Reducing cell proliferation, estrogen receptor beta (ERbeta) is emerging as a potential target in PC chemoprevention. Among the known selective ERbeta ligands, 3beta-Adiol, the endogenous ligand in the prostate, has been proved to counteract PC progression. This study compares the effects of chronic exposure (1-12 weeks) to different ERbeta selective ligands (DPN, 8beta-VE2, 3beta-Adiol) on proliferation of human androgen-responsive CWR22Rv1 cells, representing an intermediate phenotype between the AD- and CR-PC. 3beta-Adiol (10 nM) is the sole ligand decreasing cell proliferation and increasing p21 levels. In vitro transcriptional activity assays were performed to elucidate different behavior between 3beta-Adiol and the other ligands; in these experiments the endogenous and the main ERbeta subtype activation were considered. It is concluded that ERbeta activation has positive effects also in androgen-responsive PC. The underlying mechanisms are still to be clarified and may include the interplay among different ERbeta subtypes and the specific PC microenvironment. ERbeta agonists might be useful in counteracting PC progression, although the final outcome may depend upon the molecular pattern specific to each PC lesion
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