Discrete event simulation tool for analysis of qualitative models of continuous processing systems

An artificial intelligence design and qualitative modeling tool is disclosed for creating computer models and simulating continuous activities, functions, and/or behavior using developed discrete event techniques. Conveniently, the tool is organized in four modules: library design module, model construction module, simulation module, and experimentation and analysis. The library design module supports the building of library knowledge including component classes and elements pertinent to a particular domain of continuous activities, functions, and behavior being modeled. The continuous behavior is defined discretely with respect to invocation statements, effect statements, and time delays. The functionality of the components is defined in terms of variable cluster instances, independent processes, and modes, further defined in terms of mode transition processes and mode dependent processes. Model construction utilizes the hierarchy of libraries and connects them with appropriate relations. The simulation executes a specialized initialization routine and executes events in a manner that includes selective inherency of characteristics through a time and event schema until the event queue in the simulator is emptied. The experimentation and analysis module supports analysis through the generation of appropriate log files and graphics developments and includes the ability of log file comparisons

Autoguidance video sensor for docking

The Automated Rendezvous and Docking system (ARAD) is composed of two parts. The first part is the sensor which consists of a video camera ringed with two wavelengths of laser diode. The second part is a standard Remote Manipulator System (RMS) target used on the Orbiter that has been modified with three circular pieces of retro-reflective tape covered by optical filters which correspond to one of the wavelengths of laser diode. The sensor is on the chase vehicle and the target is on the target vehicle. The ARAD system works by pulsing one wavelength laser diodes and taking a picture. Then the second wavelength laser diodes are pulsed and a second picture is taken. One picture is subtracted from the other and the resultant picture is thresholded. All adjacent pixels above threshold are blobbed together (X and Y centroids calculated). All blob centroids are checked to recognize the target out of noise. Then the three target spots are windowed and tracked. The three target spot centroids are used to evaluate the roll, yaw, pitch, range, azimuth, and elevation. From that a guidance routine can guide the chase vehicle to dock with the target vehicle with the correct orientation

The Next Generation Advanced Video Guidance Sensor: Flight Heritage and Current Development

The Next Generation Advanced Video Guidance Sensor (NGAVGS) is the latest in a line of sensors that have flown four times in the last 10 years. The NGAVGS has been under development for the last two years as a long-range proximity operations and docking sensor for use in an Automated Rendezvous and Docking (AR&D) system. The first autonomous rendezvous and docking in the history of the U.S. Space Program was successfully accomplished by Orbital Express, using the Advanced Video Guidance Sensor (AVGS) as the primary docking sensor. That flight proved that the United States now has a mature and flight proven sensor technology for supporting Crew Exploration Vehicles (CEV) and Commercial Orbital Transport Systems (COTS) Automated Rendezvous and Docking (AR&D). NASA video sensors have worked well in the past: the AVGS used on the Demonstration of Autonomous Rendezvous Technology (DART) mission operated successfully in "spot mode" out to 2 km, and the first generation rendezvous and docking sensor, the Video Guidance Sensor (VGS), was developed and successfully flown on Space Shuttle flights in 1997 and 1998. This paper presents the flight heritage and results of the sensor technology, some hardware trades for the current sensor, and discusses the needs of future vehicles that may rendezvous and dock with the International Space Station (ISS) and other Constellation vehicles. It also discusses approaches for upgrading AVGS to address parts obsolescence, and concepts for minimizing the sensor footprint, weight, and power requirements. In addition, the testing of the various NGAVGS development units will be discussed along with the use of the NGAVGS as a proximity operations and docking sensor

Next Generation Advanced Video Guidance Sensor Development and Test

The Advanced Video Guidance Sensor (AVGS) was the primary docking sensor for the Orbital Express mission. The sensor performed extremely well during the mission, and the technology has been proven on orbit in other flights too. Parts obsolescence issues prevented the construction of more AVGS units, so the next generation of sensor was designed with current parts and updated to support future programs. The Next Generation Advanced Video Guidance Sensor (NGAVGS) has been tested as a breadboard, two different brassboard units, and a prototype. The testing revealed further improvements that could be made and demonstrated capability beyond that ever demonstrated by the sensor on orbit. This paper presents some of the sensor history, parts obsolescence issues, radiation concerns, and software improvements to the NGAVGS. In addition, some of the testing and test results are presented. The NGAVGS has shown that it will meet the general requirements for any space proximity operations or docking need

DART AVGS Performance

The Advanced Video Guidance Sensor (AVGS) was designed to be the proximity operations sensor for the Demonstration of Autonomous Rendezvous Technologies (DART). The DART mission flew in April of2005 and was a partial success. The AVGS did not get the opportunity to operate in every mode in orbit, but those modes in which it did operate were completely successful. This paper will detail the development, testing, and on-orbit performance of the AVGS

Design and fabrication of an autonomous rendezvous and docking sensor using off-the-shelf hardware

NASA Marshall Space Flight Center (MSFC) has developed and tested an engineering model of an automated rendezvous and docking sensor system composed of a video camera ringed with laser diodes at two wavelengths and a standard remote manipulator system target that has been modified with retro-reflective tape and 830 and 780 mm optical filters. TRW has provided additional engineering analysis, design, and manufacturing support, resulting in a robust, low cost, automated rendezvous and docking sensor design. We have addressed the issue of space qualification using off-the-shelf hardware components. We have also addressed the performance problems of increased signal to noise ratio, increased range, increased frame rate, graceful degradation through component redundancy, and improved range calibration. Next year, we will build a breadboard of this sensor. The phenomenology of the background scene of a target vehicle as viewed against earth and space backgrounds under various lighting conditions will be simulated using the TRW Dynamic Scene Generator Facility (DSGF). Solar illumination angles of the target vehicle and candidate docking target ranging from eclipse to full sun will be explored. The sensor will be transportable for testing at the MSFC Flight Robotics Laboratory (EB24) using the Dynamic Overhead Telerobotic Simulator (DOTS)

The Momentum Distribution of Liquid 3^3He

We present high-resolution neutron Compton scattering measurements of liquid $^3$He below its renormalized Fermi temperature. Theoretical predictions are in excellent agreement with the experimental data when instrumental resolution and final state effects are accounted for. Our results resolve the long-standing inconsistency between theoretical and experimental estimates of the average atomic kinetic energy.Comment: 5 pages, 4 figure

CLONAL CHARACTER OF F1 HYBRID LYMPHOCYTE SUBSET RECOGNITION OF PARENTAL CELLS IN ONE-WAY MIXED LYMPHOCYTE CULTURES

Proliferation of F1 hybrid lymphocytes in mixed lymphocyte cultures is stimulated by mitomycin-blocked parental cells. The demonstration of this phenomenon using F1 hybrids derived from congenic lines of mice establishes that the stimulation is controlled by genes in or closely linked to the major histocompatibility locus chromosome region. In agreement with the finding that tumor-bearing mice have an increased capacity for primary alloantigen recognition, it was observed that the F1 hybrid response to parent was also augmented by tumor bearing. Chromosomal analysis of dividing cells in one-way mixed cultures confirms that F1 cells, and not the blocked parental cells, enter mitosis. Stimulation of F1 cells by a soluble mediator liberated by the parental cells was not observed and mitomycin blocking of parental cells seems to be a completely effective blocking agent ensuring that parental cells can not enter DNA synthesis. The specificity and clonal nature of F1 recognition of parent was demonstrated using a 5-bromodeoxyuridine-suicide procedure. Distinct clones of lymphocytes in F1 spleen cell populations seem to recognize one or the other parent, but not both, in such experiments. These observations and others in tumor systems suggest that most or all heterozygous organisms may possess potentially self-reactive clones of lymphocytes

Cell adhesion and urothelial bladder cancer:the role of cadherin switching and related phenomena

Cadherins are mediators of cell–cell adhesion in epithelial tissues. E-cadherin is a known tumour suppressor and plays a central role in suppressing the invasive phenotype of cancer cells. However, the abnormal expression of N- and P-cadherin (‘cadherin switching’, CS) has been shown to promote a more invasive and m̀alignant phenotype of cancer, with P-cadherin possibly acting as a key mediator of invasion and metastasis in bladder cancer. Cadherins are also implicated in numerous signalling events related to embryonic development, tissue morphogenesis and homeostasis. It is these wide ranging effects and the serious implications of CS that make the cadherin cell adhesion molecules and their related pathways strong candidate targets for the inhibition of cancer progression, including bladder cancer. This review focuses on CS in the context of bladder cancer and in particular the switch to P-cadherin expression, and discusses other related molecules and phenomena, including EpCAM and the development of the cancer stem cell phenotype

Differential Effects of Word-Repetition Rate on Cognitive Defusion of Believability and Discomfort of Negative Self-Referential Thoughts Postintervention and at One-Month Follow-Up

Objective: The word repetition technique is used in acceptance and commitment therapy as a method of facilitating cognitive defusion from distressing thoughts. The present study conducted a randomised trial to manipulate the rate of word repetition and evaluate its impact on the efficacy of cognitive defusion. Method: Thirty-two participants repeated a self-chosen negative self-evaluative word for 30 seconds at the rates of one word per 0.5-, 1-, or 2-seconds. Visual analogue scales were used to measure the associated levels of believability and discomfort at pre- and immediately postrepetition, and 1 month later. Results: Both believability and discomfort were significantly reduced immediately after word repetition in the 0.5-seconds and 1-second conditions. There was a significantly greater reduction in Discomfort in the 1-second condition in comparison to the 2-second condition. The 1-second condition alone maintained significant reductions in both believability and discomfort at 1-month follow up. Conclusion: Differences in the cognitive defusion of distressing thoughts appear to be influenced by word repetition rate with repetition rates of one word per 0.5 and 1 seconds somewhat more effective for treating distressing private experiences associated with problem words