Design and Synthesis of Thiourea- and N-Aminothiourea-Based Neutral Receptors for Anion Recognition

分子识别是超分子化学研究的重要内容之一,它包括对中性分子、阳离子和阴离子的识别。其中阴离子识别较前两者发展相对迟缓,亟待丰富和发展新型识别体系。我们提出应用质子偶合电子转移(ProtonCoupledElectronTransfer,PCET)模型构筑识别阴离子的ICT(IntramolecularChargeTransfer)荧光载体；同时还依据基态电荷转移理论筛选特异性识别阴离子的生色离子载体,建立了系列灵敏度高、选择性好的阴离子光化学传感体系,实现了“裸眼”检测阴离子。论文将分四章介绍阴离子识别的发展状况,阐述本论文所建立的各类阴离子光化学传感体系及相关理论模型。 第一章简要介绍阴离子...Molecular recognition is an important research area in supramolecular chemistry. The development of anion coordination chemistry is delayed compared with neutral molecules and cations. It is therefore necessary to construct novel anion receptors. In this thesis, we constructed intamolecular charge transfer (ICT) fluorescence ionophores based on proton coupled electron transfer (PCET) model and chr...学位：理学博士院系专业：化学化工学院化学系_分析化学学号：B20002501

Thiourea-based Receptors for Anion Recognition and Sensing

[中文文摘]阴离子识别是超分子化学研究的重要内容之一 ,其关键环节是构筑可识别阴离子的结合受体 ,后者以非共价键力如静电作用、疏水作用、氢键等与阴离子结合。本文详细评述了近 5年来硫脲类阴离子识别受体的设计、结构及其阴离子识别作用的研究进展。[英文文摘]　Anion recognition and sensing have been developed into an important research subject in supramolecular chemistry. Noncovalent interactions such as hydrogen bonding , electrostatic interaction , hydrophobic interaction , etc.are the most important binding forces existing in the anion2receptor binding complexes , which forms the basis of designing anion binding receptors. The design , construction and anion recognition and sensing of thiourea2based receptors following mainly multi hydrogen bonding interactions are reviewed. 51 key references were cited to represent the related advances in the past 5 years.国家自然科学基金 (2 0 1 75 0 2 0 );福建省自然科学基金 (D0 2 2 0 0 0 1 )项目

Thiourea-based receptors for an on recognition and sensing

Anion recognition and sensing have been developed into an important research subject in supramolecular chemistry. Noncovalent interactions such as hydrogen bonding, electrostatic interaction, hydrophobic interaction, etc. are the most important binding forces existing in the anion-receptor binding complexes, which forms the basis of designing anion binding receptors. The design, construction and anion recognition and sensing of thiourea-based receptors following mainly multi hydrogen bonding interactions are reviewed. 51 key references were cited to represent the related advances in the past 5 years

长汀县赢坪史前遗址发掘简报

2012年福建博物院对赢坪两处遗址进行了抢救性考古发掘,获得了一批包括石器、陶器、铜器、石范等内涵丰富的文化遗物,这批遗物可进一步了解闽西地区的史前文化发展序列及文化面貌,并且对于多地区文化间的交流研究也有一定的作用

类泛素蛋白及其中文命名

泛素家族包括泛素及类泛素蛋白,约20种成员蛋白.近年来,泛素家族领域取得了迅猛发展,并已与生物学及医学研究的各个领域相互交叉.泛素家族介导的蛋白质降解和细胞自噬机制的发现分别于2004和2016年获得诺贝尔奖.但是,类泛素蛋白并没有统一规范的中文译名. 2018年4月9日在苏州召开的《泛素家族介导的蛋白质降解和细胞自噬》专著的编委会上,部分作者讨论了类泛素蛋白的中文命名问题,并在随后的\"泛素家族、自噬与疾病\"(Ubiquitinfamily,autophagy anddiseases)苏州会议上提出了类泛素蛋白中文翻译草案,此草案在参加该会议的国内学者及海外华人学者间取得了高度共识.冷泉港亚洲\"泛素家族、自噬与疾病\"苏州会议是由美国冷泉港实验室主办、两年一度、面向全球的英文会议.该会议在海内外华人学者中具有广泛影响,因此,参会华人学者的意见具有一定的代表性.本文介绍了10个类别的类泛素蛋白的中文命名,系统总结了它们的结构特点,并比较了参与各种类泛素化修饰的酶和它们的生物学功能.文章由45名从事该领域研究的专家合作撰写,其中包括中国工程院院士1名,相关学者4名,长江学者3名,国家杰出青年科学基金获得者18名和美国知名高校华人教授4名.他们绝大多数是参加编写即将由科学出版社出版的专著《泛素家族介导的蛋白质降解和细胞自噬》的专家

Recognition of Anion by Dual Fluorescent Sensor Based on the Intramolecular Charge Transfer in p-Dimethylaminobenzoylhydrazine

In t ramo lecu lar charge t ran sfer ( ICT ) dual f luo rescence of p 2dim ethylam ino2 benzoylhydrazine (DMABH ) in aceton it rile w as found to show a h igh ly select ive respon se to HSO -4 over several other an ions. The inten sity rat io of the CT to L E em ission and the to tal f luo rescence intensity of DMABH decreased with increasing bisulfate concent ration. While the dual f luo rescence respon se w as very sim ilar to that of DMABA at a low HSO4 concen t rat ion, the CT in ten sity decreased drast ically and the L E in ten sity rem ained almo st con stan t, how ever, the difference w as ob served at a h igh HSO -4 concen t rat ion, in w h ich bo th the CT and L E in ten sit ies of DMABH decreased. A different recogn it ion m echan ism f rom that of DMABA w as suggested fo r DMABH in w h ich hydrogen bonding and p ro ton izat ion w ere the recogn it ion in teract ion s at low and high HSO4 concen t rations,respectively.国家自然科学基金 (批准号 :2 0 175 0 2 0 );福建省自然科学基金重点课题 (批准号 :D0 2 2 0 0 0 1);教育部优秀青年教师奖 励计划 ( 2 0 0 1年 )和德国大众基金 (批准号 :I/770 72 )资助

Thermal conductivity of CNTs/paraffin phase change composites

Using multi-walled carbon nanotubes （MWCNTs） as the enhanced thermal conductivity fillers, CNTs/ paraffin composite phase change materials （PCMs） with various mass fractions （0. 1% -1.0% ） of CNTs are prepared by a two-step method. The effects of mass fr

碳纳米管/石蜡复合相变储能材料的导热性能研究

以多壁碳纳米管为填料，采用两步法制备了不同质量分数（0．1％～1．O％）的CNTs／石蜡复合相变材料。采用Hot—Disk热分析仪测试了CNTs／石蜡复合相变材料在不同纳米颗粒质量分数、温度和粒径下的导热系数。研究表明，CNTs／石蜡复合相变材料的固、液态导热系数随CNTs颗粒质量分数的增加而大幅度提高，在25℃时，质量分数为0．5％的复合相变材料的导热系数提高了13．2％，体现了良好的强化导热效果。复合相变材料的导热系数对温度的依赖性不强，但在55℃时，复合相变材料的导热系数在固一液相变过程时出现了较大程度的增长。此外，复合相变材料的导热系数随CNTs颗粒粒径的增加而降低，25℃时，质量分数为0．1％的复合相变材料中，添加10nm的碳纳米管后其导热系数提高了7．8％，添加100nm的碳纳米管后其导热系数提高了2．2％

Anion Recognition by N-Benzamido-N′-phenylthioureas inAqueous-Organic Binary Solvents

[中文文摘]设计合成了三种N 取代苯甲酰胺基 N′ 苯基硫脲 ,应用吸收光谱考察了CH3 CN以及 1%～ 10 %H2 O CH3 CN溶液中其与CH3 CO-2 ,H2 PO-4,HSO-4,ClO-4,Cl-和Br-等阴离子的相互作用 .结果表明 ,该类主体分子与阴离子形成氢键配合物 ,溶液由无色转变为黄色 .通过改变苯甲酰基上的取代基可有效调控识别结合作用的选择性 ,在含水介质中苯甲酰基上对乙氧基取代的主体分子可高选择性识别CH3 CO-2 .探讨了主客体之间的作用机理 ,并用于水相中无机醋酸盐的直接显色测定 .[英文文摘]　Three N2benzamido2N′2 phenylthiourea receptors were designed and synthesized and their interactions with anions such as CH3CO- 2 , H2PO-4 , HSO-4 , ClO-4 , Cl - and Br - in acetonitrile and acetonitrile2water binary solvents were investigated by using absorption spectroscopy. The results showed that hydrogen2bonding complexes were formed between receptors and anions , which turned the solution to yellow from colorless. It was found that the selectivity of receptors to anion could be efficiently tuned by increasing solvent polarity or by substitution at the N2benzoyl moiety. The recognition mechanism and binding mode were discussed and the anion recognition was successfully applied to inorganic CH3CO2NH4 in 10 % H2O2CH3CN. These findings are expected to be of significance for designing and developing novel color2based anion sensors operated in aqueous solution.国家自然科学基金 (Nos.2 99750 2 3;2 0 1 750 2 0 ) ;福建省自然科学基金 (No.D0 2 2 0 0 0 1 ) ;德国大众基金 (No .I/770 72 );教育部优秀青年教师奖励计划(2 0 0 1 )资助项目