158 research outputs found
Eficácia dos exercÃcios de Cawthorne e Cooksey na melhoria do equilÃbrio e na prevenção de quedas em pessoas idosas: revisão da literatura
Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciado em FisioterapiaObjetivo: Analisar os resultados de ensaios clÃnicos sobre o protocolo de Cawthorne e Cooksey na melhoria do equilÃbrio em indivÃduos idosos. Metodologia: Pesquisa computorizada nas bases de dados: DOAJ (Directory of Open Access Journals); EBSCO; LILACS;PEDro; PubMed/Medline; SCIelo; ScienceDirect; ISI Web of Knowledge a fim de pesquisar estudos randomizados controlados. Foram selecionados artigos em lÃngua inglesa e portuguesa. A análise dos estudos foi feita por meio de revisão crÃtica dos conteúdos. Resultado: foram incluÃdos 5 estudos randomizados controlados envolvendo 201 participantes. Conclusão: O protocolo de Cawthorne e Cooksey permite novos padrões de estimulação vestibular e esta intervenção seria capaz de promover melhoras nas reações de equilÃbrio bem como na melhoria da autoconfiança e assim na prevenção de quedas.Objective: To analyze the results of different Clinical Trials concerning the efficacy of the Cawthorne and Cooksey exercise protocol in improving balance in elderly individuals. Methodology: A computerized search was conducted in the following databases: DOAJ (Directory of Open Access Journals); EBSCO; LILACS;PEDro; PubMed/Medline; SCIelo; ScienceDirect; ISI Web of Knowledge; with the intent of finding Randomized controlled trials. English and Portuguese written articles were selected. The analysis was made by critical revision of contents. Results: 5 randomized clinical trials were included, totaling 201 participants overall. Conclusion: The Cawthorne and Cooksey exercise protocol allows new patterns of vestibular stimulation, allowing this intervention to promote improvements in balance, as well as improvements in self-confidence and fall prevention.N/
Chapter Large Scale Capacitive Skin for Robots
Communications engineering / telecommunication
Eficácia dos exercÃcios de Cawthorne e Cooksey na melhoria do equilÃbrio e na prevenção de quedas em pessoas idosas: revisão da literatura
Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciado em FisioterapiaObjetivo: Analisar os resultados de ensaios clÃnicos sobre o protocolo de Cawthorne e Cooksey na melhoria do equilÃbrio em indivÃduos idosos. Metodologia: Pesquisa computorizada nas bases de dados: DOAJ (Directory of Open Access Journals); EBSCO; LILACS;PEDro; PubMed/Medline; SCIelo; ScienceDirect; ISI Web of Knowledge a fim de pesquisar estudos randomizados controlados. Foram selecionados artigos em lÃngua inglesa e portuguesa. A análise dos estudos foi feita por meio de revisão crÃtica dos conteúdos. Resultado: foram incluÃdos 5 estudos randomizados controlados envolvendo 201 participantes. Conclusão: O protocolo de Cawthorne e Cooksey permite novos padrões de estimulação vestibular e esta intervenção seria capaz de promover melhoras nas reações de equilÃbrio bem como na melhoria da autoconfiança e assim na prevenção de quedas.Objective: To analyze the results of different Clinical Trials concerning the efficacy of the Cawthorne and Cooksey exercise protocol in improving balance in elderly individuals. Methodology: A computerized search was conducted in the following databases: DOAJ (Directory of Open Access Journals); EBSCO; LILACS;PEDro; PubMed/Medline; SCIelo; ScienceDirect; ISI Web of Knowledge; with the intent of finding Randomized controlled trials. English and Portuguese written articles were selected. The analysis was made by critical revision of contents. Results: 5 randomized clinical trials were included, totaling 201 participants overall. Conclusion: The Cawthorne and Cooksey exercise protocol allows new patterns of vestibular stimulation, allowing this intervention to promote improvements in balance, as well as improvements in self-confidence and fall prevention.N/
Large Scale Capacitive Skin for Robots
Communications engineering / telecommunication
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Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis.
Liver X receptors (LXRs) are transcriptional regulators of cellular and systemic cholesterol homeostasis. Under conditions of excess cholesterol, LXR activation induces the expression of several genes involved in cholesterol efflux, facilitates cholesterol esterification by promoting fatty acid synthesis, and inhibits cholesterol uptake by the low-density lipoprotein receptor. The fact that sterol content is maintained in a narrow range in most cell types and in the organism as a whole suggests that extensive crosstalk between regulatory pathways must exist. However, the molecular mechanisms that integrate LXRs with other lipid metabolic pathways are incompletely understood. Here we show that ligand activation of LXRs in mouse liver not only promotes cholesterol efflux, but also simultaneously inhibits cholesterol biosynthesis. We further identify the long non-coding RNA LeXis as a mediator of this effect. Hepatic LeXis expression is robustly induced in response to a Western diet (high in fat and cholesterol) or to pharmacological LXR activation. Raising or lowering LeXis levels in the liver affects the expression of genes involved in cholesterol biosynthesis and alters the cholesterol levels in the liver and plasma. LeXis interacts with and affects the DNA interactions of RALY, a heterogeneous ribonucleoprotein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the mouse liver. These findings outline a regulatory role for a non-coding RNA in lipid metabolism and advance our understanding of the mechanisms that coordinate sterol homeostasis
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