Research on Supplier Selection of Raw Materials for DL Customized Heavy Truck

在全球化市场日益扩大的背景下，产品生命周期缩短，产品外观和功能多样化，客户定制化服务需求日益增加，企业为了提高竞争力，迫切希望通过供应链的进一步整合和优化来满足并超越客户期望。如何解决产品数量过多，采购价值高，供应商资源分散的问题是这类定制产品制造企业亟待解决的问题。论文探讨了客户定制的小批量港口机械行业如何选择供应商的问题。论文首先从国内外供应商选择评估现状入手，对大批量生产方式和客户定制下供应链的不同特点进行综述。接着，论文探讨了DL公司客户定制的小批量港口机械零部件供应商的现状和成因。进一步，论文基于目前存在的问题提出了供应商选择的改进方案，研究通过供应商分级管理，发展基于长期合作的供应...In current economic trend of globalization, as enterprises are facing increasingly challenging with shorter life cycle products and with variable function and more customized demands, how to meet the needs of customer’s requirement is becoming a push in supply chain field by well management of raw material suppliers. This thesis started from the current supplier evaluation and selection theory, ma...学位：管理学硕士院系专业：管理学院_工商管理硕士(MBA)学号：1792011115072

Research on Supplier Selection of Raw Materials for DL Customized Heavy Truck

在全球化市场日益扩大的背景下，产品生命周期缩短，产品外观和功能多样化，客户定制化服务需求日益增加，企业为了提高竞争力，迫切希望通过供应链的进一步整合和优化来满足并超越客户期望。如何解决产品数量过多，采购价值高，供应商资源分散的问题是这类定制产品制造企业亟待解决的问题。论文探讨了客户定制的小批量港口机械行业如何选择供应商的问题。论文首先从国内外供应商选择评估现状入手，对大批量生产方式和客户定制下供应链的不同特点进行综述。接着，论文探讨了DL公司客户定制的小批量港口机械零部件供应商的现状和成因。进一步，论文基于目前存在的问题提出了供应商选择的改进方案，研究通过供应商分级管理，发展基于长期合作的供应...In current economic trend of globalization, as enterprises are facing increasingly challenging with shorter life cycle products and with variable function and more customized demands, how to meet the needs of customer’s requirement is becoming a push in supply chain field by well management of raw material suppliers. This thesis started from the current supplier evaluation and selection theory, ma...学位：管理学硕士院系专业：管理学院_工商管理硕士(MBA)学号：1792011115072

High-speed communication interface based on SOPC

基于fPgA的可编程片上系统(SOPC)以其设计灵活、可裁剪、软硬件可在线编程等特点和优势,成为嵌入式系统设计,乃至电子领域发展的一个重要方向。用户IP核的设计是SOPC设计的重要组成部分,介绍了通信系统的SOPC系统架构,提出利用IPIf将用户IP核挂载到Plb总线上的方法,给出了rlC和物理层接口的IP核的设计与实现。设计中首先把IPIf信号转换成用户逻辑的内部信号,同时对不同速率的接口进行数据缓存,实现流水线传输,从而提高传输速率。FPGA-based Programmable System on Chip(SoPC)with its flexible design,scalable,hardware and software online programming and other features and advantages,becomes an important direction of the embedded system design,and even the development of electronic.User IP core design is an important part of SoPC design.The paper first briefly introduces the SoPC architecture of communication system,and then makes use of IPIF to mount the user IPcore to the PLB bus,at last gives the design and implementation of RLC and PHY Layer interface IP core.In the design,first transfer the IPIF signals into the user logic internal signal,and then cache data of the interface of different rates,to realize the pipelined transmission and improve the transmission speed.福建省重大专项项目资助(2009HZ0003-1

A New Comparison Principle for Impulsive Functional Differential Equations

通过归纳总结建立了一种关于具有有限时滞的脉冲泛函微分方程的新的比较原理,并利用这种比较原理,得到了几个时滞脉冲微分方程稳定性的充分条件。最后举出了一个例子来说明研究结果的有效性。In this paper,we establish a new comparison principle for impulsive differential systems with time delay,then,using this comparison principle,we obtain some sufficient conditions for several stabilities of impulsive delay differential equations.Finally,we present an example to show the effectiveness of our results

Phytoplankton community structures revealed by pigment signatures in Norwegian and Greenland Seas in summer 2012

对2012年中国第5次北极科学考察期间的挪威海和格陵兰海两个断面的光合色素进行了高效液相色谱(HPlC)分级分析,通过藻类色素化学分类分析软件(CHEMTAX)获得了不同浮游植物类群对叶绿素A的贡献,进而得到该海域表层和次表层(30 M)的浮游植物群落结构。结果表明:表层总叶绿素A的浓度为23.59 ng/l,低于次表层的30.38 ng/l,其中浮游植物根据粒径划分对总叶绿素A的贡献由高到低依次是微型浮游植物、小型浮游植物和微微型浮游植物。该海域同时存在葱绿叶绿素(PrASInO)、墨角藻黄素(fuCO)、别藻黄素(AllO)、多甲藻素(PErId)、玉米黄素(zEA)、19-丁墨甲藻黄素(19'bf)和19-六已墨甲藻黄素(19'Hf)等色素,其浓度和分布与温盐和营养盐等环境因子存在一定的相关性。不同粒径浮游植物色素组成显示,微微型浮游植物群落中以S型定鞭藻(28%)、n型定鞭藻(21%)、硅藻(18%)和青绿藻(12%)占优;微型浮游植物群落的优势类群为S型定鞭藻(53%)、n型定鞭藻(20%)和硅藻(12%);而小型浮游植物群落主要为硅藻(63%)和甲藻(17%)。Composition of phytoplankton controlled not only the formation of the Food Chain,but also the efficiency of energy transfer.At the same time,phytoplankton influenced the distribution of nutrient and the sedimentation of organic particulate matter.So study of phytoplankton community structures plays an important role in understanding the ecological function of phytoplankton.Photosynthetic pigments needed by photosynthesis,are very good biomarkers.They can be used to research and characterize phytoplankton community structure.Norwegian and Greenland Seas which are influenced by the Arctic water with low temperature and salinity and Atlantic water with high temperature and salinity.Understanding of correlation between environmental factors and phytoplankton community structure,is important for understanding the community structure of the marine organisms and their ecological function.During the 5thChinese Arctic Research Expedition in summer 2012,we analyze the photosynthetic pigments fromNorwegian and Greenland Seas by HPLC.Contributions of different phytoplankton assemblages to Chlorophyll a were obtained by Chemical Taxonomy( CHEMTAX),and thus resulted in composition of the phytoplankton community structure at the surface and subsurface water( about 30 m depth).The result showed that average concentration of Chlorophyll a at surface water was 23.59 ng / L,lower than that at upper water( 30.38 ng / L).The contributions of phytoplankton to Chlorophyll a were nano-> micro-> pico-one.Prasinoxanthin,Fucoxanthin,Alloxanthoxyletin,Peridinin,Zeaxanthin,19'-but-fucoxanthin,19-hexanoyloxyfucoxanthin were observed in the waters.Their distributions were relative to environmental factors,including Nutrients,temperature and salinity.These photosynthetic pigments showed negative correlations with temperature and salinity.Whereas they showed positive relations with nutrients,including NO-2,NO-3,SiO3 2-and PO3-4.The correlations of different phytoplankton and environmental factors were different.Diatoms had a very significant positive correlation with SiO3 2-,but had no correlation with PO3-4,NO-2and NO-3; Haptophytes-N had significant positive correlations with PO3-4,NO-2and NO-3; Haptophytes-S also had a positive correlation with PO3-4,but had no correlation with NO-2and NO-3.The maximum values of these photosynthetic pigments,except for Zea and Fuco,existed in the subsurface of the section BB.The distribution and concentration of photosynthetic pigments could explain the distribution and abundance of the phytoplankton to some extent.Not only because the pigments are complex and multiple,but also because there are inevitable errors in the testing and sampling,we cant determine the existence and abundance of the phytoplankton.So we use the CHEMTAX to obtain the contributions of different phytoplankton assemblages to Chlorophyll a,and thus resulted in composition of phytoplankton community structure.The composition of phytoplankton showed that Haptophytes-S( 28%), Haptophytes-N( 21%),Diatoms( 18%),and Prasinophytes( 12%) were main assemblages in the picoplankton; the main composition of nanophytoplankton were Haptophytes-S( 53%),Haptophytes-N( 20%),and Diatoms( 12%); meanwhile, Diatoms( 63%) dominated the microphytoplankton,followed by Dinoflagellates( 17%).Haptophytes-S,Haptophytes-N and Diatoms were dominant species in the surface and subsurface of section BB and AT belonging to the Norwegian and Greenland Sea.If Fucoxanthins and Diatomss existence in picophytoplankton could explain the tendency of phytoplankton to micro and miniaturization,these still need to be more sufficient evidence.国家自然科学基金(41076130;41206189); 南北极环境综合考察与评价专项(CHINARE2011-2015

三种检测方法对样品中沙门氏菌的检测结果比较

本实验采用VIDAS、API20E和SN0170-92三种不同的检测方法对CNCA举行的食品中常见致病菌能力验证计划中提供的一份盲样进行检验,总结对比了3种不同检验方法对沙门氏菌检测的各自优缺点

反相高效液相色谱法分析盘基网柄菌对氨基酸的利用

为观察盘基网柄菌(Dictyostelium discoideum)在SIH培养基上对氨基酸的利用情况,以2,4-二硝基氯苯为衍生化试剂,研究了用反相高效液相色谱(RP-HPLC)测定氨基酸的方法.在60min内16种氨基酸达到基线分离,峰面积与氨基酸浓度的线性相关系数为0.992～0.999.对发酵液样品的分析结果表明,盘基网柄菌对赖氨酸的利用最为彻底,发酵后期赖氨酸已被消耗完全.蛋氨酸、色氨酸、精氨酸、组氨酸也较易被盘基网柄菌利用,而对天冬氨酸、谷氨酸、甘氨酸、苏氨酸、脯氨酸、缬氨酸的需求不大.这一代谢特点为改进盘基网柄菌培养基组成提供依据

Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta

Dermal immature adipocytes fightagainstStaphylococcusaureusinfectionby secreting antimicrobial peptidesduring adipogenesis. Zhang et al.demonstrate that activation of the TGF-bpathway suppresses the adipogenicpotential of dermal fibroblasts andtherefore leads to an age-dependent lossof antimicrobial protection fromdermal fat. 皮下脂肪细胞作为皮肤的最后一道防线，有很重要的免疫抗菌功能，分化中脂肪细胞释放大量抗菌肽，这是一种人自源抗生素，能有效地抑制细菌生长。但这一重要的宿主天然免疫功能在发育和老化过程中如何被调控还不为人知。研究人员发现，老化过程中皮肤脂肪丢失是和真皮成纤维细胞（dermal fibroblasts）失去脂肪分化能力密切相关的。真皮成纤维细胞是皮肤深处的特化细胞，可以产生结缔组织并帮助皮肤从损伤中恢复。【Abstract】Dermal fibroblasts (dFBs) resist infection by locallydifferentiating into adipocytes and producing cathe-licidin antimicrobial peptide in response toStaphylo-coccusaureus(S.aureus). Here, we show thatneonatal skin was enriched with adipogenic dFBsand immature dermal fat that highly expressed cath-elicidin. The pool of adipogenic and antimicrobialdFBs declined after birth, leading to an age-depen-dent loss of dermal fat and a decrease in adipogene-sis and cathelidicin production in response to infec-tion. Transforming growth factor beta (TGF-b),which acted on uncommitted embryonic and adultdFBs and inhibited their adipogenic and antimicro-bial function, was identified as a key upstream regu-lator of this process. Furthermore, inhibition of theTGF-breceptor restored the adipogenic and antimi-crobial function of dFBs in culture and increasedresistance of adult mice toS.aureusinfection. Theseresults provide insight into changes that occur in theskin innate immune system between the perinataland adult periods of life.This work was supported by NIH grant R01-AR069653 to L.Z. and R.L.G. and NIH grants R01-AI083358, R01-AR052728, and U19-AI117673 to R.L.G. M.V.P. is supported by a Pew Charitable Trust grant, NIH grants U01-AR073159 and R01-AR067273, National Science Foundation (NSF) grant DMS1763272, and Simons Foundation grant 594598 (to Qing Nie). C.F.G.J. is supported by NSF-GRFP grant DGE-1321846 and MBRS-IMSD training grant GM055246. Y.Z. is supported by NIH grant R01-AI107027. 该项目研究得到了厦门大学双一流启动基金的支持

一种基于微电极的珊瑚共生体光补偿点测定方法探讨

珊瑚虫与虫黄藻互利共生形成共生体,虫黄藻通过光合作用为珊瑚虫提供重要的能量来源。珊瑚共生体的光补偿点可以较好地指示珊瑚的光适应性,是重要光合特性指标,但其测定方法鲜有报道。利用溶氧微电极结合光强可调节光源,以鹿角杯形珊瑚为实验材料,依据扩散平衡理论,建立了一种造礁石珊瑚的光补偿点的测定方法。实验结果表明珊瑚的扩散边界层溶氧浓度会快速响应光强变化。珊瑚扩散边界层溶氧浓度与光合有效辐射具有较好的相关性,且光强由高降低过程测得的相关系数更高。实验测得鹿角杯形珊瑚的光补偿点较低,为1.52μE/m~2/s,与喜阴植物的光补偿点相当。相对较低的光补偿点利于珊瑚栖居于水深范围更广的区域,有助于扩展珊瑚的生态位。溶氧微电极相关技术和方法在珊瑚光合作用研究中具有广泛的应用前景。中国科学院战略性先导科技专项A(XDA13020300)国家自然科学基金(41676163; 41406191; 41276113; 41276114)国家重点研发计划(2017YFC0506301,2018YFC1406500)广州市珠江科技新星(201806010017

基因编辑的法律与伦理问题

跨域同仁聚焦公共话题,本辑围绕基因编辑的法律与伦理议题,各位学者基于不同的立场与视角做出不同的评议。为尊重言论,兹实录对话,仅做最低限度的技术处理