红光结合血卟啉单甲醚光动力疗法治疗微静脉畸形的实验研究

目的:通过鸡冠动物模型了解红光结合光敏剂血卟啉单甲醚(hematoporphyrin monomethylether,HMME)在光动力疗法治疗微静脉畸形中的治疗效果和适宜治疗参数。方法:48只鸡随机分组,处理组分别注射不同剂量的HMME后,半导体激光(红光)或氩离子泵浦染料激光不同能量密度分组照射,照射后肉眼和光镜下观察比较组织损伤程度并测量损伤深度。结果:红光结合HMME照射能引起鸡冠颜色变白、血管数量减少等形态学改变。HMME10mg/kg、15mg/kg剂量组中,在相同功率密度时,红光高能量密度照射组(240J/cm2)所造成损伤深度(分别为1.2225±0.8457mm,2.2800±1.3665mm)均显著大于氩离子泵浦染料激光不同能量密度的各照射组(P<0.05)。适宜治疗参数为HMME剂量10mg/kg,红光能量密度120-240J/cm2。结论:红光结合HMME光动力疗法有可能对增厚或结节型微静脉畸形实现更佳的治疗效果

改質之奈米碳管及其製法

本發明提供一種改質之奈米碳管,係於奈米碳管上接枝聚醚胺化 合物,使其表面之具有親/疏水性官能基;則不論於有機高分子或是水 中,皆能達到均勻分散的效果。本發明並提供改質奈米碳管之方法; 藉由酸化及氧化反應形成羧酸官能基,再經醯胺化反應及接枝反應得 到本發明之奈米碳管

中国脑血管病临床管理指南（第2版）（节选）——第5章 脑出血临床管理 Chinese Stroke Association Guidelines for Clinical Management of Cerebrovascular Diseases (Second Edition) (Excerpt) ——Chapter Five Clinical Management of Intracerebral Hemorrhage

自发性脑出血是卒中的一种严重亚型，在中国卒中患者中占23.4%，以急性发病、病情迅速变化以及高致死和致残率为显著特点。鉴于管理脑出血所面临的紧迫和复杂挑战，本指南旨在为其临床处理提供系统性和全面性的推荐意见。本章节覆盖了从脑出血院前评估、医疗干预到二级预防和康复的各个关键环节。在具体推荐方面，本指南根据不同的证据等级，为早期诊断、影像学评估、急性期干预、内科和重症监护、外科干预以及二级预防策略提供了指导，旨在全面提升自发性脑出血诊疗的科学性和系统管理质量。 Abstract: Spontaneous intracerebral hemorrhage represents a severe subtype of stroke, accounting for approximately 23.4% of stroke cases in China. It is characterized by its rapid onset, swift disease progression, and high rates of mortality and disability. Given the urgency and complexity in managing intracerebral hemorrhage, this guideline aims to provide systematic and comprehensive recommendations for its clinical management. This chapter covers all key aspects ranging from pre-hospital evaluation and medical intervention to secondary prevention and rehabilitation. With respect to specific recommendations, this guideline offers exhaustive guidance based on varying levels of evidence for early diagnosis, imaging assessments, acute-phase interventions, medical and ICU management, surgical interventions, and secondary prevention strategies, with the ultimate aim of enhancing the scientific rigor and systematic quality of spontaneous intracerebral hemorrhage management

古尔班通古特沙漠灌丛雾凇的生态水文学效应/Eco-Hydrological Effect of Shrub Rime in the Gurbantonggut Desert[J]

对生长于古尔班通古特沙漠东南边缘的梭梭和白梭梭两种植物的小枝与灌丛雾凇量进行了观测,并结合植被调查估算这两种植物对群落雾凇量的贡献量,探讨群落雾凇量与气象要素之间的关系.研究结果表明：在小枝水平上,白梭梭雾凇量是梭梭的1.5倍,但是在灌丛和群落尺度上,梭梭却是白梭梭的1.5和3.6倍.小枝粗细及其生长位置、灌丛形态结构和相对种群密度的差别共同造成两种植物雾淞量不同水平的差异.积雪、低风速、逆温和高湿是形成雾凇的最主要原因,日最高气温（Tma）与群落雾凇量（Rime）相关性最显著,它与日最小比湿（qmi）组成的二元线性方程可以解释Rime 98.50%的变异.在观测期,当Tma〉-11.48℃时,Rime随Tma的变化率较大,当Tma〈-11.48℃时,Rime随Tma的变化率较小,前者是后者的3.59倍.总之,雾凇能部分补偿雪面蒸发造成的积雪量减少,间接地保护了浅薄的地表积雪,是古尔班通古特沙漠冬季极重要的生态水文学过程

JUNO Sensitivity on Proton Decay p→νˉK+p\to \bar\nu K^+ Searches

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in $p\to \bar\nu K^+$ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar\nu K^+$ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is $9.6 \times 10^{33}$ years, competitive with the current best limits on the proton lifetime in this channel

JUNO sensitivity on proton decay p → ν K + searches*

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this study, the potential of searching for proton decay in the $p\to \bar{\nu} K^+$ mode with JUNO is investigated. The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar{\nu} K^+$ is 36.9% ± 4.9% with a background level of $0.2\pm 0.05({\rm syst})\pm$$0.2({\rm stat})$ events after 10 years of data collection. The estimated sensitivity based on 200 kton-years of exposure is $9.6 \times 10^{33}$ years, which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies