Steroidal anti inflammatory drug betamethasone significantly alters level of striatal dopamine in a rat model of Parkinson’s disease

Many scientific efforts have been well done to investigate the effects of anti inflammatory agents on the degenerative brain diseases such as Parkinson’s (PD) or Alzheimer’s disease and their affiliated sings. Previously we showed the effectiveness of steroids on rigidity of PD and in the study for further mechanistic investigation of that observation the microdialysis technique was employed to determine the striatal dopamine changes in parkinsonian rats after administration of betamethasone (0.12, 0.24 mg/kg) respectively. Our findings showed us the significant increase in the striatal dopaminergic neurotransmission (P<0.05) after administration of betamethasone comparing to the controls. These observations suggest a new mechanism for betamethasone on striatum dopaminergic neurotransmission leading us to gather further evidence about effectiveness of betamethasone in PD

Investigating the relationship between resources and expenditures of Agricultural Bank and its effect on national production and Iranian Capital and Labor Support in Agriculture

This research investigates the relationship between resources and expenditures of Agricultural Bank and its effect on national production and Iranian Capital and Labor Support during 2007-2011. The statistical population of the research is Central Agricultural Bank of Iran; therefore, the sample in this research is equal to the population. It is a descriptive correlation research with a practical goal. In order to rest hypotheses, the researcher has used regression method to assess the effect of credit facilities on National Production in agriculture. Moreover, the effect of attracting banking sources on paying facilities was examined too. Before testing the hypotheses, the researcher administered Kolmogorov – Smirnov test to make sure if the data were normally distributed. The results of testing hypotheses showed that there was no relationship between paying the facilities in agronomy and gardening and National Production in this sector. There was a direct relationship between paying facilities in livestock and poultry and National Production in this sector. There was a direct relationship between paying facilities in fisheries and aquaculture and National Production in this sector. Finally, there was a direct relationship between attracting banking sources and paying facilities

Money laundering and its effect on social and political economy in Iran

Today, using the most appropriate financial combination for preventing manipulation of influence and pressure on the structure of the country is one of the most important concerns of every country’s cultural-financial policy so that social, political, and financial segments are greatly impressed in all aspects. In this regard, there are many destructive factors which destroy the balance. Money laundering, according to global statistics and facts, could be one of the most destructive one. Money laundering is done through many different ways which leads to the corruption of authorities and financial instability and banking volatility and also reduction of productivity and government’s control over economic policies. Step-by-step control and assessment of financial institutions and enterprises and all organizations which somehow affect the flow of money laundering is really difficult and to achieve predetermined goals, highly secure solutions and also development of appropriate culture in society for preventing the flow of money laundering are necessary

Money laundering and its effect on social and political economy in Iran

Today, using the most appropriate financial combination for preventing manipulation of influence and pressure on the structure of the country is one of the most important concerns of every country’s cultural-financial policy so that social, political, and financial segments are greatly impressed in all aspects. In this regard, there are many destructive factors which destroy the balance. Money laundering, according to global statistics and facts, could be one of the most destructive one. Money laundering is done through many different ways which leads to the corruption of authorities and financial instability and banking volatility and also reduction of productivity and government’s control over economic policies. Step-by-step control and assessment of financial institutions and enterprises and all organizations which somehow affect the flow of money laundering is really difficult and to achieve predetermined goals, highly secure solutions and also development of appropriate culture in society for preventing the flow of money laundering are necessary

The Possibilities and Characteristics of the Necessary Transcendental Knowledge from the Perspective of Mulla Sadra

One of the most important topics in the view of the great philosophers is the question of the possibility and characteristics of the necessary transcendental knowledge. As one of the leading philosophers and the founder of transcendental wisdom, Mulla Sadra has argued and argued. This article aims to analyze Sadra's views on the possibility and characteristics of the necessary transcendental knowledge with an analytical approach. Examination of Sadra's views in this regard indicates that formal knowledge and Acquired Knowledge, in essence, God is impossible. But if the oneness of the uniqueness of knowledge is one can attain the right of transcendental as much as one's being is capable of, and this ontology can only be accomplished have the negative of the material and attains the highest degree of knowledge, that's mean, death

Evaluation studies of robotic rollators by the user perspective: A systematic review

Background: Robotic rollators enhance the basic functions of established devices by technically advanced physical, cognitive, or sensory support to increase autonomy in persons with severe impairment. In the evaluation of such Ambient Assisted Living solutions, both the technical and user perspectives are important to prove usability, effectiveness, and safety, and to ensure adequate device application.Objective: The aim of this systematic review is to summarize the methodology of studies evaluating robotic rollators with focus on the user perspective and to give recommendations for future evaluation studies.Methods: A systematic literature search up to December 31, 2014 was conducted based on the Cochrane Review methodology using the electronic databases PubMed and IEEE Xplore. Articles were selected according to the following inclusion criteria: Evaluation studies of robotic rollators documenting human-robot interaction, no case reports, published in English language.Results: Twenty-eight studies were identified that met the predefined inclusion criteria. Large heterogeneity in the definitions of the target user group, study populations, study designs, and assessment methods was found across the included studies. No generic methodology to evaluate robotic rollators could be identified. We found major methodological shortcomings related to insufficient sample descriptions and sample sizes, and lack of appropriate, standardized and validated assessment methods. Long-term use in habitual environment was also not evaluated.Conclusions: Apart from the heterogeneity, methodological deficits in most of the identified studies became apparent. Recommendations for future evaluation studies include: clear definition of target user group, adequate selection of subjects, inclusion of other assistive mobility devices for comparison, evaluation of the habitual use of advanced prototypes, adequate assessment strategy with established, standardized and validated methods, and statistical analysis of study results. Assessment strategies may additionally focus on specific functionalities of the robotic rollators allowing an individually tailored assessment of innovative features to document their added value

Investigating the effects of heavy metals in the waste leachate on the groundwater quality near the landfill (case study: Landfill of Saravan, Rasht)

The main and fundamental scientific reason of scientific community attention to the issue of leachate pollution and its treatment is the possible danger of contamination of water, soil and to some extent air. The reason is that the leachate of landfill in fact is acomplex waste withhigh pollution. Today, in our country, especially in northern areas due to high groundwater levels, the problem of waste disposal and the effects of their leachate entering alluvial groundwater and aquifer contamination downstream based on hydrodynamic thickness in the movement of water is highly regarded andentering a considerable amount of pollution (nitrates, heavy metals, etc.) to underground water sources used for drinking and agriculture, in the long term become a social problem. Saravan landfill is located on 15 km road Rasht of to Tehran is like a black spot in the in the green Hyrcanian forest and receives more than 500 tons of waste daily from provinces cities,particularly Rasht which with no environmental assessment for selected waste disposal, waste disposal is inadequate in Saravan and because of evaporation, fermentation and decomposition of the waste and leachate percolation into the soil and water resources it is associated with high pollution and unleashed leachate river in the heart of nature and based on the ranking of Index criteria it is unacceptable. In this study, sampling was conducted in 2 upstream wells, 3 downstream wells of Saravan landfill then the samples were analyzed by atomic absorption.  The results indicate the presence of heavy metals (chromium - lead – zinc -iron - manganese) in water of downstream wells of the landfill compared to upstream wells and the control wells or in other words, it was significantly more than the control and upstream wells and the average concentrations of Pb, Cr, MN, Fe higher than drinking water standards and the mean concentration of MN and Cr in the research water wells was more than standard water for irrigation and agricultural. It shows the leachate percolation into soil and ground water that has been polluted the nearby water of the landfill.Keywords: Groundwater, Landfill, Leachate, Heavy Metals, Sarava