13 research outputs found
Book Review: Psychiatric Justice
In an era in which extensive judicial emphasis has been placed on due process of law in criminal proceedings, both in the federal courts and in the state courts, Dr. Szasz\u27s book serves as a jarring reminder that in at least one vital area of the concept of due process, much remains to be done. The emerging definition of due process has enunciated the rights guaranteed the individual by the Fourth, Fifth, Sixth, and Fourteenth Amendments; and viewed within that framework, this book, although published in 1965, remains particularly timely, for Szasz, speaking as a psychiatrist, endeavors to demonstrate how the criminal procedure in virtually every jurisdiction in the United States operates to use psychiatry as a weapon against the individual. This injustice is accomplished through the application of two procedures: the involuntary pretrial psychiatric examination of the accused to determine his fitness to stand trial and the coerced plea of not guilty by reason of insanity induced when the accused is found fit to stand trial. Either of these procedures, the author maintains, effectively denies the accused his Sixth Amendment right to trial
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MyeloidâLymphoid Ontogeny in the Rhesus Monkey (Macaca mulatta)
Establishment of a functional immune system has important implications for health and disease, yet questions remain regarding the mechanism, location, and timing of development of myeloid and lymphoid cell compartments. The goal of this study was to characterize the ontogeny of the myeloid-lymphoid system in rhesus monkeys to enhance current knowledge of the developmental sequence of B-cell (CD20, CD79), T-cell (CD3, CD4, CD8, FoxP3), dendritic cell (CD205), and macrophage (CD68) lineages in the fetus and infant. Immunohistochemical assessments addressed the temporal and spatial expression of select phenotypic markers in the developing liver, thymus, spleen, lymph nodes, gut-associated lymphoid tissue (GALT), and bone marrow with antibodies known to cross-react with rhesus cells. CD3 was the earliest lymphoid marker identified in the first trimester thymus and, to a lesser extent, in the spleen. T-cell markers were also expressed midgestation on cells of the liver, spleen, thymus, and in Peyer's patches of the small and large intestine, and where CCR5 expression was noted. A myeloid marker, CD68, was found on hepatic cells near blood islands in the late first trimester. B-cell markers were observed mid-second trimester in the liver, spleen, thymus, lymph nodes, bone marrow spaces, and occasionally in GALT. By the late third trimester and postnatally, secondary follicles with germinal centers were present in the thymus, spleen, and lymph nodes. These results suggest that immune ontogeny in monkeys is similar in temporal and anatomical sequence when compared to humans, providing important insights for translational studies
Natural Scaffolds for Renal Differentiation of Human Embryonic Stem Cells for Kidney Tissue Engineering
Dose Response of Listeria monocytogenes Invasion, Fetal Morbidity, and Fetal Mortality after Oral Challenge in Pregnant and Nonpregnant Mongolian Gerbils
Brief of \u3ci\u3eAmici Curiae\u3c/i\u3e Law Professors and Economists in Support of Petitioner in \u3ci\u3eSouth Dakota v. Wayfair, Inc., et al.\u3c/i\u3e
Amici are professors of tax law and economics at universities across the United States. As scholars and teachers, they have considered the economic consequences of this Courtâs decision in Quill Corp. v. North Dakota, 504 U.S. 298 (1992), and have concluded that Quillâs dormant Commerce Clause holding should be overruled. Amici join this brief solely on their own behalf and not as representatives of their universities. A full list of amici appears in Appendix A