305 research outputs found

    Controlling the Spin Polarization of the Electron Current in a Semimagnetic Resonant-Tunneling Diode

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    The spin filtering effect of the electron current in a double-barrier resonant-tunneling diode (RTD) consisting of ZnMnSe semimagnetic layers has been studied theoretically. The influence of the distribution of the magnesium ions on the coefficient of the spin polarization of the electron current has been investigated. The dependence of the spin filtering degree of the electron current on the external magnetic field and the bias voltage has been obtained. The effect of the total spin polarization of the electron current has been predicted. This effect is characterized by total suppression of the spin-up component of electron current, that takes place when the Fermi level coincides with the lowest Landau level for spin-up electrons in the RTD semimagnetic emitter

    Determination of poloidal mode numbers of MHD modes and their radial location using a soft x-ray camera array in the Wendelstein 7-X stellarator

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    A forward modeling technique is developed for determining the characteristic features of observed MHD modes from the line-of-sight data of the soft x-ray (SXR) tomography diagnostics in the Wendelstein 7-X (W7-X) stellarator. In particular, forward modeling is used to evaluate the poloidal mode numbers m, radial location, poloidal rotation direction and ballooning character of the MHD modes. The poloidal mode structures have been modeled by the radially localized Gaussian-shaped emission regions rotating along the magnetic surfaces. In the present study the cases of rigid-shape emission regions and flexible emission regions are modeled. Various mode phase velocity dependences on the magnetic surface position are simulated. The modeled phase dynamics of line-integrated oscillations and the distribution of oscillation amplitudes are compared with the experimental signals of the SXR cameras which observe the plasma at various viewing angles in the poloidal cross-section. Application of this technique enables describing of the 1–50 kHz modes. In particular, in the discharge W7X-PID 20180918.045 three identified branches with the poloidal mode numbers m= 8, m= 10 and m= 11 localized at ρ ≈ 0.3 are rotating in the clockwise poloidal direction. The present paper reports the first application of the forward modeling technique to the data from the SXR diagnostics in W7-X. The high m-modes are identified by forward modeling in W7-X

    Behavior of the emission from atomic oxygen of the atmosphere at 557.7 nm during the events of stratospheric warming over East Siberia

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    The influence of stratospheric warming on the atomic oxygen emission at 557.7-nm wavelength (airglow) was investigated based on data obtained at the Geophysical Observatory of ISTP SB RAS (52°N, 103°E) in [1997][1998][1999][2000][2001][2002][2003][2004][2005]. In this period, several cases of anomalous behavior of the 557.7-nm emission intensity in the absence of strong geomagnetic disturbances have been recorded. It has been found that these cases of the growth of intensity of atmospheric emission at 557.7 nm in the height region of the mesosphere and lower thermosphere, have been caused by strong stratospheric warming when the disturbance covers a wide range of atmospheric altitudes. It should be emphasized that high concentration of centers of stratospheric warming is characteristic of Asia and, in particular, of the East Siberia that can result in the formation of regional peculiarities in characteristics of the airglow

    Cytosine-to-Uracil Deamination by SssI DNA Methyltransferase

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    The prokaryotic DNA(cytosine-5)methyltransferase M.SssI shares the specificity of eukaryotic DNA methyltransferases (CG) and is an important model and experimental tool in the study of eukaryotic DNA methylation. Previously, M.SssI was shown to be able to catalyze deamination of the target cytosine to uracil if the methyl donor S-adenosyl-methionine (SAM) was missing from the reaction. To test whether this side-activity of the enzyme can be used to distinguish between unmethylated and C5-methylated cytosines in CG dinucleotides, we re-investigated, using a sensitive genetic reversion assay, the cytosine deaminase activity of M.SssI. Confirming previous results we showed that M.SssI can deaminate cytosine to uracil in a slow reaction in the absence of SAM and that the rate of this reaction can be increased by the SAM analogue 5’-amino-5’-deoxyadenosine. We could not detect M.SssI-catalyzed deamination of C5-methylcytosine (m5C). We found conditions where the rate of M.SssI mediated C-to-U deamination was at least 100-fold higher than the rate of m5C-to-T conversion. Although this difference in reactivities suggests that the enzyme could be used to identify C5-methylated cytosines in the epigenetically important CG dinucleotides, the rate of M.SssI mediated cytosine deamination is too low to become an enzymatic alternative to the bisulfite reaction. Amino acid replacements in the presumed SAM binding pocket of M.SssI (F17S and G19D) resulted in greatly reduced methyltransferase activity. The G19D variant showed cytosine deaminase activity in E. coli, at physiological SAM concentrations. Interestingly, the C-to-U deaminase activity was also detectable in an E. coli ung+ host proficient in uracil excision repair

    Control and optimization of semi-passively actuated multibody systems

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    The controlled multibody systems are under the consideration. At the lecture special emphasis is put on the study of underactuated and overactuated systems having different type of actuators (external powered drives, unpowered spring-damper like drives, etc.). Several questions are addressed about the role of inherent dynamics, and how much multibody system should be governed by external powered drives and how much by the systems inherent dynamics. The lecture consists of the following parts: introduction to the subject in question; mathematical statement of the optimal control problems that are suitable for modelling of controlled motion and optimization of semi-passively controlled multibody systems with different degrees of actuation; description of the methodology and the numerical algorithms for solution of control and optimization problems for semi-passively actuated multibody systems. The solutions of several optimal control problems for different kind of semi-passively actuated multibody systems are presented. Namely, the energy-optimal control of planar semi-passively controlled three-link manipulator robot, the energy-optimal control of closed-loop chain semi-passively actuated SCARA-like robot; optimization of the hydraulic and pneumatic drives of the multibody system modelled the human locomotor apparatus with above-knee prostheses, and others. Future perspectives in area of control and optimization problems of the semi-passively actuated multibody systems are discussed

    Comprehensive analysis of the base composition around the transcription start site in Metazoa

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    BACKGROUND: The transcription start site of a metazoan gene remains poorly understood, mostly because there is no clear signal present in all genes. Now that several sequenced metazoan genomes have been annotated, we have been able to compare the base composition around the transcription start site for all annotated genes across multiple genomes. RESULTS: The most prominent feature in the base compositions is a significant local variation in G+C content over a large region around the transcription start site. The change is present in all animal phyla but the extent of variation is different between distinct classes of vertebrates, and the shape of the variation is completely different between vertebrates and arthropods. Furthermore, the height of the variation correlates with CpG frequencies in vertebrates but not in invertebrates and it also correlates with gene expression, especially in mammals. We also detect GC and AT skews in all clades (where %G is not equal to %C or %A is not equal to %T respectively) but these occur in a more confined region around the transcription start site and in the coding region. CONCLUSIONS: The dramatic changes in nucleotide composition in humans are a consequence of CpG nucleotide frequencies and of gene expression, the changes in Fugu could point to primordial CpG islands, and the changes in the fly are of a totally different kind and unrelated to dinucleotide frequencies
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