331 research outputs found

    Uloga Jeanne Lanvine u modi 20.stoljeća i pitanje revitalizacije njezinog opusa

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    Završni rad sastoji se od uvoda i razrade teme podijeljene u nekoliko poglavlja. Uvodni dio služi za definiranje teme, provedenom istraživanju o temi i ciljevima, opisana je i metoda rada te su navedeni autori i literature koji su korišteni tijekom istraživanja teme. Razrada teme započinje biografijom Jeanne Lanvin, od rođenja, tokom godina njenog rada pa sve do smrti. Istraživani su njeni najutjecajniji dizajni, uz koje su priložene slike, utjecaji kojima se koristila prilikom dizajniranja, priča iza loga modne kuće Lanvin, inovacije koje donosi u svijet mode te njen utjecaj na modni svijet. Posebno poglavlje služi za istraživanje drugih aspekata karijere u životu Jeanne Lanvin i svestranost i osebujnost njenoga rada te kreativnosti. Pobliže sam se fokusirala na vrste haljina/dizajna koji su se najviše isticali u njenim kreacijama. Revitalizacija i utjecaj rada Jeanne Lanvin na druge dizajnere opisana je u idućem poglavlju, te je ovo poglavlje podijeljeno na revitalizaciju kroz rad budućih dizajnera koji su naslijedili tu poziciju u modnoj kući Lanvin i na revitalizaciju i inspiraciju kod ostalih dizajnera. Naposlijetku, iznosi se zaključak donesen o temi ovog završnog rada i o rezultatima dobivenim tokom istraživanja. Navedena je literatura i autori.Bachelor dissertation consists of introduction and theme elaboration sectioned into several chapters. Introductory part serves for defining the theme, research that has been done on this subject and research goals, work method has been described as well as authors and literature that has been used for research has been listed. Theme development begins with Jeanne Lanvin biography, since the birth, trough the years of her work all up to death. Most influential designs made by her were researched, backed up with pictures, influences for her designs, the story behind the Lanvin house logo, and the innovations that she had brought to the world of fashion. Seperate chapter serves for research of other career aspects in life of Jeanne Lanvin and versatility and distinctiveness of her work and her creativity. I focused more on the types of dresses that stood out the most in her designs. Revitalization and influence of Jeanne Lanvin's work on other designers was worked on in the next chapter, wich is divided into revitalization through the work of the future designers in the Lanvin house and revitalization in other designers work. Lastly, the conclusion about this dissertation is made, as well as results obtained throughout researching of this subject. Literature and authors are listed at the end

    The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster.

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    Despite decades of work, our understanding of the distribution of fitness effects of segregating genetic variants in natural populations remains largely incomplete. One form of selection that can maintain genetic variation is spatially varying selection, such as that leading to latitudinal clines. While the introduction of population genomic approaches to understanding spatially varying selection has generated much excitement, little successful effort has been devoted to moving beyond genome scans for selection to experimental analysis of the relevant biology and the development of experimentally motivated hypotheses regarding the agents of selection; it remains an interesting question as to whether the vast majority of population genomic work will lead to satisfying biological insights. Here, motivated by population genomic results, we investigate how spatially varying selection in the genetic model system, Drosophila melanogaster, has led to genetic differences between populations in several components of the DNA damage response. UVB incidence, which is negatively correlated with latitude, is an important agent of DNA damage. We show that sensitivity of early embryos to UVB exposure is strongly correlated with latitude such that low latitude populations show much lower sensitivity to UVB. We then show that lines with lower embryo UVB sensitivity also exhibit increased capacity for repair of damaged sperm DNA by the oocyte. A comparison of the early embryo transcriptome in high and low latitude embryos provides evidence that one mechanism of adaptive DNA repair differences between populations is the greater abundance of DNA repair transcripts in the eggs of low latitude females. Finally, we use population genomic comparisons of high and low latitude samples to reveal evidence that multiple components of the DNA damage response and both coding and non-coding variation likely contribute to adaptive differences in DNA repair between populations

    Evidence that natural selection maintains genetic variation for sleep in Drosophila melanogaster.

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    BackgroundDrosophila melanogaster often shows correlations between latitude and phenotypic or genetic variation on different continents, which suggests local adaptation with respect to a heterogeneous environment. Previous phenotypic analyses of latitudinal clines have investigated mainly physiological, morphological, or life-history traits. Here, we studied latitudinal variation in sleep in D. melanogaster populations from North and Central America. In parallel, we used RNA-seq to identify interpopulation gene expression differences.ResultsWe found that in D. melanogaster the average nighttime sleep bout duration exhibits a latitudinal cline such that sleep bouts of equatorial populations are roughly twice as long as those of temperate populations. Interestingly, this pattern of latitudinal variation is not observed for any daytime measure of activity or sleep. We also found evidence for geographic variation for sunrise anticipation. Our RNA-seq experiment carried out on heads from a low and high latitude population identified a large number of gene expression differences, most of which were time dependent. Differentially expressed genes were enriched in circadian regulated genes and enriched in genes potentially under spatially varying selection.ConclusionOur results are consistent with a mechanistic and selective decoupling of nighttime and daytime activity. Furthermore, the present study suggests that natural selection plays a major role in generating transcriptomic variation associated with circadian behaviors. Finally, we identified genomic variants plausibly causally associated with the observed behavioral and transcriptomic variation

    Impact of UV radiation on the physical properties of polypropylene floating row covers

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    In the intensive horticulture, various ways of protected area are used for the growth of seedlings and the cultivation of vegetables in all seasons. The easiest and the cheapest form of protected area is agrotextile, which can be laid directly over vegetable crops (row cover). Agrotextiles are nonwovens which are manufactured from textile fibres which are usually of chemical origin. Textiles, used as agrotextiles require suitable tensile strength and good permeability characteristics with no significant deterioration under the influence of weather changes and UV radiation. Properties of agrotextiles depend on the fibres made of and on the type and conditions of production. The purpose of this study was to analyse the influence of simulated sun light radiation (xenon lamp) on physical properties of polypropylene (PP) nonwoven material, which is used for the production of agrotextiles. The research showed that the properties of row cover change when radiated with UV light. Tensile, tearing and bursting properties worsen after radiation and air permeability and water vapour show little increase. The changes in the properties are a consequence of changes in fibres, molecular and supermolecular structure which is exhibited in changed fibres and consequently also nonwoven properties.Key words: Agrotextile, polypropylene, nonwovens, UV radiation, properties

    Endovascular treatment of aneurysms and pseudoaneurysms of the visceral branches of the abdominal aorta

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    Poboljšanje slikovnih dijagnostičkih metoda u posljednjih nekoliko desetljeća dovelo je do povećanja frekvencije otkrivanja asimptomatskih aneurizmi visceralnih arterija. Jednako tako, sve učestalija primjena perkutanih interventnih postupaka dovela je do veće incidencije pseudoaneurizmi. Ipak, aneurizme visceralnih arterija su relativno rijetka stanja, no, zbog oslabljene stijenke proširenog dijela krvne žile, sklone su rupturi koju prati krvarenje u 22% slučajeva s mortalitetom od 8.5%. Tradicionalno vaskularna kirurgija u liječenju primjenjuje otvoreni pristup s resekcijom aneurizme sa ili bez uspostave kontinuiteta arterije ili resekcijom distalnog organa, poput slezene. No te metode nije uvijek moguće primijeniti. U slučajevima pratećeg peritonitisa ili pankreatitisa, u pacijenata s prijašnjim abdominalnim operacijama ili multiplim komorbiditetima, otvoreni pristup je otežan i praćen većim morbiditetom i mortalitetom. Sve učestalija upotreba minimalno invazivnih endovaskularnih tehnika je dobra alternativa u tim indikacijama. Endovaskularna embolizacija zavojnicama i tekućim materijalima, postavljanje stent graftova i multilayered stentova se primjenjuje sve češće kako se interventna radiologija razvija. Glavne prednosti takvih transkateterskih metoda su minimalna invazivnost, manja postoperativna bol, niža stopa komplikacija, kraća hospitalizacija i brži povratak pacijenta svakodnevnim aktivnostima.In the last few decades, advanced imaging techniques have led to increased detection of asymptomatic visceral artery aneurysms. Also, increased percutaneous endovascular interventions have raised the incidence of iatrogenic pseudoaneurysm formation. Still, aneurysms of visceral arteries are a rare condition, but, due to the weakness of dilated blood vessel wall, they are prone to rupture, resulting in life-threatening hemorrhage in 22% of cases with mortality of 8.5%. Traditional vascular surgery management involves an open exposure to excise the aneurysm with or without re-establishment of vascular continuity or end organ resection (e.g. spleen). However, these methods are not applicable in every case. In cases of concomitant peritonitis or pancreatitis, in patients with previous abdominal surgery or multiple comorbidities, the open repair becomes difficult and carries a higher morbidity and mortality. The rising use of minimally invasive endovascular techniques over the past decade offers a good alternative in these indications. Endovascular coiling, liquid embolization, placement of covered and multilayered stents are becoming more and more common as the intervention radiology develops. The main advantages of this catheter-based methods are minimal invasiveness, less post-operative pain, less complications, shorter hospitalization and sooner incorporation in the everyday activities

    Validation of Elmendorf Method for Testing Perforated Corrugated Cardboard

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    The Elmendorf method is a well-known test that provides valuable insight into the durability and lifespan characteristics of the observed material, i.e., paper or paperboard. The objective of this paper is to determine if it is possible to apply the Elmendorf test to perforated corrugated cardboard to measure tear resistance. An Instron tensile tester was used to obtain input data for a range of properties of perforated corrugated board and to validate the non-standard test technique. Correlation analysis was used to statistically verify and quantify the relationship between the results obtained by the two aforementioned methods. Specimens were cut from four different qualities of three-layer E-flute corrugated cardboards at five defined angles affected by five types of perforations. First, the graphical difference in Least Square mean values was analysed and the results were confirmed by correlation analysis. No significant difference in results between the two observed methods was determined, and the relationship was mostly interpreted as a high positive correlation. Therefore, the results obtained by the Elmendorf method can be used for a better understanding of the mechanical properties of perforated corrugated cardboard

    Inactivation of the SGS1 and EXO1 Genes Synergistically Stimulates Plasmid Integration in Yeast

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    Different procedures used for targeted genetic manipulations are based on homologous recombination between chromosomal and exogenous DNA. A double-strand break (DSB) present on the plasmid molecule stimulates and directs plasmid integration to the homologous sequence in the yeast genome and we wondered whether this process could be further enhanced in selected DNA repair mutants. In order to compare the results obtained in different yeast strains, the efficiency of transformation with a linear integrative plasmid was compared to that obtained with a circular replicative plasmid. With respect to the wild type, the relative efficiency of transformation was increased in the sgs1 and exo1 mutants and decreased in the rad1 and srs2 mutants. Inactivation of the SGS1 or EXO1 gene stimulated plasmid integration 4- to 5-fold, while 15-fold increase was observed in the double sgs1 exo1 mutant. This result indicates that the two proteins participate in different cellular processes that limit plasmid integration in the wild type yeast. Southern blot analysis of 20 transformants obtained in the double mutant confirmed that they occurred by homologous integration to the target sequence. Homologues to both EXO1 and SGS1 genes have been found in other organisms and we suggest that their inactivation may also lead to enhanced gene targeting

    ISKORIŠTAVANJE KOGNITIVNIH PRISTRANOSTI U SVRHU MANIPULACIJE POTROŠAČIMA

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    U radu se analiziraju načini na koji marketinški stručnjaci iskorištavaju kognitivne pristranosti u svrhu marketinške komunikacije i time utječu na izbor potrošača. Definiraju se teorijski aspekti u vezi s ponašanjem potrošača i čimbenika koji utječu na takvo ponašanje. Daje se uvid u podložnosti potrošača heuristikama i pristranostima prilikom odluke o kupnji te prikazuju mogućnosti iskorištavanja kognitivnih pristranosti u marketingu. Rezultati provedenog istraživanja anketnim upitnikom pokazali su da tvrtke iskorištavaju kognitivne pristranosti u marketinške svrhe s ciljem saznavanja i dobivanja uvida u novije oblike marketinškog manipuliranja potrošačima. Na kraju je izveden sveobuhvatan zaključak rada.This paper analyzes the ways in which marketers exploit cognitive bias for the purpose of marketing and thus affect consumer choice. It defines the theoretical aspects related to consumer behaviour and the factors affecting influence. It gives an insight into the susceptibility of consumers heuristics and biases regarding purchasing decisions and shows the possibilities of exploitation of cognitive biases in marketing. Research findings have shown that companies exploit cognitive bias in marketing with the aim of finding and gaining insights into new forms of consumer manipulation. At the end comprehensive conclusion of work is derived
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