2,919 research outputs found

    A Study of the Effects of Foreign Direct Investment on the Economy of the State of New Hampshire Since 1973

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    The purpose of the thesis is to determine the impact that foreign direct investment has had on New Hampshire. New Hampshire as a state was impacted far less severely than much of the rest of the country, which could be considered surprising given the relatively high cost of housing in the state. I believe that part of what made New Hampshire more recession resistant is having the right foreign companies providing employment. To do this, I will be looking at FDI as a percentage of GDP over the previous 40 years and looking for a correlation between a higher percentage and national recession. I will also look at specific foreign corporations that lend the most to the New Hampshire economy to obtain a more specific view of the impact such companies have on both their communities and the state as a whole. This data could prove useful to New Hampshire as well as other states looking to protect against recession, as well as corporations looking to justify FDI to various governments

    Mechanics of collective unfolding

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    Mechanically induced unfolding of passive crosslinkers is a fundamental biological phenomenon encountered across the scales from individual macro-molecules to cytoskeletal actin networks. In this paper we study a conceptual model of athermal load-induced unfolding and use a minimalistic setting allowing one to emphasize the role of long-range interactions while maintaining full analytical transparency. Our model can be viewed as a description of a parallel bundle of N bistable units confined between two shared rigid backbones that are loaded through a series spring. We show that the ground states in this model correspond to synchronized, single phase configurations where all individual units are either folded or unfolded. We then study the fine structure of the wiggly energy landscape along the reaction coordinate linking the two coherent states and describing the optimal mechanism of cooperative unfolding. Quite remarkably, our study shows the fundamental difference in the size and structure of the folding-unfolding energy barriers in the hard (fixed displacements) and soft (fixed forces) loading devices which persists in the continuum limit. We argue that both, the synchronization and the non-equivalence of the mechanical responses in hard and soft devices, have their origin in the dominance of long-range interactions. We then apply our minimal model to skeletal muscles where the power-stroke in acto-myosin crossbridges can be interpreted as passive folding. A quantitative analysis of the muscle model shows that the relative rigidity of myosin backbone provides the long-range interaction mechanism allowing the system to effectively synchronize the power-stroke in individual crossbridges even in the presence of thermal fluctuations. In view of the prototypical nature of the proposed model, our general conclusions pertain to a variety of other biological systems where elastic interactions are mediated by effective backbones

    Angular Momentum Evolution of Stars in the Orion Nebula Cluster

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    (Abridged) We present theoretical models of stellar angular momentum evolution from the Orion Nebula Cluster (ONC) to the Pleiades and the Hyades. We demonstrate that observations of the Pleiades and Hyades place tight constraints on the angular momentum loss rate from stellar winds. The observed periods, masses and ages of ONC stars in the range 0.2--0.5 M⊙_\odot, and the loss properties inferred from the Pleiades and Hyades stars, are then used to test the initial conditions for stellar evolution models. We use these models to estimate the distribution of rotational velocities for the ONC stars at the age of the Pleiades (120 Myr). The modeled ONC and observed Pleiades distributions of rotation rates are not consistent if only stellar winds are included. In order to reconcile the observed loss of angu lar momentum between these two clusters, an extrinsic loss mechanism such as protostar-accretion disk interaction is required. Our model, which evolves the ONC stars with a mass dependent saturation threshold normalized such that ωcrit=5.4ω⊙\omega_{crit} = 5.4 \omega_\odot at 0.5 \m, and which includes a distribution of disk lifetimes that is uniform over the range 0--6 Myr, is consistent with the Pleiades. This model for disk-locking lifetimes is also consistent with inferred disk lifetimes from the percentage of stars with infrared excesses observed in young clusters. Different models, using a variety of initial period distributions and different maximum disk lifetimes, are also compared to the Pleiades. For disk-locking models that use a uniform distribution of disk lifetimes over the range 0 to τmax\tau_{max}, the acceptable range of the maximum lifetime is 3.5<τmax<8.53.5 < \tau_{max} < 8.5 Myr.Comment: 21 pages, 7 figures, submitted to Ap

    Social cognition in normal and pathological aging

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    The concept of social cognition refers to a set of skills and to emotional and social experiences regulating relationships between individuals. This concept is appropriate in order to help us to explain individual human behaviours and behaviours in groups. Social cognition involves social knowledge, perception and processing of social cues, and the representation of mental states. The concept of social cognition thus refers to a multitude of skills. This paper stops on several of them, namely theory of mind, empathy, moral reasoning, emotional processing and emotional regulation. We propose a conceptual approach to each of these skills also stopping on their cerebral underpinnings. We also make an inventory of knowledge about the effects of age and neurodegenerative diseases on social cognition

    Theory of mind, empathy and emotion perception in cortical and subcortical neurodegenerative diseases

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    Although the impact of neurodegenerative diseases on everyday interactions is well known in the literature, their impact on social cognitive processes remains unclear. The concept of social cognition refers to a set of skills, all of which are essential for living in a community. It involves social knowledge, perception and processing of social cues, and representation of mental states. This report is a review of recent findings on the impact of cortical and subcortical neurodegenerative diseases on three social cognitive processes, namely, the theory of mind, empathy and processing emotions. The focus here is on a conceptual approach to each of these skills and their cerebral underpinnings

    Blind fluorescence structured illumination microscopy: A new reconstruction strategy

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    In this communication, a fast reconstruction algorithm is proposed for fluorescence \textit{blind} structured illumination microscopy (SIM) under the sample positivity constraint. This new algorithm is by far simpler and faster than existing solutions, paving the way to 3D and/or real-time 2D reconstruction.Comment: submitted to IEEE ICIP 201
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