Three-Dimensional Mathematical Modeling of Dynamics Interfaces Between Aluminum, Electrolytes and Reverse Zone of Oxidized Metal Depending on the Potencial Distribution

В статье представлена новая математическая модель с высокой степенью детализации описания изучаемых процессов. Проведены расчёты электролизёра Содерберга для модельной задачи, а также расчёты для многоанодного электролизёра. Для описания гидродинамики процесса электролиза используется система уравнений Навье-Стокса. Распределение электромагнитных полей описывается системой уравнений Максвелла. Рассматривается влияние распределения потенциала по аноду на МГД-стабильность электролиза, а также даётся сравнительный анализ численных экспериментовThe mathematical model with a high detailed description of the studied processes is presented in current paper. Results of modeling Soderbergh’s reduction cell for model task and for reduction cell with multiple anodes are also presented. System of the equations of Navier-Stokes is used for modeling of hydrodynamics of process of electrolysis. Distribution of electromagnetic fields is fitted to Maxwell’s system of equations. Influence of distribution of electric potential over the anode on MHD-stability of process is considered and comparative analysis of numerical experiments is also give

Inter-calibration of Infrared Channels of Geostationary Meteorological Satellite Imagers

This article examines a method of inter-calibration for MSU-GS imager of the Russian Geostationary Earth Orbit (GEO) satellite Elektro-L No. 2. Since the launch (December 11, 2015), the satellite's radiation cooler has been operating in an abnormal mode, so the calibration of the IR channels of the MSU-GS imager differed from that pre-flight and, in general, could have a daily variability. To ensure the satellite's further operation in orbit, it was necessary to calibrate imager channels at a frequency that would allow to identify daily calibration course to detect and compensate its sources. In order to do this, we have developed a special method of GEO-GEO inter-calibration. The calibration of MSU-GS was performed using SEVIRI imager installed on the GEO satellite Meteosat-10. SEVIRI was chosen as a reference instrument because its spectral channels are similar to those of MSU-GS. The MSU-GS was calibrated according to the regressions calculated from the simultaneous images of the field of regard selected between the sub-satellite points. The dynamic brightness temperature range was determined by deep convective clouds in high troposphere and warm ocean surface. Using the proposed method of inter-calibration, it was possible to confirm the absence of a significant daily variation of the calibration since November 2017. The amplitude of the variation smoothly increases from ~0.2 K at high (~300 K) BTs to ~1.0 K when the brightness temperature decreased to 200 K. These estimates allow the use of the Fourier spectrometer IKFS-2 installed on the Russian Low-Earth-Orbit (LEO) satellite Meteor-M No. 2 to verify the developed GEO-GEO scheme of inter-calibration. Despite the specifics of the situation on board Elektro-L No. 2, the proposed method of GEO-GEO inter-calibration can be applied to radiometers of other neighboring satellites that differ in SSP and spatial resolution

Molecular alliance of Lymantria dispar multiple nucleopolyhedrovirus and a short unmodified antisense oligonucleotide of its anti-apoptotic IAP-3 gene: A novel approach for gypsy moth control

Baculovirus IAP (inhibitor-of-apoptosis) genes originated by capture of host genes. Unmodified short antisense DNA oligonucleotides (oligoDNAs) from baculovirus IAP genes can down-regulate specific gene expression profiles in both baculovirus-free and baculovirus-infected insects. In this study, gypsy moth (Lymantria dispar) larvae infected with multiple nucleopolyhedrovirus (LdMNPV), and LdMNPV-free larvae, were treated with oligoDNA antisense to the RING (really interesting new gene) domain of the LdMNPV IAP-3 gene. The results with respect to insect mortality, biomass accumulation, histological studies, RT-PCR, and analysis of DNA apoptotic fragmentation suggest that oligoRING induced increased apoptotic processes in both LdMNPV-free and LdMNPV-infected insect cells, but were more pronounced in the latter. These data open up possibilities for promising new routes of insect pest control using antisense phosphodiester DNA oligonucleotides

Molecular Alliance of Lymantria dispar Multiple Nucleopolyhedrovirus and a Short Unmodified Antisense Oligonucleotide of Its Anti-Apoptotic IAP-3 Gene: A Novel Approach for Gypsy Moth Control

Baculovirus IAP (inhibitor-of-apoptosis) genes originated by capture of host genes. Unmodified short antisense DNA oligonucleotides (oligoDNAs) from baculovirus IAP genes can down-regulate specific gene expression profiles in both baculovirus-free and baculovirus-infected insects. In this study, gypsy moth (Lymantria dispar) larvae infected with multiple nucleopolyhedrovirus (LdMNPV), and LdMNPV-free larvae, were treated with oligoDNA antisense to the RING (really interesting new gene) domain of the LdMNPV IAP-3 gene. The results with respect to insect mortality, biomass accumulation, histological studies, RT-PCR, and analysis of DNA apoptotic fragmentation suggest that oligoRING induced increased apoptotic processes in both LdMNPV-free and LdMNPV-infected insect cells, but were more pronounced in the latter. These data open up possibilities for promising new routes of insect pest control using antisense phosphodiester DNA oligonucleotides

26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 - Meeting Abstracts - Antwerp, Belgium. 15–20 July 2017

This work was produced as part of the activities of FAPESP Research,\ud Disseminations and Innovation Center for Neuromathematics (grant\ud 2013/07699-0, S. Paulo Research Foundation). NLK is supported by a\ud FAPESP postdoctoral fellowship (grant 2016/03855-5). ACR is partially\ud supported by a CNPq fellowship (grant 306251/2014-0)

Topological Charge of Light Fields with a Polarization Singularity

We have studied diverse vector and hybrid light fields, including those with multiple polarization singularities, and have derived relationships for polarization singularity indices based on the familiar Berry formula, which is normally utilized to find the topological charge of a scalar vortex light field. The fields with pure polar-angle-dependent polarization in the beam cross-section are shown to feature either polarization singularity lines outgoing from the center or a single polarization singularity point at the beam center. The fields with pure radial-variable-dependent polarization are shown to have no polarization singularities and zero polarization index. The vector fields with both polar-angle- and radial-variable-dependent polarization are shown to have multiple polarization singularity points that are scattered across the cross-section. A vector field with higher-order radial polarization and a real parameter was also studied and was shown to feature either several polarization singularity lines outgoing from the center or a central singular point, depending on the parameter value. Notably, at different parameter values, the polarization singularity index of such a field can take half-integer, integer, or zero values

Chronology of critical events in neonatal rat ventricular myocytes occurring during reperfusion after simulated ischemia.

While an ischemic insult poses a lethal danger to myocardial cells, a significant proportion of cardiac myocytes remain viable throughout the ischemic episode and die, paradoxically, only after the blood flow is reinstated. Despite decades of research, the actual chronology of critical events leading to cardiomyocyte death during the reperfusion phase remains poorly understood. Arguably, identification of the pivotal event in this setting is necessary to design effective strategies aimed at salvaging the myocardium after an ischemic attack. Here we used neonatal rat ventricular myocytes (NRVMs) subjected to 20-30 min of simulated ischemia followed by 1 hour of "reperfusion". Using different combinations of spectrally-compatible fluorescent indicators, we analyzed the relative timing of the following events: (1) abnormal increase in cytoplasmic [Ca2+] (TCaCy); (2) abnormal increase in mitochondrial [Ca2+] (TCaMi); (3) loss of mitochondrial inner membrane potential (ΔΨm) indicating mitochondrial permeability transitions (TMPT); (4) sacrolemmal permeabilization (SP) to the normally impermeable small fluorophore TO-PRO3 (TSP). In additional experiments we also analyzed the timing of abnormal uptake of Zn2+ into the cytoplasm (TZnCy) relative to TCaCy and TSP. We focused on those NRVMs which survived anoxia, as evidenced by at least 50% recovery of ΔΨm and the absence of detectable SP. In these cells, we found a consistent sequence of critical events in the order, from first to last, of TCaCy, TCaMi, TMPT, TSP. After detecting TCaCy and TCaMi, abrupt switches between 1.1 mM and nominally zero [Ca2+] in the perfusate quickly propagated to the cytoplasmic and mitochondrial [Ca2+]. Depletion of the sarcoplasmic reticulum with ryanodine (5 μM)/thapsigargin (1 μM) accelerated all events without changing their order. In the presence of ZnCl2 (10-30 μM) in the perfusate we found a consistent timing sequence TCaCy < TZn ≤ TSP. In some cells ZnCl2 interfered with Ca2+ uptake, causing "steps" or "gaps" in the [Ca2+]Cy curve, a phenomenon never observed in the absence of ZnCl2. Together, these findings suggest an evolving permeabilization of NRVM's sarcolemma during reoxygenation, in which the expansion of the pore size determines the timing of critical events, including TMPT

Spin Hall Effect before and after the Focus of a High-Order Cylindrical Vector Beam

It is known that in the cross-section of a high-order cylindrical vector beam (CVB), polarization is locally linear. The higher the beam order, the higher the number of full rotations of the vector of local linear polarization when passing along a contour around the optical axis. It is also known that both in the input and in the focal planes, the CVB has neither the spin angular momentum (SAM), nor the orbital angular momentum (OAM). We demonstrate here that near the focal plane of the CVB (before and after the focus), an even number of local subwavelength areas is generated, where the polarization vector in each point is rotating. In addition, in the neighboring areas, polarization vectors are rotating in different directions, so that the longitudinal component of SAM vectors in these neighboring areas is of the opposite sign. In addition, after the beam passes the focus, the rotation direction of the polarization vector in each point of the beam cross-section is changed to the opposite one. Such spatial separation of the left and right rotation of the polarization vectors manifests so that the optical spin Hall effect takes place

Spin Hall Effect before and after the Focus of a High-Order Cylindrical Vector Beam

It is known that in the cross-section of a high-order cylindrical vector beam (CVB), polarization is locally linear. The higher the beam order, the higher the number of full rotations of the vector of local linear polarization when passing along a contour around the optical axis. It is also known that both in the input and in the focal planes, the CVB has neither the spin angular momentum (SAM), nor the orbital angular momentum (OAM). We demonstrate here that near the focal plane of the CVB (before and after the focus), an even number of local subwavelength areas is generated, where the polarization vector in each point is rotating. In addition, in the neighboring areas, polarization vectors are rotating in different directions, so that the longitudinal component of SAM vectors in these neighboring areas is of the opposite sign. In addition, after the beam passes the focus, the rotation direction of the polarization vector in each point of the beam cross-section is changed to the opposite one. Such spatial separation of the left and right rotation of the polarization vectors manifests so that the optical spin Hall effect takes place