Main ways of improving the efficiency of fuel and energy resources utilization in energy production

The paper analyzes the main ways of improving the energy efficiency of boiler plants that provide thermal energy to industrial enterprises and housing and utilities sectors. The paper also presents the methodology for evaluating the effectiveness of energy-saving measures. The authors point out the main measures to save boiler and furnace fuel, heat and electric energy

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology

Due to its poor capacity for regeneration, the heart is particularly sensitive to the loss of contractile cardiomyocytes. The onslaught of damage caused by ischaemia and reperfusion, occurring during an acute myocardial infarction and the subsequent reperfusion therapy, can wipe out upwards of a billion cardiomyocytes. A similar program of cell death can cause the irreversible loss of neurons in ischaemic stroke. Similar pathways of lethal cell injury can contribute to other pathologies such as left ventricular dysfunction and heart failure caused by cancer therapy. Consequently, strategies designed to protect the heart from lethal cell injury have the potential to be applicable across all three pathologies. The investigators meeting at the 10th Hatter Cardiovascular Institute workshop examined the parallels between ST-segment elevation myocardial infarction (STEMI), ischaemic stroke, and other pathologies that cause the loss of cardiomyocytes including cancer therapeutic cardiotoxicity. They examined the prospects for protection by remote ischaemic conditioning (RIC) in each scenario, and evaluated impasses and novel opportunities for cellular protection, with the future landscape for RIC in the clinical setting to be determined by the outcome of the large ERIC-PPCI/CONDI2 study. It was agreed that the way forward must include measures to improve experimental methodologies, such that they better reflect the clinical scenario and to judiciously select combinations of therapies targeting specific pathways of cellular death and injury

Ischaemic conditioning and reperfusion injury

The 30-year anniversary of the discovery of 'ischaemic preconditioning' is in 2016. This endogenous phenomenon can paradoxically protect the heart from acute myocardial infarction by subjecting it to one or more brief cycles of ischaemia and reperfusion. Apart from complete reperfusion, this method is the most powerful intervention known for reducing infarct size. The concept of ischaemic preconditioning has evolved into 'ischaemic conditioning', a term that encompasses a number of related endogenous cardioprotective strategies, applied either directly to the heart (ischaemic preconditioning or postconditioning) or from afar, for example a limb (remote ischaemic preconditioning, perconditioning, or postconditioning). Investigations of signalling pathways underlying ischaemic conditioning have identified a number of therapeutic targets for pharmacological manipulation. Over the past 3 decades, a number of ischaemic and pharmacological cardioprotection strategies, discovered in experimental studies, have been examined in the clinical setting of acute myocardial infarction and CABG surgery. The results from many of the studies have been disappointing, and no effective cardioprotective therapy is currently used in clinical practice. Several large, multicentre, randomized, controlled clinical trials on cardioprotection have highlighted the challenges of translating ischaemic conditioning and pharmacological cardioprotection strategies into patient benefit. However, a number of cardioprotective therapies have shown promising results in reducing infarct size and improving clinical outcomes in patients with ischaemic heart disease

Technology of creation of composite materials for manufacturing high-loaded equipment and tool

The article presents the results of studying of composite materials on boron basis on carbon steels from developed powder environment with application of various activators of treatment process and coverings properties analysis - hardness, microhardness, tendency to spelling, wear resistances in conditions of hydroabrasive wear and sliding friction

Technology of creation of composite materials for manufacturing high-loaded equipment and tool

The article presents the results of studying of composite materials on boron basis on carbon steels from developed powder environment with application of various activators of treatment process and coverings properties analysis - hardness, microhardness, tendency to spelling, wear resistances in conditions of hydroabrasive wear and sliding friction

Main ways of improving the efficiency of fuel and energy resources utilization in energy production

The paper analyzes the main ways of improving the energy efficiency of boiler plants that provide thermal energy to industrial enterprises and housing and utilities sectors. The paper also presents the methodology for evaluating the effectiveness of energy-saving measures. The authors point out the main measures to save boiler and furnace fuel, heat and electric energy

Пути сокращения засоления и восстановления почв в районах производственной деятельности ОАО «Беларуськалий»

The article is a review of the prominent technical solutions regarding potash salt deposits mining. The article shows the efficiency of application of biological restoration of saline soil by using salt marsh plants

Пути сокращения засоления и восстановления почв в районах производственной деятельности ОАО «Беларуськалий»

The article is a review of the prominent technical solutions regarding potash salt deposits mining. The article shows the efficiency of application of biological restoration of saline soil by using salt marsh plants