49 research outputs found

    Politics, Power and Agency in Early Childhood Care Education In Nigeria

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    Politics, power and agency are very important aspect of early childhood care educational management practices in Nigeria in the sense that education is an off-shoot of the political system indulged with power and agency to promote the development of ECCE. Politics fashions education and education modifies politics, powers are imposed on stakeholders of education for proper monitoring and execution of ECCE projects. This paper examines the concepts of politics, power and agency in early childhood care education and the relationship between politics, power and agency and education in Nigeria. Keywords: Politics, Power, Agency, Early Childhood Care, Education DOI: 10.7176/JEP/10-10-14 Publication date: April 30th 2019

    Counselling for Security, Creativity and Learning in Early Childhood Education

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    The paper examines counselling for security, creativity and learning in early childhood education. Primary data was collected through validated instrument of questionnaire administration. Stratified random sampling was used for sample selection to elicit information from 285 respondents who were counsellors from six Local Governments Areas in Akwa Ibom State. Logistic regression was used for data analysis. The result revealed that counselling for security had a significant effect on learning in early childhood education. Also, creativity has a significant effect on learning in early childhood education. The paper suggests that counsellors should integrate developmental and preventive strategies that are comprehensive in counselling children to act in a proactive and goal oriented manner. Keywords: Early Childhood Education, Counselling DOI: 10.7176/JEP/10-11-13 Publication date: April 30th 201

    Research background, approach, and methodologies for ensuring safety, integrity, and value optimization in the global biopharmaceutical supply chain

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    Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management, 2009.Includes bibliographical references (leaves 52-58).As the biomanufacturing (BioMAN) initiative within the MIT Center for Biomedical Innovation enters its third year of active research, the competitive landscape and sources of resources to support biomanufacturing research have rapidly changed. This research is an attempt to provide insight into the following primary questions: **What research strategies could BioMAN effectively employ moving forward? **What is a specific example of BioMAN research targeted towards new potential resource sources? **What are the details of the research approach for a project that would be of interest to both existing and new resource sources? By leveraging a competitive analysis framework, a recommendation was developed for BioMAN to pursue the market segment of system-based research-centric programs without offering training or custom projects. Specific potential resource sources and collaboration partners were identified towards meeting this target market. An example interdisciplinary research program proposal was constructed with the intent to submit to the Alfred P. Sloan Foundation. Additionally, the details of planned approach to a project focused on biomanufacture location decisions were developed towards attracting support from both industrial partners and non-profit foundations.by Reuben Dumont Domike.M.B.A

    Pharmaceutical powders in experiment and simulation : towards a fundamental understanding

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    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, September 2004.Includes bibliographical references.(cont.) The DEM simulation was used to simulate the relative importance of cohesion and friction. For angle of repose simulations, increasing the cohesion increased the final angle in a consistent, linear fashion. Increasing the interparticle friction coefficient increased the final angle up to a critical friction coefficient. For the range of two dimensional simulations with the particles shaped as discs, this critical friction coefficient was about 0.30. Above this threshold, increasing the interparticle friction had no impact on the angle of repose. This suggests that for most pharmaceutical powders, the cohesion and shape are the most important particle properties. Case studies relating interparticle adhesion to labscale powder performance (flow and blends) were completed with two active pharmaceutical ingredients and a number of excipients. In all of the flow cases, the rank order of interparticle or intermaterial adhesion forces measured with AFM was exactly predictive of the rank order of ease of flow. Similarly, in all of the blending case studies, the rank order of adhesion force between the active pharmaceutical ingredient and the excipient was exactly predictive of the rank order stability of blends of the materials. The blend stability was quantified using an on-line, nondestructive, noninvasive light induced fluorescence (LIF) instrument. Separately, the LIF instrument was used to estimate the content of fluorescent drugs (caffeine and triamterene) in tablets by measuring the surface fluorescence. A theoretical description of the accuracy of the surface measurement to correctly estimate the total content in a tablet ...The flow of fine powder has not been fully understood nor has it been predictable by current simulation techniques. With the use of atomic force microscopy (AFM), interparticle forces of attraction and interparticle friction forces between fine particles have been measured with unprecedented success. In a novel coupling of technologies, the microscopic interparticle force data was used in a discrete element model (DEM) simulation to predict the bulk powder flow in multiple geometries. Excellent agreement between the simulated angles of repose for both glass beads and a microcrystalline cellulose pharmaceutical excipient was obtained. Qualitative agreement between simulation and experiment of flow in a rotating box was also obtained for these materials. The ability to measure interparticle friction forces for non-spherical particles was a novel development. The presence of surface asperities was shown to be directly responsible for changes in friction force. Interparticle friction coefficients were established by varying the applied load between particles. The average interparticle friction between the cellulose particles was 0.44, double the value for glass beads. For both particle types, the population of measured friction coefficients was well represented by a normal distribution. Interparticle friction was also measured between lactose particles. However, the surfaces of the lactose particles smoothed under high applied loads and the measured friction coefficients were lower (an average value of 0.26) than the cellulose particles. The similar friction coefficients for glass beads and smooth lactose particles further suggest that the interparticle friction was strongly dependent upon the surface asperities.by Reuben Dumont Domike.Ph.D

    The impact of improved materials in poly(vinyl chloride)-based endotracheal tubes

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    Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2004.Includes bibliographical references.Endotracheal tubes (ETs) are used to aid artificial ventilation in millions of medical patients every year and are known to invoke the proliferative phase in the cell linings. The technical objective of this work was to investigate in vitro the interaction between epithelial cells and current poly(vinyl chloride)-based ET materials, as well as some ET samples embedded with materials intended to improve biocompatibility properties of the tubes. Cells were grown in wells with small samples of ETs and proliferation and migration were observed using phase microscopy. ETs appeared to increase cell growth wherever cells came into contact with the material. The cell morphology altered once in contact with the ET sample. Cell growth on and around the ETs with embedded material appeared to slow, but had significant visible changes in cell morphology. The need for continued research in this area of research and development and future steps are addressed. A proposal for starting a company around a safer material for use in endotracheal tubes was developed and showed significant barriers to entry for a small medical device company with a single product. Subsequently, the most appropriate approach for bringing a new ET to the market would be by way of a licensing with an existing manufacturer.by Kristin Rebecca Domike.M.Eng

    A review of current techniques for the evaluation of powder mixing

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    Blending a mixture of powders to a homogeneous system is a crucial step in many manufacturing processes. To achieve a high quality of the end product, powder mixtures should be made with high content uniformity. For instance, producing uniform tablets depends on the homogeneous dispersion of active pharmaceutical ingredient (API), often in low level quantities, into excipients. To control the uniformity of a powder mixture, the first required step is to estimate the powder content information during blending. There are several powder homogeneity evaluation techniques which differ in accuracy, fundamental basis, cost and operating conditions. In this article, emerging techniques for the analysis of powder content and powder blend uniformity, are explained and compared. The advantages and drawbacks of all the techniques are reviewed to help the readers to select the appropriate equipment for the powder mixing evaluation. In addition, the paper highlights the recent innovative on-line measurement techniques used for the non-invasive evaluation of the mixing performance

    The Critique of the Implementation of Early Childhood Education in Cross River State – Nigeria

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    is a truism that the importance and value of education in the early years of life have been acknowledged for more than 2000 years ago. Relatively, recent factors have brought early childhood education to the forefront of public awareness. Fundamental changes in the economy, family life, public awareness, and public support have had a profound effect on early childhood education. How we approach the education and care of young children depends, to a great extent, on what we believe children are like. Programmes for preschoolers are often structured around some underlying assumptions about the nature of children. Undoubtedly, the implementation of the early Childhood Education in Cross River State as stipulated in the National Policy on Education has been marred with certain implementation problems ranging from lack of infrastructural facilities, prohibitive cost and commercialization, lack of qualified staff, overcrowded classrooms, lack of supervision, neglect of mother tongue amongst others. This paper therefore, takes a cursory look at the critique of the implementation of Early Childhood Education in Cross River State and the way forward

    The Recombinant History Apparatus Presents: Terminal Time

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    Replication Data for: Gender Stereotypes, Political Leadership, and Voting Behavior in Tunisia

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    Replication data for: Gender Stereotypes, Political Leadership, and Voting Behavior in Tunisia
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