256 research outputs found

    Promoting Stakeholder Participation in a Learning-Based Monitoring and Evaluation Framework

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    This research analysed monitoring and evaluation activities based on the Outcome Mapping methodology within the Zimbabwe Secondary Teacher Training Environmental Education Project (St2eep), an education for sustainability initiative in Zimbabwe. The majority of donorfunded environmental education programmes use conventional monitoring and evaluation approaches based on the logical frameworks (logframe) that guide the programme designs and management. Although research indicates significant problems with the implementation of these approaches, there are only a few documented examples of experiences with alternative monitoring and evaluation frameworks. The case of St2eep allowed us to compare three years of experiences with monitoring and evaluation based on the logframe, with two years of monitoring and evaluation based on Outcome Mapping. We evaluate how the project team and the donor organisation, VVOB (the Flemish Office for Development, Cooperation and Technical Assistance), have perceived the performance of Outcome Mapping with regards to the two main aims of monitoring and evaluation activities: accountability and learning. This is complemented with an analysis of monitoring documentation. The project team refers to the collaborative nature of monitoring and evaluation in St2eep, the principles of self-assessment and peer-assessment, combined with public recognition for project successes, as the key factors supporting learning and accountability through monitoring and evaluation in St2eep. The Outcome Mapping-based monitoring and evaluation system is shown to enhance ownership and participation of local stakeholders in the project’s monitoring and evaluation system

    The Relationship between Maternal Overprotection, Adolescent Internalizing and Externalizing Problems, and Psychological Need Frustration: A Multi-Informant Study Using Response Surface Analysis

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    Parents and adolescents may hold discrepant views about parents’ behaviors, which may be related to adolescent maladjustment. The goal of the present investigation was to examine associations between overprotective parenting and adolescents’ internalizing and externalizing problems and the frustration of their psychological needs (for autonomy, relatedness and competence), thereby considering both congruence and incongruence in adolescents’ and mothers’ reports of overprotective parenting. Our sample consisted of 402 mother-adolescent dyads (M adolescent age = 16.8 years, 63% female), who reported upon the mothers’ overprotective parenting. In addition, adolescents filled out questionnaires assessing their internalizing and externalizing problems and psychological need frustration. Data were analyzed using polynomial regressions with response surface analysis. Results showed evidence for a linear, additive relationship between adolescents’ and mothers’ reports of overprotective parenting, and adolescents’ internalizing and externalizing symptoms and relatedness and competence frustration. That is, higher scores in adolescents’ and mothers’ ratings of overprotective parenting were associated with more maladjustment and more need frustration. Moreover, results indicated that incongruence between adolescents’ and mothers’ reports related to more externalizing problems and more autonomy and relatedness frustration, and this was especially the case when adolescents perceived higher levels of overprotection than what was reported by mothers. These results underscore the importance of considering multiple perspectives when studying the dynamics involved in overprotective parenting

    Measurement of residual stresses around the notch of tensile specimens of the high-Cr tempered martensitic steel F82H-mod

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    Residual elastic strains were measured by neutron diffraction using POLDI facility at PSI-Switzerland on pre-loaded notched flat tensile specimens made of the high-chromium tempered martensitic steel F82H-mod steel. To calculate the residual stresses using Hooke’s equation, three perpendicular components of the residual strain field were determined. The measured residual strains and stresses were compared with those deduced from finite element simulation calculations. A very good agreement was found for the strains in the loading plane of the specimen while a somewhat larger discrepancy was observed for the out-of-plane residual strain, which was tentatively attributed to an uncertainty in the initial lattice spacing in that directio

    Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry.

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    BACKGROUND: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is often a life-threatening arrhythmia disorder with variable penetrance and expressivity. Little is known about the incidence or outcomes of CPVT patients with ≄2 variants. METHODS: The phenotypes, genotypes and outcomes of patients in the Pediatric and Congenital Electrophysiology Society CPVT Registry with ≄2 variants in genes linked to CPVT were ascertained. The American College of Medical Genetics & Genomics (ACMG) criteria and structural mapping were used to predict the pathogenicity of variants (3D model of pig RyR2 in open-state). RESULTS: Among 237 CPVT subjects, 193 (81%) had genetic testing. Fifteen patients (8%) with a median age of 9 years (IQR 5-12) had ≄2 variants. Sudden cardiac arrest occurred in 11 children (73%), although none died during a median follow-up of 4.3 years (IQR 2.5-6.1). Thirteen patients (80%) had at least two RYR2 variants, while the remaining two patients had RYR2 variants plus variants in other CPVT-linked genes. Among all variants identified, re-classification of the commercial laboratory interpretation using ACMG criteria led to the upgrade from variant of unknown significance (VUS) to pathogenic/likely pathogenic (P/LP) for 5 variants, and downgrade from P/LP to VUS for 6 variants. For RYR2 variants, 3D mapping using the RyR2 model suggested that 2 VUS by ACMG criteria were P/LP, while 2 variants were downgraded to likely benign. CONCLUSIONS: This severely affected cohort demonstrates that a minority of CPVT cases are related to ≄2 variants, which may have implications on family-based genetic counselling. While multi-variant CPVT patients were at high-risk for sudden cardiac arrest, there are insufficient data to conclude that this genetic phenomenon has prognostic implications at present. Further research is needed to determine the significance and generalizability of this observation. This study also shows that a rigorous approach to variant re-classification using the ACMG criteria and 3D mapping is important in reaching an accurate diagnosis, especially in the multi-variant population

    In situ uniaxial pressure cell for x-ray and neutron scattering experiments

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    We present an in situ uniaxial pressure device optimized for small angle x-ray and neutron scattering experiments at low-temperatures and high magnetic fields. A stepper motor generates force, which is transmitted to the sample via a rod with an integrated transducer that continuously monitors the force. The device has been designed to generate forces up to 200 N in both compressive and tensile configurations, and a feedback control allows operating the system in a continuous-pressure mode as the temperature is changed. The uniaxial pressure device can be used for various instruments and multiple cryostats through simple and exchangeable adapters. It is compatible with multiple sample holders, which can be easily changed depending on the sample properties and the desired experiment and allow rapid sample changes

    In situ uniaxial pressure cell for x-ray and neutron scattering experiments

    Get PDF
    We present an in situ uniaxial pressure device optimized for small angle x-ray and neutron scattering experiments at low-temperatures and high magnetic fields. A stepper motor generates force, which is transmitted to the sample via a rod with an integrated transducer that continuously monitors the force. The device has been designed to generate forces up to 200 N in both compressive and tensile configurations, and a feedback control allows operating the system in a continuous-pressure mode as the temperature is changed. The uniaxial pressure device can be used for various instruments and multiple cryostats through simple and exchangeable adapters. It is compatible with multiple sample holders, which can be easily changed depending on the sample properties and the desired experiment and allow rapid sample changes
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