Generalized Shifts on Cartesian Products

It is proved that if E, F are infinite dimensional strictly convex Banach spaces totally incomparable in a restricted sense, then the Cartesian product E×F with the sum or sup norm does not admit a forward shift. As a corollary it is deduced that there are no backward or forward shifts on the Cartesian product`p1×`p2,1\u3c p16=p2\u3c∞, with the supremum norm thus settling a problem left open in Rajagopalan and Sundaresan in J. Analysis 7 (1999(, 75-81 and also a problem stated as unsolved in Rassias and Sundaresan

Clinical significance of RRM1, CDX2 expression in different gastric mucosa lesions

目的探讨核苷酸还原酶亚单位M1（ribonucleotide reductase M1,RRM1）、尾型同源盒转录因子2（caudal-related homeobox transcription factor 2,CDX2）在不同胃黏膜组织中的表达,并分析其与胃癌发生发展及预后的关系。方法选取中国人民解放军第一七五医院病理科保存的组织蜡快240例,其中胃癌90例、高级别上皮内瘤变30例、低级别上皮内瘤变30例、肠上皮化生30例、浅表性胃炎30例、正常胃黏膜30例,采用S-P免疫组化方法检测6类不同胃黏膜组织RRM1、CDX2表达,进行临床病理相关性分析。结果正常胃黏膜、浅表性胃炎、肠上皮化生、低级别上皮内瘤变、高级别上皮内瘤变和胃癌中RRM1的阳性表达分别为40.0%、66.7%、33.3%、83.3%、83.3%、86.7%,胃癌、高级别上皮内瘤变、低级别上皮内瘤变组RRM1的阳性表达率均显著高于正常胃黏膜组与肠上皮化生组（P〈0.01）,亦高于浅表性胃炎组（P〈0.05）。CDX1的阳性表达分别为16.7%、0%、63.3%、33.3%、76.7%、61.1%,高级别上皮内瘤变、肠上皮化生、胃癌组的CDX2阳性表达率均显著高于浅表性胃炎组与正常胃黏膜组（P〈0.01）,高于低级别上皮内瘤变组（P〈0.05）。240例不同胃黏膜病变中,RRM1与CDX2之间表达呈正相关（rs=0.196,P=0.002）,90例胃癌中RRM1与CDX2之间呈正相关关系（rs=0.223,P=0.034）;RRM1、CDX2表达与肿瘤分化程度密切相关（P〈0.05）,CDX2表达与肿瘤浸润深度、淋巴结转移、TNM分期密切相关（P〈0.05）。结论 RRM1、CDX2表达均与胃癌的发生发展及预后有关,均可作为较为理想的肿瘤标志物,用于胃癌的早期诊断和转移的预警。Objective To explore the expression of ribonucleotide reductase M! （RRM1）and caudal- related homeobox transcription factor 2 （CDX2） in different gastric mucosa lesions and evaluate its relationship with the occurrence, development and prognosis of gastric cancer. Methods A total of 240 cases were selected from Department of Pathology of 175th Hospital of PLA, including 90 cases of gastric cancer,30 cases of highgrade intraepithelial neoplasia,30 cases of lowgrade intraepithelial neoplasia,30 cases of intestinal metaplasia, 30 cases of superficial gastritis, 30 cases of normal gastric mucosa. Expression of RRM1 and CDX2 was detected with immunohistochemistry SP method. Results The frequency of RRM1 expression were 86.7% ,83.3% and 83.3% in gastric cancer group, high - grade intraepithelial neoplasia group and low - grade intraepithelial neoplasia group, respectively. The frequencies were all higher than that in superficial gastritis group （66.7% ,P 〈0.05） and that in intestinal metaplasia group （33.3% ,P 〈0.01 ）. The frequency of RRM1 expression was higher in superficial gastritis group than that in intestinal metaplasia group（ P 〈 0.05 ）. The frequency of CDX2 expression were 76.7% ,63.3% and 61.1% in high - grade intraepithelial neoplasia group, intestinal metaplasia group and gastric cancer group, respectively. The frequencies were all higher than that in low - grade intraepithelial neoplasia group （33.3% ,P 〈 0.05 ） and that in superficial gastritis group （0%, P 〈 0.01 ）. In 240 cases of different gastric mucosa lesions, RRM1 expression was positively correlated with CDX2 expression（rs = 0. 196, P = 0. 002）. In 90 cases of gastric cancer, RRM1 expression was positively correlated with CDX2 （ r = 0. 223, P = 0. 034）. The expression of RRM1 and CDX2 were related with the differentiation degree （ P 〈 0.05 ）. CDX2 expression was related with the tumor invasion depth, TNM stages and the lymph node metastasis （P 〈 0.05）. Conclusion The expression of RRM1 and福建省教育厅B类科技基金资助项目（JB12319

Expression and clinical significance of RRM1,CDX2 in gastric cancer tissues

目的探讨RRM1、CDX2在胃癌组织中的表达,并分析其与胃癌侵袭与转移的关系。方法选取90例术前未行放化疗的胃癌石蜡标本及与其对应正常胃黏膜蜡标本30例,采用SP免疫组化方法检测RRM1和CDX2在两种组织中表达情况,分析二者表达与分化程度、浸润深度、淋巴结转移、TNM分期之间的关系。结果 （1）RRM1、CDX2在胃癌中的阳性表达率均显著高于正常胃黏膜组（86.7%vs 40.0%,P〈0.01;61.1%vs 16.7%,P〈0.01）。（2）90例胃癌中,RRM1与CDX2二者之间呈正相关关系（r_s=0.223,P=0.034）;RRM1、CDX2表达与分化程度密切相关（P〈0.05）,CDX2表达与浸润深度、淋巴结转移、TNM分期密切相关（P〈0.05）,RRM1表达与浸润深度、淋巴结转移、TNM分期无相关（P〉0.05）。结论 RRM1、CDX2可作为较为理想的肿瘤标志物,用于胃癌的诊断和预后的预警。Objective To explore the expression of RRM1 and CDX2 in gastric cancer tissues and its relationship with invasion and metastasis of gastric cancer. Methods Expression of RRM1 and CDX2 was detected in 90 cases of gastric cancer without preoperative chemoradiotherapy and 30 cases of normal gastric mucosa using immunohistochemistry SP method. The relationships of RRM1 and CDX2 expression with differentiation degree,tumor invasion depth,TNM stage and lymph node metastasis were analyzed. Results（1）The positive expression rates of RRM1 and CDX2 were both significantly higher in gastric cancer tissues than in those of normal gastric mucosa（86. 7% vs 40. 0%,P 〈 0. 01; 61. 1% vs 16. 7%,P 〈 0. 01）.（2） The expression of RRM1 in 90 cases of gastric cancer was positively correlated with CDX2（ r_s= 0. 223,P = 0. 034）. The expression of RRM1 and CDX2 was related with differentiation degree（ P〈 0. 05）. The expression of CDX2 was related with tumor invasion depth,TNM stage and lymph node metastasis（ P 〈 0. 05）. The expression of RRM1 was not related with tumor invasion depth,TNM stage,lymph node metastasis（ P 〉 0. 05）. Conclusion RRM1 and CDX2 can be used as ideal tumor markers in diagnosis of gastric cancer and prognosis.福建省教育厅B类科技基金资助项目（JB12319

现代黄河三角洲潮土水盐与野外光谱特征浅析

土壤水分、盐分时空变异强,是影响土壤光谱特征的两个重要因素。土壤水分、土壤盐分之间关系、土壤水分、盐分与土壤光谱特征之间关系如何直接关系到利用遥感光谱信息监测土壤盐渍化的精度。通过对在2007年10月利用Hydra土壤水分/盐分/温度三参数测试仪获得的现代黄河三角洲潮土水分、盐分数据和同点利用ASDFieldSpecRProFR便携式分光辐射光谱仪获得的潮土野外光谱同步测量数据进行了分析,探讨了现代黄河三角洲潮土10cm(包括潮土和盐化潮土两个亚类)水盐特征和土壤表面野外光谱特征之间的关系,结果表明:潮土中国科学院知识创新工程试点项目“结合水盐动态模型的现代黄河三角洲盐渍化土特征提取”(066U0303SZ)资

醋酸可的松合成中碘化反应工艺优化

以21-脱氧可的松(SSC)为原料、溴碘液为碘化剂,研究了SSC转化为一碘化物及一碘化物与二碘化物相互转化的反应过程,考察了摩尔比SSC/I2(溴碘液)、溴碘液滴加速度、反应时间、反应温度等因素对C-21位碘化反应的影响,以获得一碘化物为目标优化了反应工艺,采用高效液相色谱检测反应体系中一碘化物、二碘化物及SCC的浓度变化。结果表明,SSC转化为一碘化物与一碘化物转化成二碘化物为竞争反应,在溴碘液滴加结束的后续反应过程中二碘化物可以转化为一碘化物。生成一碘化物最多的最佳工艺条件为SSC/I2(溴碘液)摩尔比1:0.62、溴碘液滴加速度0.33 mL/min(SSC 20 g)、后续保温反应时间120 min、反应温度-3℃。该条件下醋酸可的松的平均摩尔收率为87.67%,比文献提高了14.93%

Theoretical Analysis of Buoyancy Effects in Thermoacoustic Oscillating Flow

热声交变流动是热声热机的工作基础，研究交变流动机理有助于人们认识热声热机的工作过程。鉴于前人的理论分析一般没有考虑浮力效应的影响，本文从流体热动力学的角度研究了浮力对流与热声交变流动的耦合规律。基于线性理论方法，给出了考虑浮力项和热对流Rayleigh数的热声线性理论模型，分析了浮力效应对平行交变流动的影响，发现热对流的存在明显影响交变流动速度分布及其“环形效应”

醋酸可的松合成中碘化反应工艺优化

以21-脱氧可的松(SSC)为原料、溴碘液为碘化剂,研究了SSC转化为一碘化物及一碘化物与二碘化物相互转化的反应过程,考察了摩尔比SSC/I2(溴碘液)、溴碘液滴加速度、反应时间、反应温度等因素对C-21位碘化反应的影响,以获得一碘化物为目标优化了反应工艺,采用高效液相色谱检测反应体系中一碘化物、二碘化物及SCC的浓度变化。结果表明,SSC转化为一碘化物与一碘化物转化成二碘化物为竞争反应,在溴碘液滴加结束的后续反应过程中二碘化物可以转化为一碘化物。生成一碘化物最多的最佳工艺条件为SSC/I2(溴碘液)摩尔比1:0.62、溴碘液滴加速度0.33 mL/min(SSC 20 g)、后续保温反应时间120 min、反应温度-3℃。该条件下醋酸可的松的平均摩尔收率为87.67%,比文献提高了14.93%