Analysis of Performance of Dynamic Multicast Routing Algorithms

In this paper, three new dynamic multicast routing algorithms based on the greedy tree technique are proposed; Source Optimised Tree, Topology Based Tree and Minimum Diameter Tree. A simulation analysis is presented showing various performance aspects of the algorithms, in which a comparison is made with the greedy and core based tree techniques. The effects of the tree source location on dynamic membership change are also examined. The simulations demonstrate that the Source Optimised Tree algorithm achieves a significant improvement in terms of delay and link usage when compared to the Core Based Tree, and greedy algorithm

A Unified Software Architecture to Enable Cross-Layer Design in the Future Internet

Abstract—While research on cross-layer network optimization has been progressing, useful implementations have been lagging because the current Internet architecture does not accommodate cross-layering gracefully. As part of our FIND project, we propose a software architecture for the future Internet that is designed to accommodate such interactions. We present a conceptual overview as well as high level software design and an early prototype implementation, and point out the strengths of our architecture. I

Implication of genetic variants in overweight and obesity susceptibility among the young Arab population of the United Arab Emirates

© 2020 Elsevier B.V. Objective: Overweight and obesity are major risk factors for Type 2 Diabetes Mellitus (T2DM), cardiovascular disease (CVD) and cancer. Genetic predisposition has been shown to play a key role in obesity, and genome-wide association studies (GWAS) have identified multiple loci linked with obesity in various ethnic groups. The aim of this study was to validate the reported genetic variants associated with obesity and overweight in a young UAE Arab population. Methods: Twenty-two associated single nucleotide polymorphisms (SNPs) at 11 loci (FTO, MC4R, TMEM18, KCTD15, MTCH2, SH2B1, TFAP2B, GNPDA2, NEGR1, PCSK1 and BDNF) were studied in 392 controls and 318 overweight/obese young Emiratis (aged 18–35 years). Results: After adjusting for age and smoking, rs3751812 of the FTO gene was associated with overweight/obesity in male participants (p-value \u3c 0.016), while SNPs rs17782313, rs571312 of the MC4R gene and rs12463617 of the TMEM18 gene were significantly associated with overweight/obesity in female participants (p-value = 0.001, 0.028, 0.044, respectively). Follow-up association tests and logistic regression revealed the contribution of the FTO rs3751812 and MC4R rs571213 SNPs to the risk of overweight/obesity after adjusting for age, sex and smoking (p-value = 0.044, 0.049, respectively). In addition, the FTO rs3751812 was associated with the risk of overweight/obesity after adjusting for the effect of other markers (rs17782313, rs571312, rs2867125, rs6548238 and rs12463617) (p-value = 0.035). A significant gene-gene interaction was seen between FTO, MCR4 and TMEM18 (p-value = 0.013). Conclusions: Our data demonstrates that rs3751812 of the FTO gene is the key SNP associated with risk of overweight/obesity among the young UAE Arab population, in alignment with previous findings. Our results also indicate that the identified genes stratify with sex and risk of overweight/obesity. In addition to their direct association with overweight/obesity, rs17782313 and rs571312, as well as rs2867125 and rs6548238, may have a modifying effect on the risk of overweight/obesity caused by the rs3751812. Population-specific, sex-specific genetic profiling is important in understanding the heritability of obesity

Multicast Capacity of Optical WDM Packet Ring for Hotspot Traffic

Packet-switching WDM ring networks with a hotspot transporting unicast, multicast, and broadcast traffic are important components of high-speed metropolitan area networks. For an arbitrary multicast fanout traffic model with uniform, hotspot destination, and hotspot source packet traffic, we analyze the maximum achievable long-run average packet throughput, which we refer to as \textit{multicast capacity}, of bi-directional shortest-path routed WDM rings. We identify three segments that can experience the maximum utilization, and thus, limit the multicast capacity. We characterize the segment utilization probabilities through bounds and approximations, which we verify through simulations. We discover that shortest-path routing can lead to utilization probabilities above one half for moderate to large portions of hotspot source multi- and broadcast traffic, and consequently multicast capacities of less than two simultaneous packet transmissions. We outline a one-copy routing strategy that guarantees a multicast capacity of at least two simultaneous packet transmissions for arbitrary hotspot source traffic