Improving Reliability and Availability of IaaS Services in Hybrid Clouds

This paper investigates into IaaS service provisioning in hybrid cloud which comprises private and public clouds. It proposes a hybrid cloud framework in order to improve reliability and availability of IaaS services by taking into account alternative services which are available through public clouds. However, provisioning of alternative services in hybrid cloud involves complex processing, intelligent decision making and reliability and consistency issues. In the proposed framework, we develop an agent-based system using cloud ontology in order to identify and rank alternative cloud services which users can acquire in the event of failures or unavailability of desired services. The proposed framework also exploits transactional techniques in order to ensure the reliability and consistency of the service acquisition process. The proposed framework is evaluated through various experiments which show that it improves service availability and reliability in hybrid cloud

Statistical analysis of patients with Crohn desease

Import 05/08/2014Tato práce zpracovává medicínská data pacientů s Crohnovou nemocí poskytnutá Fakultní nemocnicí v Ostravě (FNO). Jejím hlavním cílem je vytvoření vhodného uživatelského rozhraní, s jehož pomocí je možno provádět podrobné explorační analýzy dat pacientů i analyzovat závislosti mezi vybranými veličinami a genetickými faktory.This work processes medical data of patients with Crohn's desease which are provided by University Hospital of Ostrava (UHO). The main objective of this work is to create a suitable user interface through which is going to be possible to implement detailed exploratory analysis of patient's data and to analyse dependencies between selected variables and genetic factors.470 - Katedra aplikované matematikyvýborn

Potassium trifluoro­[(Z)-3-(oxan-2-yl­oxy)prop-1-en-1-yl]borate monohydrate

The title compound, K+·C8H13BF3O2 −·H2O, which was obtained from the reaction of a modified form of Z-vinylic telluride via a transmetalation reaction with n-BuLi, crystallizes as K+ and C8H13BF3O2 − ions along with a water mol­ecule. The K+ cation is surrounded by four anions, making close contacts with six F atoms at 2.659 (3)–2.906 (3) Å and with two O atoms at 2.806 (3) and 2.921 (3) Å in a distorted bicapped trigonal-prismatic geometry

Natalizumab treatment shows low cumulative probabilities of confirmed disability worsening to EDSS milestones in the long-term setting.

Abstract Background Though the Expanded Disability Status Scale (EDSS) is commonly used to assess disability level in relapsing-remitting multiple sclerosis (RRMS), the criteria defining disability progression are used for patients with a wide range of baseline levels of disability in relatively short-term trials. As a result, not all EDSS changes carry the same weight in terms of future disability, and treatment benefits such as decreased risk of reaching particular disability milestones may not be reliably captured. The objectives of this analysis are to assess the probability of confirmed disability worsening to specific EDSS milestones (i.e., EDSS scores ≥3.0, ≥4.0, or ≥6.0) at 288 weeks in the Tysabri Observational Program (TOP) and to examine the impact of relapses occurring during natalizumab therapy in TOP patients who had received natalizumab for ≥24 months. Methods TOP is an ongoing, open-label, observational, prospective study of patients with RRMS in clinical practice. Enrolled patients were naive to natalizumab at treatment initiation or had received ≤3 doses at the time of enrollment. Intravenous natalizumab (300 mg) infusions were given every 4 weeks, and the EDSS was assessed at baseline and every 24 weeks during treatment. Results Of the 4161 patients enrolled in TOP with follow-up of at least 24 months, 3253 patients with available baseline EDSS scores had continued natalizumab treatment and 908 had discontinued (5.4% due to a reported lack of efficacy and 16.4% for other reasons) at the 24-month time point. Those who discontinued due to lack of efficacy had higher baseline EDSS scores (median 4.5 vs. 3.5), higher on-treatment relapse rates (0.82 vs. 0.23), and higher cumulative probabilities of EDSS worsening (16% vs. 9%) at 24 months than those completing therapy. Among 24-month completers, after approximately 5.5 years of natalizumab treatment, the cumulative probabilities of confirmed EDSS worsening by 1.0 and 2.0 points were 18.5% and 7.9%, respectively (24-week confirmation), and 13.5% and 5.3%, respectively (48-week confirmation). The risks of 24- and 48-week confirmed EDSS worsening were significantly higher in patients with on-treatment relapses than in those without relapses. An analysis of time to specific EDSS milestones showed that the probabilities of 48-week confirmed transition from EDSS scores of 0.0–2.0 to ≥3.0, 2.0–3.0 to ≥4.0, and 4.0–5.0 to ≥6.0 at week 288 in TOP were 11.1%, 11.8%, and 9.5%, respectively, with lower probabilities observed among patients without on-treatment relapses (8.1%, 8.4%, and 5.7%, respectively). Conclusions In TOP patients with a median (range) baseline EDSS score of 3.5 (0.0–9.5) who completed 24 months of natalizumab treatment, the rate of 48-week confirmed disability worsening events was below 15%; after approximately 5.5 years of natalizumab treatment, 86.5% and 94.7% of patients did not have EDSS score increases of ≥1.0 or ≥2.0 points, respectively. The presence of relapses was associated with higher rates of overall disability worsening. These results were confirmed by assessing transition to EDSS milestones. Lower rates of overall 48-week confirmed EDSS worsening and of transitioning from EDSS score 4.0–5.0 to ≥6.0 in the absence of relapses suggest that relapses remain a significant driver of disability worsening and that on-treatment relapses in natalizumab-treated patients are of prognostic importance

PENGARUH PERSEPSI KEADILAN PEMULIHAN LAYANAN TERHADAP LOYALITAS DAN GETOK TULAR KONSUMEN

Penelitian ini bertujuan untuk menganalisis pengaruh pengaruh persepsi keadilan pemulihan layanan terhadap loyalitas dan getok tular konsumen. Responden pada penelitian ini adalah konsumen yang mengalami kegagalan layanan dan mendapatkan pemulihan layanan. Metode yang digunakan untuk pengambilan sampel dalam penelitian ini adalah purposive sampling. Pengumpulan data dalam penelitian ini dilakukan dengan menyebarkan kuesioner sejumlah 270 eksemplar kepada para responden. Penelitian ini menggunakan alat analisis deskriptif statistik, analisis regresi berganda, serta analisis regresi sederhana dengan bantuan program SPSS versi 16.0. Hasil penelitian menunjukkan bahwa persepsi keadilan (keadilan distributif, keadilan prosedural dan keadilan interaksional) secara bersama – sama mempengaruhi kepuasan. Kepuasan konsumen kemudian akan meningkatkan loyalitas dan penyebaran getok tular positif

PROXY TO PARTICIPATION AT THE GENERAL MEETING OF SHAREHOLDERS IN PUBLIC JOINT- STOCK COMPANIES

Niniejsza praca stanowi analizę instytucji pełnomocnictwa do udziału w walnym zgromadzeniu w spółkach akcyjnych publicznych. Punktem wyjścia do rozważań jest rozpatrzenie przyczyn, dla których została przyjęta Dyrektywa 2007/36/WE Parlamentu Europejskiego i Rady z dnia 11 lipca 2007 r. w sprawie wykonywania niektórych praw akcjonariuszy spółek notowanych na rynku regulowanym. W pracy zostały omówione przepisy zmienione i dodane nowelizacją Kodeksu spółek handlowych z 5.12.2008 r. Przede wszystkim jednak dokonano analizy poszczególnych elementów stosunku pełnomocnictwa, tj. zakresu podmiotowego i przedmiotowego oraz formy, w jakiej może zostać udzielone. Ostatni rozdział został poświęcony zagadnieniu charakteru prawnego pełnomocnictwa do udziału w walnym zgromadzeniu i stanowi próbę odpowiedzi na pytanie o jego tożsamość z pełnomocnictwem unormowanym przepisami Kodeksu cywilnego.This paper is an analysis of the institution of proxy to participation at the general meeting of shareholders. The starting point is consideration the goals of Directive 2007/36/EC of the European Parliament and the Council of 11 July 2007 on the exercise of certain rights of shareholders in listed companies. Moreover it considers rules of the Code of Commercial Companies which are related to the subject of proxy to participation at the general meeting of shareholders. Above all, it is the analysis of the scope of subject and object and the form in which it can be granted.The last chapter is devoted to the issue of the legal nature of the power of attorney to participate in the general meeting and an attempt to answer the question about its legal identity

PENGARUH PERSEPSI KEADILAN PEMULIHAN LAYANAN TERHADAP LOYALITAS DAN GETOK TULAR KONSUMEN

Penelitian ini bertujuan untuk menganalisis pengaruh pengaruh persepsi keadilan pemulihan layanan terhadap loyalitas dan getok tular konsumen. Responden pada penelitian ini adalah konsumen yang mengalami kegagalan layanan dan mendapatkan pemulihan layanan. Metode yang digunakan untuk pengambilan sampel dalam penelitian ini adalah purposive sampling. Pengumpulan data dalam penelitian ini dilakukan dengan menyebarkan kuesioner sejumlah 270 eksemplar kepada para responden. Penelitian ini menggunakan alat analisis deskriptif statistik, analisis regresi berganda, serta analisis regresi sederhana dengan bantuan program SPSS versi 16.0. Hasil penelitian menunjukkan bahwa persepsi keadilan (keadilan distributif, keadilan prosedural dan keadilan interaksional) secara bersama – sama mempengaruhi kepuasan. Kepuasan konsumen kemudian akan meningkatkan loyalitas dan penyebaran getok tular positif

XRF Imaging (MA-XRF) as a Valuable Method in the Analysis of Nonhomogeneous Structures of Grisaille Paint Layers

Stained glass paint layers made with vitreous paints can be a challenging subject for analyses. Their heterogenic structure requires proper experimental methodology in order to obtain valuable data. The main goal of this paper is to present the advantages of macro-XRF scanning (MA-XRF) in the non-destructive investigation of historical grisaille paint layers on the basis of research conducted on seven stained glass panels from the Dominican Monastery in Kraków, the Diocesan Museum in Kielce and the National Museum in Poznań (Poland). The obtained results showed the capabilities of MA-XRF scanning in technology recognition, the legibility of damaged fragments of painted depictions, as well as with distinguishing the elemental composition between vitreous paints in different colours. Additionally, SEM-EDS measurements are presented so as to acquire quantitative results and additional information concerning light elements