Mediation Effect of Lean: A Bidirectional Synergetic Relationship with SCM for Higher Operational Performance

Competitive plants focus their efforts on reducing manufacturing costs and waste along their production chains. Hence, manufacturing programs with important practices and methodologies such as lean, JIT, TPM, and Kaizen have been embraced. However, an empirical investigation of simultaneous use of several manufacturing programs representing multiple facets of lean is lacking in the literature. Various studies have found that some supply chain management practices are bi-directionally related to lean, but its holistic measurement in relation to supply chain management is still lacking. Thus, this paper provides an evidence of mediation effect of lean from high performance manufacturing (HPM) project perspective in relation to supply chain management

Historical perspective on the concept of health in ancient societies

La vejez es una etapa más del ser humano que ha sido interpretada de forma variable dependiendo del contexto social en el cual se analizara. A la hora de considerar la vejez en la sociedad del siglo XXI, se impone una reflexión sobre la misma a través del espacio y del tiempo, con el fin de entender este complejo fenómeno en la vida del ser humano en su totalidad, como un hecho ligado a la cultura y no sólo biológico.Ageing, one of the stages of human life, has been interpreted differently depending on the social context in which it has been analysed. The consideration of ageing in the 21st century demands a meditation about the concept through space and time, in order to understand wholly this complex phenomenon in human life, as a cultural not only biological fact

High performance and small footprint spot size converters based on SWG metamaterial lenses

Spot size converters with high expansion ratio are required in a variety of situations. This is the case of non-focusing Silicon on Insulator (SOI) fiber-to-chip grating couplers, which typically require long adiabatic tapers (Ltaper >100μm) from the narrow single-mode waveguides (WSi-wire ~ 500nm) to the wide grating region (Wgrating ~ 15μm). Here, we explore the potential of subwavelength grating (SWG) dielectric metamaterials to implement integrated GRaded INdex (GRIN) lenses to expand the mode field. Our designs achieve the desired Beam Expansion (BE) with insertion losses below 1dB over a distance of only LBE ~ 17μm.Ministerio de Economía y Competitividad, Programa Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad (cofinanciado FEDER), (TEC2016-80718-R); Universidad de Málaga. Ministerio de Educación, Cultura y Deporte (MECD) (FPU16/06121); Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

TRADUCIR A UN PREMIO NOBEL: BEIM HÄUTEN DER ZWIEBEL, DE GÜNTER GRASS

This paper will present the task of a literary translator of literary works that have internationalrecognition –such as the translation of Beim Häuten der Zwiebel written by the Nobel Prize GünterGrass– considering the basic concepts of editorial translation. But first of all, it will take into account the task of a literary translator. And from that point, it will deal with the practical view of the analysis of some passages of the German original novel and its equivalent in Spanish –translated by the well-known translator Miguel Sáenz. This analysis will be carried out since the field of editorial translation and set the main theoretical foundations of the subject of this study.El presente trabajo expondrá, desde los presupuestos propios de la traducción editorial, la labor del traductor literario de obras que tienen un reconocimiento internacional, como es el caso de la traducción de Beim Häuten der Zwiebel, del Premio Nobel Günter Grass. Para ello, tras analizar en una primera parte la labor del traductor literario, en un entorno propio de la traducción editorial, y establecer los principales fundamentos teóricos del objeto de estudio, se abordará el análisis, desde el punto de vista práctico, de la traducción de fragmentos de la obra original alemana, y su correspondencia española, llevado a cabo por el conocido traductor Miguel Sáenz

Patología oral y maxilofacial en la mujer maltratada

Objetivos: Analizar las características sociodemográficas de la víctima y del agresor en la violencia de género, así como los tipos de violencia, mecanismos de agresión y los tipos de lesiones maxilofaciales y del aparato estomatognático producto de la violencia en mujeres. Material y método: Revisión bibliográfica utilizando las bases de datos Pubmed y Google Académico. Resultados y conclusiones: La violencia de género se puede dar a cualquier edad y las mujeres pueden ser víctimas independientemente de su nivel de estudios y su etnia. En la mayoría de los casos, el agresor es la pareja actual de la mujer. La forma más común de violencia es el abuso físico, con elevada frecuencia de lesiones en la región maxilofacial siendo los traumatismos del tercio medio los más prevalentes. El complejo dentoalveolar es el más comúnmente afectado seguido por la órbita, el complejo cigomaticomaxilar, el hueso nasal y la mandíbula. En cuanto a la cavidad bucal, las fracturas de corona fueron las más comúnmente observadas, seguidas de avulsión y movilidad.Objectives: To analyze the socio-demographic characteristics of the victim and the aggressor in gender-based violence, as well as the types of violence, mechanisms of aggression and the types of maxillofacial and stomatognathic system injuries resulting from violence in women. Material and method: Literature review using Pubmed and Google Academic databases. Results and conclusions: Gender violence can appear at any age and women can be victims regardless of their level of education and ethnicity. In most cases, the aggressor is the woman’s current partner. The most common form of violence is physical abuse, with a high frequency of injuries in the maxillofacial region, the injuries of the middle third being the most prevalent. The dentoalveolar complex is most commonly affected followed by the orbital bone, the arch zygomatic, the nasal bone and the jaw. As for the oral cavity, crown fractures were the most commonly observed, followed by avulsion and mobility.Universidad de Sevilla. Grado en Odontologí

Overcoming function annotation errors in the Gram-positive pathogen Streptococcus suis by a proteomics-driven approach

Background: Annotation of protein-coding genes is a key step in sequencing projects. Protein functions are mainly assigned on the basis of the amino acid sequence alone by searching of homologous proteins. However, fully automated annotation processes often lead to wrong prediction of protein functions, and therefore time-intensive manual curation is often essential. Here we describe a fast and reliable way to correct function annotation in sequencing projects, focusing on surface proteomes. We use a proteomics approach, previously proven to be very powerful for identifying new vaccine candidates against Gram-positive pathogens. It consists of shaving the surface of intact cells with two proteases, the specific cleavage-site trypsin and the unspecific proteinase K, followed by LC/MS/MS analysis of the resulting peptides. The identified proteins are contrasted by computational analysis and their sequences are inspected to correct possible errors in function prediction. Results: When applied to the zoonotic pathogen Streptococcus suis, of which two strains have been recently sequenced and annotated, we identified a set of surface proteins without cytoplasmic contamination: all the proteins identified had exporting or retention signals towards the outside and/or the cell surface, and viability of protease-treated cells was not affected. The combination of both experimental evidences and computational methods allowed us to determine that two of these proteins are putative extracellular new adhesins that had been previously attributed a wrong cytoplasmic function. One of them is a putative component of the pilus of this bacterium. Conclusion: We illustrate the complementary nature of laboratory-based and computational methods to examine in concert the localization of a set of proteins in the cell, and demonstrate the utility of this proteomics-based strategy to experimentally correct function annotation errors in sequencing projects. This approach also contributes to provide strong experimental evidences that can be used to annotate those proteins for which a Gene Ontology (GO) term has not been assigned so far. Function annotation correction would then improve the identification of surfaceassociated proteins in bacterial pathogens, thus accelerating the discovery of new vaccines in infectious disease research

Tilted subwavelength gratings: controlling anisotropy in metamaterial nanophotonic waveguides

Subwavelength grating (SWG) structures are an essential tool in silicon photonics, enabling the synthesis of metamaterials with a controllable refractive index. Here we propose, for the first time to the best of our knowledge, tilting the grating elements to gain control over the anisotropy of the metamaterial. Rigorous finite difference time domain simulations demonstrate that a 45° tilt results in an effective index variation on the fundamental TE mode of 0.23 refractive index units, whereas the change in the TM mode is 20 times smaller. Our simulation predictions are corroborated by experimental results. We furthermore propose an accurate theoretical model for designing tilted SWG structures based on rotated uniaxial crystals that is functional over a wide wavelength range and for both the fundamental and higher order modes. The proposed control over anisotropy opens promising venues in polarization management devices and transformation optics in silicon photonics.Universidad de Málaga (UMA); Ministerio de Economía y Competitividad (MINECO) (IJCI-2016-30484, TEC2015-71127-C2-R, TEC2016-80718-R); Ministerio de Educación, Cultura y Deporte (MECD) (FPU16/06762); European Regional Development Fund (ERDF); Comunidad de Madrid (SINFOTON-CM S2013/MIT-2790); European Association of National Metrology Institutes (EURAMET) (H2020-MSCA-RISE-2015:SENSIBLE, JRP-i22 14IND13 Photind)

The role of progressive, therapeutic exercise in the management of upper limb tendinopathies: A systematic review and meta-analysis

Among upper limb tendinopathies, rotator cuff-related shoulder pain and lateral elbow tendinopathy are the most representative disorders. Therapeutic exercise arises as an effective approach, but there is no consensus about the optimal progression criteria. Objective: To compare progression criteria and effectiveness of isolated, progressive exercises in the management of upper limb tendinopathies. Additionally, to perform a meta-analysis of pain/function for the selected programs. Design: Systematic Review and Meta-Analysis. Method: Database search of randomized-controlled-trials including progressive exercise was conducted in PubMed and Scopus until October 2020. Meta-analysis’ inclusion criteria were: no data duplicity; 3-months follow-up; comparison between any type of progressive exercise program. Risk of bias was assessed with PEDro score, and level of evidence followed GRADE guidelines. Effect size was calculated with Cohen’s d. Results: Eleven studies were included. GRADE revealed low-quality evidence for meta-analysis of pain during activity (d = 0.29) and function (d = 0.33) at 3 months. Progression criteria were categorised into two divisions, being pain the central concept. Pain (rest/activity/night) and function improved significantly within-group, but between-group changes were heterogeneous. Meta-analysis regarding pain showed good homogeneity with significant, moderate effects (I2 = 20%; p = 0.005; mean d = 0.29); function yielded important heterogeneity with non-significant, moderate effects (I2 = 81%; p = 0.17; mean d = 0.33). Conclusions: Pain was the most frequent benchmark when modulating and progressing the exercises, although other criteria were found such as fatigue or self-perceived ability. Progressive exercise seems effective to manage upper limb tendinopathies, but the superiority of a progression criterion against others remains unclear. (...)This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Funding for open access charge: Universidad de Málag

Designing anisotropy with waveguide subwavelength structures

Silicon sub-wavelength structures have become a versatile design tool for practical, high-performance integrated optical devices, ranging from highly efficient grating couplers to ultra-broadband beam-splitters. Recently, some of the basic anisotropic properties of these structures have been proposed for advance device design. Here we explore these properties in detail, from the underlying physics to emerging applications in on-chip polarization management.Ministerio de Economía y Competitividad, Programa Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad (cofinanciado FEDER), Proyectos TEC2016-80718-R, TEC2015-71127-C2-1-R (FPI scholarship BES-2016-077798), and IJCI-2016-30484, the Community of Madrid (S2013/MIT-2790), the Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech, the EMPIR program (JRP-i22 14IND13 Photind), co-financed by the participating countries and the European Union’s 2020 research and innovation program, and the Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant No. 734331

Designing polarization management devices by tilting subwavelength grating structures

Subwavelength gratings (SWG) are periodic structures which behave as controllable homogeneous metamaterials. SWGs are extremely interesting when they are used in platforms with a limited choice of material refractive indices, enabling the design of a myriad of high-performance devices. Here we present a novel technique to gain control over the intrinsic anisotropy of the synthesized metamaterial. We show that tilting the silicon segments in a SWG structure mainly affects the in-plane (TE) modes, with little impact on the out-of-plane (TM) modes. Moreover, we present a methodology to quickly but accurately calculate the modes of a tilted periodic structure modeling the structure as a rotated uniaxial crystal which can be solved with an anisotropic mode solver. Measurements on a set of fabricated tilted SWG waveguides validate our simulation results. By using the presented technique, we design a polarization beam splitter based on a 2x2 multimode interferometer. The design is based on the optimization of the tilting angle to tone the beat length of the TE modes to be a half of the beat length of the TM modes.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech; Ministerio de Economía y Competitividad (MINECO) (IJCI-2016-30484, TEC2015-71127-C2-R, TEC2016-80718-R); Ministerio de Educación, Cultura y Deporte (MECD) (FPU16/06762); European Regional Development Fund (ERDF); Comunidad de Madrid (SINFOTON-CM S2013/MIT-2790); European Association of National Metrology Institutes (EURAMET) (H2020-MSCA-RISE-2015:SENSIBLE, JRP-i22 14IND13 Photind)