27 research outputs found
AVALIAÇÃO DO CURRÍCULO DE ENFERMAGEM: TRAVESSIA EM DIREÇÃO AO PROJETO PEDAGÓGICO
RESUMO O objetivo é descrever o processo de avaliação curricular implementado em 2009, na Escola de Enfermagem da UFMG. Para isso, foi adotado o Modelo de Avaliação Contexto, Insumos, Processo e Produto. O texto consta de quatro partes: construção coletiva da proposta curricular; concepção da avaliação curricular; dimensões do processo de avaliação; resultados obtidos em uma das estratégias empregadas. O processo de avaliação tem favorecido a análise coletiva sobre as dimensões do currículo, mesmo com participação docente aquém do esperado, a análise sobre os impactos da formação no mercado de trabalho e a inserção dos discentes no processo. O modelo adotado, embora de caráter racional, tem possibilitado reinvenções nos processos de avaliação, com implicações nos modos de subjetivação docente
Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults
Necator americanus Glutathione-S-Transferase-1 (Na-GST-1) plays a role in the digestion of host hemoglobin by adult N. americanus hookworms. Vaccination of laboratory animals with recombinant Na-GST-1 is associated with significant protection from challenge infection. Recombinant Na-GST-1 was expressed in Pichia pastoris and adsorbed to aluminum hydroxide adjuvant (Alhydrogel) according to current Good Manufacturing Practice. Two Phase 1 trials were conducted in 142 healthy adult volunteers in the United States and Brazil, first in hookworm-naïve individuals and then in residents of a N. americanus endemic area in Brazil. Volunteers received one of three doses of recombinant Na-GST-1 (10, 30, or 100 μg) adjuvanted with Alhydrogel, adjuvanted with Alhydrogel and co-administered with an aqueous formulation of Glucopyranosyl Lipid A (GLA-AF), or the hepatitis B vaccine. Vaccinations were administered via intramuscular injection on days 0, 56, and 112. Na-GST-1/Alhydrogel was well tolerated in both hookworm-naïve and hookworm-exposed adults, with the most common adverse events being mild to moderate injection site pain and tenderness, and mild headache and nausea; no vaccine-related severe or serious adverse events were observed. Antigen-specific IgG antibodies were induced in a dose-dependent fashion, with increasing levels observed after each vaccination in both trials. The addition of GLA-AF to Na-GST-1/Alhydrogel did not result in significant increases in specific IgG responses. In both the US and Brazil studies, the predominant IgG subclass induced against Na-GST-1 was IgG1, with lesser amounts of IgG3. Vaccination of both hookworm-naïve and hookworm-exposed adults with recombinant Na-GST-1 was safe, well tolerated, and resulted in significant antigen-specific IgG responses. Based on these results, this vaccine will be advanced into clinical trials in children and eventual efficacy studies.Fil: Diemert, David J.. The George Washington University; Estados UnidosFil: Freire, Janaína. Fundación Oswaldo Cruz; BrasilFil: Vanderson, Valente. Fundación Oswaldo Cruz; BrasilFil: Talles, Federico. Fundación Oswaldo Cruz; BrasilFil: Grahek, Shannon. The George Washington University; Estados UnidosFil: Campbell, Doreen. The George Washington University; Estados UnidosFil: Jariwala, Amar. The George Washington University; Estados UnidosFil: Periago, Maria Victoria. Fundación Oswaldo Cruz; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Enk, Martin. Fundación Oswaldo Cruz; BrasilFil: Gazzinelli, María Flavia. Universidade Federal do Minas Gerais; BrasilFil: Bottazzi, María Elena. Baylor College of Medicine; Estados UnidosFil: Hamilton, Roberto. University Johns Hopkins; Estados UnidosFil: Brelsford, Jill. The George Washington University; Estados UnidosFil: Yakovleva, Anna. The George Washington University; Estados UnidosFil: Guangzhao, Li. The George Washington University; Estados UnidosFil: Peng, Jin. The George Washington University; Estados UnidosFil: Correa Oliveira, Rodrigo. Fundación Oswaldo Cruz; BrasilFil: Hotez, Peter. Baylor College of Medicine; Estados UnidosFil: Bethony, Jeffrey. The George Washington University; Estados Unido
Development of cognitive abilities of children infected with helminths through health education
Impact of gender on the decision to participate in a clinical trial: a cross-sectional study
Development of cognitive abilities of children infected with helminths through health education
INTRODUCTION: The aim of this study was to evaluate the effect of health education in learning and cognitive development of children infected, previously treated in an endemic area for helminthiasis. METHODS: It is a longitudinal, experimental, with random allocation of participants. The study included 87 children of both sexes enrolled in the school hall of Maranhão, State of Minas Gerais, Brazil, and divided into two groups: intervention and control. Initially the children were submitted to the parasitological fecal examination for infection diagnosis and, when positive, they were treated. For the data collection, a structured questionnaire and the psychological tests Raven, Wisc-III and DAP III were applied, before and after the educational intervention. For the group comparison, the Mann Whitney test was used, and established significance level of 5%. RESULTS: It was found that previously infected children who received the educational intervention, children showed higher performance than the control group in strutured questionnaire (p<0.05). CONCLUSIONS: It is acceptable to suppose the positive influence and the importance in the use of educational interventions in the cognitive recovery and learning of children previously treated with anthelmintics
Estratégias de ensino utilizadas na formação do enfermeiro-educador: revisão integrativa
Objective: to investigate which teaching strategies are used in the training of the nurse-educator in nursing undergraduate courses at a national and international level. Methods: an integrative review carried out in the databases Latin American and Caribbean Health Sciences Literature, Current Index to Nursing and Allied Health Literature, National Center for Biotechnology Information, Web of Science, SCOPUS. No time limits were determined. Results: Based on the seven selected articles, different teaching strategies used in the training of nurse-educators in Nursing courses were identified in countries such as Brazil, United States of America, United Kingdom, Spain and Germany. The strategies identified were: Digital Teaching Materials, Role Playing Game, Problematization, Poetry, Practical Experience, Educational Games and Educational Action Formulation and Development. Conclusion: the strategies identified relate to the Modern-Traditional and Modern-Dialogical benchmarks, with little or no openness to sensitive, ethical-aesthetic-political experimentation in the fields of action that relate to Health Education.Objetivo: investigar as estratégias de ensino utilizadas na formação do enfermeiro-educador nos cursos de graduação em enfermagem em âmbito nacional e internacional. Métodos: revisão integrativa realizada nas bases Literatura Latino-Americana e do Caribe em Ciências da Saúde, Current Index to Nursing and Allied Health Literature, National Center for Biotechnology Information, Web of Science, SCOPUS. Não foram determinados os limites temporais. Resultados: com base nos sete artigos selecionados, identificaram-se diferentes estratégias de ensino utilizadas na formação de enfermeiros-educadores nos cursos de Enfermagem em países como o Brasil, Estados Unidos da América, Reino Unido, Espanha e Alemanha. As estratégias identificadas foram: Materiais Didáticos Digitais, Role Playing Game, Problematização, Poesia, Experiência Prática, Jogos Educativos e Formulação e Desenvolvimento de Ação Educativa. Conclusão: as estratégias identificadas relacionam-se com os referenciais Moderno-Tradicional e Moderno-Dialógico, com pouca ou nenhuma abertura à experimentação sensível, ética-estética-política nos campos de ação que se relacionam com a Educação em Saúde
A history of hookworm vaccine development
The human hookworms Necator americanus and Ancylostoma duodenale remain among the most common infections of humans in areas of rural poverty in the developing regions of the world, with an estimated 1 billion people infected with one or more of these parasites. Herein, we review the nearly 100 y of research, development, animal testing and fieldwork that haveled to our current progress in recombinant hookworm vaccines. We begin with the identification of hookworm at the start ofthe 20th century in Southern US, then discuss the progress in developed countries to eliminate human hookworm infection,and then the industrial development and field use in the 1970s a canine hookworm vaccine (Ancylostoma caninum), and finally our progress to date in the development and clinical testing of an array of recombinant antigens to prevent human hookworm disease from N. americanus infection. Special attention is given to the challenges faced in the development of a vaccine against a blood-feeding nematode, including the epidemiology of infection (high prevalence of infection), pathogenesis (chronic infection that increases with the age of the host), and a robust immune response that fails to confer the protection in thehost and a concomitant absence of correlates of protection by a successful vaccine could be developed and tested. Finally, we provide the optimal and acceptable profiles of a human hookworm vaccine, including the proposed indication, target population and route of administration, as developed by the Human Hookworm Vaccine Initiative, the only group currently working on vaccines targeting this parasite. © 2011 Landes Bioscience
Metodologías innovadoras para la enseñanza de la seguridad del paciente en el pregrado de Enfermería: scoping review
14 paginasObjetivo: identificar las metodologías innovadoras utilizadas para la enseñanza de la seguridad del paciente en el pregrado de Enfermería.
Materiales y método: scoping review realizada de acuerdo con las recomendaciones del Joanna Briggs Institute Reviewers’ Manual, por medio de las bases de datos: Medline/PubMed, Cumulative Index of Nursing and Allied Health, Scopus, Web of Science, Education Resources Information Center, Literatura Latinoamericana y del Caribe en Ciencias de la Salud, Catálogo de Tesis de la Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, The National Library of Australia’s, Academic Archive Online, Digital Access to Research Theses Europe E-Theses Portal, Electronic Theses Online Service, Repositório Científico de Acesso Aberto de Portugal, National ETD Portal y Theses Canada.
Resultados: se incluyeron 19 estudios; la mayoría de tipo descriptivo (n = 8; 42,1 %) y casi experimental (n = 7; 36,8 %); con enfoque cuantitativo (n = 11; 57,9 %); realizados en los Estados Unidos (n = 4; 21,1 %), en el 2013 (n = 4; 21,1 %) y el 2017 (n = 4; 21,1 %). Las metodologías innovadoras utilizadas para la enseñanza de la seguridad del paciente en el pregrado de Enfermería que se destacaron fueron: el escenario de práctica asistencial simulada en laboratorio (n = 14; 73,7 %) y los videos educacionales (n = 7; 36,8 %).
Conclusiones: se identificó que las metodologías innovadoras utilizadas para la enseñanza de la seguridad del paciente en el pregrado de Enfermería fueron simulacro, videos, escenificación/dramatización y películas, todas aplicadas en la modalidad de enseñanza presencial
Innovative Methodologies to Teach Patient Safety in Undergraduate Nursing: Scoping Review
Metodologias inovadoras para o ensino da segurança do paciente na graduação em Enfermagem: scoping reviewMetodologías innovadoras para la enseñanza de la seguridad del paciente en el pregrado de Enfermería: scoping reviewObjective: This work sought to identify the innovative methodologies used to teach patient safety in undergraduate Nursing.Materials and method: this is a scoping review conducted according to the recommendations by the Joanna Briggs Institute Reviewers’ Manual, through the databases: Medline/PubMed, Cumulative Index of Nursing and Allied Health, Scopus, Web of Science, Education Resources Information Center, Latin American and Caribbean Literature on Health Sciences, Catálogo de Tesis de la Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, The National Library of Australia’s Academic Archive Online, Digital Access to Research Theses Europe E-Theses Portal, Electronic Theses Online Service, Repositório Científico de Acesso Aberto de Portugal, National ETD Portal, and Theses Canada.Results: the study included 19 studies, most of descriptive type (n = 8; 42.1 %) and quasi-experimental (n = 7; 36.8 %) with quantative approach (n = 11; 57.9 %), conducted in the United States (n = 4; 21.1 %), in 2013 (n = 4; 21.1 %) and 2017 (n = 4; 21.1 %). The innovative methodologies used to teach patient safety in undergraduate Nursing that were highlighted included the scenario of the care practice simulated in the laboratory (n = 14; 73.7 %) and educational videos (n = 7; 36.8 %).Conclusions: it was identified that innovative methodologies used to teach patient safety in undergraduate Nursing were simulation, videos, staging/role playing, and films, all applied in the classroom teaching modality.Para citar este artigo / Para citar este artículo / To reference this articleGomes ATL, Salvador PTCO, Goulart CF, Cecilio SG, Bethony MFG. Innovative Methodologies to Teach Patient Safety in Undergraduate Nursing: Scoping Review. Aquichan 2020;20(1):e2018. DOI: https://doi.org/10.5294/aqui.2020.20.1.8Recibido: 18/07/2019Aprobado: 06/12/2019Publicado: 13/03/2020Metodologias inovadoras para o ensino da segurança do paciente na graduação em Enfermagem: scoping reviewMetodologías innovadoras para la enseñanza de la seguridad del paciente en el pregrado de Enfermería: scoping reviewObjetivo: identificar las metodologías innovadoras utilizadas para la enseñanza de la seguridad del paciente en el pregrado de Enfermería.Materiales y método: scoping review realizada de acuerdo con las recomendaciones del Joanna Briggs Institute Reviewers’ Manual, por medio de las bases de datos: Medline/PubMed, Cumulative Index of Nursing and Allied Health, Scopus, Web of Science, Education Resources Information Center, Literatura Latinoamericana y del Caribe en Ciencias de la Salud, Catálogo de Tesis de la Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, The National Library of Australia’s, Academic Archive Online, Digital Access to Research Theses Europe E-Theses Portal, Electronic Theses Online Service, Repositório Científico de Acesso Aberto de Portugal, National ETD Portal y Theses Canada.Resultados: se incluyeron 19 estudios; la mayoría de tipo descriptivo (n = 8; 42,1 %) y casi experimental (n = 7; 36,8 %); con enfoque cuantitativo (n = 11; 57,9 %); realizados en los Estados Unidos (n = 4; 21,1 %), en el 2013 (n = 4; 21,1 %) y el 2017 (n = 4; 21,1 %). Las metodologías innovadoras utilizadas para la enseñanza de la seguridad del paciente en el pregrado de Enfermería que se destacaron fueron: el escenario de práctica asistencial simulada en laboratorio (n = 14; 73,7 %) y los videos educacionales (n = 7; 36,8 %).Conclusiones: se identificó que las metodologías innovadoras utilizadas para la enseñanza de la seguridad del paciente en el pregrado de Enfermería fueron simulacro, videos, escenificación/dramatización y películas, todas aplicadas en la modalidad de enseñanza presencial.Para citar este artigo / Para citar este artículo / To reference this articleGomes ATL, Salvador PTCO, Goulart CF, Cecilio SG, Bethony MFG. Innovative Methodologies to Teach Patient Safety in Undergraduate Nursing: Scoping Review. Aquichan 2020;20(1):e2018. DOI: https://doi.org/10.5294/aqui.2020.20.1.8Recibido: 18/07/2019Aprobado: 06/12/2019Publicado: 13/03/2020Metodologias inovadoras para o ensino da segurança do paciente na graduação em Enfermagem: scoping reviewMetodologías innovadoras para la enseñanza de la seguridad del paciente en el pregrado de Enfermería: scoping reviewObjetivo: identificar as metodologias inovadoras utilizadas para o ensino da segurança do paciente na graduação em Enfermagem.Materiais e método: scoping review conduzida conforme as recomendações do Joanna Briggs Institute Reviewers’ Manual, por meio das bases de dados: Medline/PubMed, Cumulative Index of Nursing and Allied Health, Scopus, Web of Science, Education Resources Information Center, Literatura Latino-Americana e do Caribe em Ciências da Saúde, Catálogo de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, The National Library of Australia’s, Academic Archive Online, Digital Access to Research Theses Europe E-Theses Portal, Electronic Theses Online Service, Repositório Científico de Acesso Aberto de Portugal, National ETD Portal e Theses Canada.Resultados: foram incluídos 19 estudos; a maioria do tipo descritivo (n = 8; 42,1 %) e quase experimental (n = 7; 36,8 %); com abordagem quantitativa (n = 11; 57,9 %); realizados nos Estados Unidos (n = 4; 21,1 %), em 2013 (n = 4; 21,1 %) e em 2017 (n = 4; 21,1 %). As metodologias inovadoras utilizadas para o ensino da segurança do paciente na graduação em Enfermagem que se destacaram foram o cenário de prática assistencial simulada em laboratório (n = 14; 73,7 %) e os vídeos educacionais (n = 7; 36,8 %).Conclusões: identificou-se que as metodologias inovadoras utilizadas para o ensino da segurança do paciente na graduação em Enfermagem foram simulação, vídeos, encenação/dramatização e filmes, todas aplicadas na modalidade de ensino presencial.Para citar este artigo / Para citar este artículo / To reference this articleGomes ATL, Salvador PTCO, Goulart CF, Cecilio SG, Bethony MFG. Innovative Methodologies to Teach Patient Safety in Undergraduate Nursing: Scoping Review. Aquichan 2020;20(1):e2018. DOI: https://doi.org/10.5294/aqui.2020.20.1.8Recibido: 18/07/2019Aprobado: 06/12/2019Publicado: 13/03/202