8,053 research outputs found
Simulating the onset and spread of anoxic conditions during Cretaceous OAE2
A new model of the global atmosphere-ocean-continent-mantle system was set-up to investigate the triggering of the Oceanic Anoxic Event OAE2 through volcanic degassing processes at large igneous provinces (LIPs). The model simulates the changes in oceanic dissolved oxygen, phosphate, and carbon and the evolution of atmospheric
pCO2 values under mid-Cretaceous boundary conditions. It considers the effects of pCO2 on element ratios in marine plankton (C : P) and includes new parameterizations for phosphorus and carbon burial at the seafloor based on modern observations. Independent isotopic and chemical time-series of ocean and atmosphere change over OAE2 are applied to evaluate the model results. The model results support the hypothesis that OAE2 was triggered by massive CO2 emissions at LIPs. According to the model, the phosphorus weathering flux into the ocean and the C : P ratio in marine plankton were enhanced by the rise in surface temperature and atmosphere pCO2 caused by mantle degassing. Marine export production and oxygen consumption in intermediate and deep water masses increased in response to the expansion of the dissolved phosphate inventory of the ocean and the change in plankton element ratios. The spread of anoxic conditions in bottom waters -induced by enhanced carbon export and respiration- was further amplified by the oxygen-dependent burial of phosphorus in marine sediments in a positive feedback loop. The modeling implies that enhanced CO2 emissions favor the spread of low-oxygen conditions also in modern oceans
Detecting groundwater discharge dynamics from point-to-catchment scale in a lowland stream : Combining hydraulic and tracer methods
Acknowledgements. We would like to thank members of the Northern Rivers Institute, Aberdeen University, for helpful discussions of data. We also thank Lars Rasmussen, Jolanta Kazmierczak and Charlotte Ditlevsen for help in the field. This study is part of the Hydrology Observatory, HOBE (http://www.hobe.dk), funded by the Villum Foundation and was as well funded by the Aarhus University Research Foundation.Peer reviewedPublisher PD
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A genome-wide association study reveals specific transferases as candidate loci for bovine milk oligosaccharides synthesis.
BackgroundHuman milk oligosaccharides (OS) play a key role in brain and gut microbiota development of the neonate, but the underlying biosynthetic steps of OS in the mammary gland are still largely unknown. As bovine milk contains OS with somewhat similar structures and functionalities there is increased interest in further understanding the genetic basis underlying the OS content of milk for eventual extraction and generation of value-added ingredients for infant formulas and nutraceuticals. The present study is the first to report on genetic parameter estimation as well as on a genome wide association study (GWAS) from the largest bovine milk OS dataset analyzed to date.ResultsIn total 15 different bovine milk OS were monitored. Heritabilities ranged from 0 to 0.68 in Danish Holstein and from 0 to 0.92 in Danish Jersey. The GWAS identified in total 1770 SNPs (FDRâ<â0.10) for five different OS in Danish Holstein and 6913 SNPs (FDRâ<â0.10) for 11 OS in Danish Jersey. In Danish Holstein, a major overlapping QTL was identified on BTA1 for LNH and LNT explaining 24% of the variation in these OS. The most significant SNPs were associated with B3GNT5, a gene encoding a glycosyltransferase involved in glycan synthesis. In Danish Jersey, a very strong QTL was detected for the OS with composition 2 Hex 1 HexNAc (isomer 1) on BTA11. The most significant SNP had -log10(P-value) of 52.88 (BOVINEHD1100030300) and was assigned to ABO, a gene encoding ABO blood group glycosyltransferases. This SNP has been reported to be a missense mutation and explains 56% of the OS variation. Other candidate genes of interest identified for milk OS were ALG3, B3GALNT2, LOC520336, PIGV, MAN1C1, ST6GALNAC6, GLT6D1, GALNT14, GALNT17, COLGALT2, LFNG and SIGLEC.ConclusionTo our knowledge, this is the first study documenting a solid breeding potential for bovine milk OS and a strong indication of specific candidate genes related to OS synthesis underlying this genetic influence. This new information has the potential to guide breeding strategies to achieve production of milk with higher diversity and concentration of OS and ultimately facilitate large-scale extraction of bovine milk OS
EEG in the classroom: Synchronised neural recordings during video presentation
We performed simultaneous recordings of electroencephalography (EEG) from
multiple students in a classroom, and measured the inter-subject correlation
(ISC) of activity evoked by a common video stimulus. The neural reliability, as
quantified by ISC, has been linked to engagement and attentional modulation in
earlier studies that used high-grade equipment in laboratory settings. Here we
reproduce many of the results from these studies using portable low-cost
equipment, focusing on the robustness of using ISC for subjects experiencing
naturalistic stimuli. The present data shows that stimulus-evoked neural
responses, known to be modulated by attention, can be tracked in for groups of
students with synchronized EEG acquisition. This is a step towards real-time
inference of engagement in the classroom.Comment: 14 pages, 5 figures, 3 tables. Preprint version. Revision of original
preprint. Supplementary materials added as ancillary fil
Profiling of aminoxyTMT-labeled bovine milk oligosaccharides reveals substantial variation in oligosaccharide abundance between dairy cattle breeds.
Free milk oligosaccharides are bioactive molecules that function as prebiotics and prevent infections that commonly afflict developing infants. To date, few publications have examined the factors affecting bovine milk oligosaccharide production among cattle in the dairy industry. Here we have applied a high-throughput isobaric labeling technique to measure oligosaccharide abundances in milk collected from Danish Holstein-Friesian and Jersey dairy cattle by liquid chromatography-mass spectrometry. With a total of 634 milk samples, this collection represents the largest sample set used for milk oligosaccharide profiling in the current literature. This study is also the first to use isobaric labeling for the purpose of measuring free oligosaccharides in a real sample set. We have identified 13 oligosaccharides that vary significantly by breed, with most structures being more abundant in the milk of Jersey cattle. The abundances of several oligosaccharides were increased in second-parity cows, and correlations between the abundances of oligosaccharide pairs were identified, potentially indicating similarities in their synthetic pathways. Fucosylated oligosaccharide structures were widely identified among both breeds. Improving our understanding of oligosaccharide production will aid in developing strategies to recover these compounds from processing streams and may enable their use as a functional ingredient in foods for infants and adults
Amplification of obliquity forcing through mean-annual and seasonal atmospheric feedbacks
International audiencePleistocene benthic ?18O records exhibit strong spectral power at ~41 kyr, indicating that global ice volume has been modulated by Earth's axial tilt. This feature, and weak spectral power in the precessional band, has been attributed to the influence of obliquity on mean-annual and seasonal insolation gradients at high latitudes. In this study, we use a coupled ocean-atmosphere general circulation model to quantify changes in continental snowfall associated with mean-annual and seasonal insolation forcing due to a change in obliquity. Our model results indicate that insolation changes associated with a decrease in obliquity amplify continental snowfall in two ways: (1) An increase in high-latitude winter insolation is enhanced through a low-cloud feedback, resulting in colder air temperatures and increased snow precipitation. (2) An increase in the summer insolation gradient enhances summer eddy activity, increasing vapor transport to high-latitude regions. In our experiments, a decrease in obliquity leads to an annual snowfall increase of 25.0 cm; just over one-half of this response (14.1 cm) is attributed to seasonal changes in insolation. Our results indicate that the role of insolation gradients is important in amplifying the relatively weak insolation forcing due to a change in obliquity. Nonetheless, the total snowfall response to obliquity is similar to that due to a shift in Earth's precession, suggesting that obliquity forcing alone can not account for the spectral characteristics of the ice-volume record
Pyramidal Atoms: Berylliumlike Hollow States
Based on the idea that four excited electrons arrange themselves around the
nucleus in the corners of a pyramid in order to minimize their mutual
repulsion, we present an analytical model of quadruply excited states. The
model shows excellent comparison with ab initio results and provides a clear
physical picture of the intrinsic motion of the four electrons. The model is
used to predict configuration-mixing fractions and spectra of these highly
correlated states.Comment: 4 pages, 2 figure
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