Az MTA Könyvtár és Információs Központ gyűjteménye a WorldCat nemzetközi katalógusban = The collection of the Library and Information Centre of Hungarian Academy of Science in the international WorldCat catalogue

The Library and Information Centre of HAS (MTA KIK) joined to the international WorldCat catalogue in February 2017. Currently MTA KIK is the only active WorldCat member from Hungary, although a lot of Hungarian libraries are planning to join. MTA KIK submitted more than 770.000 records (about 76% of its online catalogue) to the WorldCat international catalogue in November 2017, after almost 1 year preparatory phase. This study is about the contracting with OCLC and we describe the workflow of the preparation and the record-export

Fractional anisotropy shows differential reduction in frontal-subcortical fiber bundles - A longitudinal MRI study of 76 middle-aged and older adults

Motivated by the frontal- and white matter (WM) retrogenesis hypotheses and the assumptions that fronto-striatal circuits are especially vulnerable in normal aging, the goal of the present study was to identify fiber bundles connecting subcortical nuclei and frontal areas and obtain site-specific information about age related fractional anisotropy (FA) changes. Multimodal magnetic resonance image acquisitions [3D T1-weighted and diffusion weighted imaging (DWI)] were obtained from healthy older adults (N = 76, range 49–80 years at inclusion) at two time points, 3 years apart. A subset of the participants (N = 24) was included at a third time-point. In addition to the frontal-subcortical fibers, the anterior callosal fiber (ACF) and the corticospinal tract (CST) was investigated by its mean FA together with tract parameterization analysis. Our results demonstrated fronto-striatal structural connectivity decline (reduced FA) in normal aging with substantial inter-individual differences. The tract parameterization analysis showed that the along tract FA profiles were characterized by piece-wise differential changes along their extension rather than being uniformly affected. To the best of our knowledge, this is the first longitudinal study detecting age-related changes in frontal-subcortical WM connections in normal aging.publishedVersio