In-situ fabrication of Si/FeSi2@C NPs with volume control effect by fluidized bed chemical vapor deposition as anode materials

Silicon (Si) has been proven to be the most potential anode material for the next-generation lithium-ion batteries (LIBs) because of its superior theoretical capacity (similar to 4200 mAh g-1). However, the huge volume changes, unstable solid-state interphase (SEI) layers, and large internal stresses upon the lithiation process severely limit the practical application for commercial LIBs anodes. Herein, we fabricate the carbon-coated Si/FeSi2 nanoparticles (Si/FeSi2 @C NPs) with volume control effect by fluidized bed chemical vapor de-position (FBCVD) method to solve the above-mentioned problems. These 15 min-Si/FeSi2 @C NPs and 30 min-Si/FeSi2 @C NPs show excellent Li+ storage capacity in the first cycle (2705.9/3039.1 mAh g-1 and 2645.9/2984.2 mAh g-1) with high Initial Coulombic Efficiency (ICE) of similar to 89.0% and 88.7%. In-situ TEM characterization demonstrates that the carbon coating layer and inert FeSi2 phase enable a small volume variation, only similar to 37.8%, revealing the effective volume expansion control effect, and generating thin SEI layers. Besides, the perfect structure of Si/FeSi2 @C NPs makes this material a great improvement in rate performance.(c) 2022 Elsevier B.V. All rights reserved

Bioactive Peptide Nanodrugs Based on Supramolecular Assembly for Boosting Immunogenic Cell Death-Induced Cancer Immunotherapy

Immunogenic cell death (ICD)-induced immunotherapy holds promise for complete elimination and long-term protective immune responses against cancer by combining direct tumor cell killing and antitumor immune response. Some therapeutic approaches (such as hyperthermia, photodynamic therapy, or radiotherapy) and inducers (certain chemotherapy drugs, oncolytic viruses) have been devoted to initiating and/or boosting ICD, leading to the activation of tumor-specific immune responses. Recently, supramolecular assembled bioactive peptide nanodrugs have been employed to improve the efficacy of ICD-induced cancer immunotherapy by increasing tumor targeted accumulation as well as responsive release of ICD inducers, directly inducing high levels of ICD and realizing the simultaneous enhancement of immune response through the immune function of the active peptide itself. Here, the authors review bioactive peptide nanodrugs based on supramolecular assembly, mainly as an intelligent delivery system, a direct ICD inducer and an immune response enhancer, for boosting ICD induced cancer immunotherapy. The functions of diverse bioactive peptides used in the construction of nanodrugs are described. The design of a supramolecular assembly, the mechanism of boosting ICD, and synergetic effects of bioactive peptides combined immunotherapy are critically emphasized

A regenerative core-shell LTA@LDH adsorbent for indoor dehumidification and its improved adsorption performance

Dehumidification is vital for human health and environmental sustainability. However, traditional moisture adsorbents have the problems like low adsorption capacity, high regeneration energy consumption and negative impacts to environment. As a result, it is demanding to develop environmentally friendly adsorbents with desirable adsorption capacity and convenient regeneration. Herein, a Linde type A zeolite@Mg-Al layered double hydroxides (LTA@LDH) with core-shell structure is synthesized by a facile in-situ co-precipitation method and used for indoor dehumidification. The LTA@LDH with hierarchically porous structure presents advantageous synergism of micro-mesopores, and exhibits a better adsorption and desorption performance than the pure LTA. The whole water uptake capacity of LTA@LDH is 0.339 g.g- 1 in relative humidity 95 % & 30 degrees C, much higher than that of pure LTA (0.248 g.g(-1)). The desorption activated energy of LTA@LDH is 53.92 kJ.mol(-1), nearly half of pure LTA (88.63 kJ.mol(-1)), indicating its superior desorption performance. The adsorption activity of LTA@LDH remains unchanged after fifteen consecutive adsorption-regeneration cycles. Based on various characterizations, a three-stage dehumidification model of LTA@LDH was proposed to reveal its unique sorption behaviors: (1) capillary condensation mainly in LTA's micropores; (2) mono-layer order water absorbed in LDH's mesopores; and (3) multi-layer water absorbed in LDH's mesopores. This work provides a new approach to design and develop zeolite-based adsorbents by introducing LDH and designing unique core-shell structure