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65th Annual Meeting of the German Society of Neuropathology and Neuroanatomy (DGNN) - Meeting Abstracts, September 1–3, 2021

Dear participants, dear colleagues, It is our great pleasure to welcome you to the 65th Annual Meeting of the German Society of Neuropathology and Neuroanatomy - the brain and nerve microenvironment in health and disease - which will be held as a virtual meeting from September 1–3, 2021. The meeting will bring together basic and clinical researchers, physicians as well as junior scientists and PhD students from different disciplines of basic and clinical neuroscience. We will have outstanding lectures by and with some of the most renowned international experts in the field of neuro-oncology, neuroinflammation, neurodegeneration and muscle and nerve diseases and look forward to exciting scientific discussions. There will also be a special and timely section on the effects of COVID-19 on the central and peripheral nervous system. The three days will offer exciting insights into different areas of basic and clinical neuroscience. We have also encouraged early career scientists to present their scientific findings in short talks and poster presentations. We are therefore particularly thankful that the abstracts of the meeting, which in their sum provide the best overview of the high scientific standing of the field, will be published in Free Neuropathology. Finally, we would like to thank you all for your active contribution to this conference in these difficult times. We also thank all supporters for their financial help. We wish you a stimulating and exciting conference. Yours sincerely, Prof. Dr. med. Till Acker Conference Chair (Justus Liebig University Giessen Dr. med. Anne Schänzer Dr. med. Hildegard Dohme

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European Society of Surgical Oncology's strategy for clinical research : Paving the way for a culture of research in cancer surgery

As part of its mission to promote the best surgical care for cancer patients, the European Society of Surgical Oncology (ESSO) has been developing multiple programmes for clinical research along with its educational portfolio. This position paper describes the different research activities of the Society over the past decade and an action plan for the upcoming five years to lead innovative and high quality surgical oncology research. ESSO proposes to consider pragmatic research methodologies as a complement to randomised clinical trials (RCT), advocates for increased funding and operational support in conducting research and aims to enable young surgeons to be active in research and establish partnerships for translational research activities. (C) 2019 Published by Elsevier Ltd.Peer reviewe

Motility and fertilizing capacity of boar semen stored in raffia palm (Raffia hookeri) sap extender at 15°C

Two separate experiments were conducted to test the ability of new semen extenders containing various levels of tropical raffia palm sap in sustaining the motility and fertilizing capacity of boar spermatozoa during storage at 15°C. Highly significant variations (P < 0.01) occurred in the ability of extenders to sustain progressive motility from days 1 to 4 of storage. One of the new extenders, raffia palm extender 2 (RPE–2) was superior to other trial extenders including the control (coconut milk extender, CME) in sustaining progressive motility of boar sperm from 24 - 72 h of storage; average motility scores at 24 and 72 h were 73.0 and 50.0% for RPE-2, 65.0 and 41.0% for CME (control), 55.0 and 36.0% for RPE-1 and 45.0 and 6.5% for RPE-0. Sperm tail vibratory movement was observed in sperm stored in RPE-1 and RPE-0 from day 2 of storage. Sperm in RPE-0 and RPE-1 lost motility completely at 96 h while motility of sperm in RPE-2 showed a sharp drop in motility values from 72 – 96 h relative to control. Average conception rates in 24 gilts inseminated per treatment with semen stored for 24, 48 and 72 h respectively were 83.3, 66.6 and 16.6% for RPE-2, 50, 16.6 and 0.0 percent for RPE-1, 16.6, 0.0 and 0.0% for RPE-0 and 75.0, 50.0 and 26.6% for CME (control). Average number of piglets born using semen stored for 24, 48 and 72 h respectively were 8.0, 8.0 and 6.5 for RPE-2 and 8.2, 8.2 and 6.0 for the control. RPE-2 supported better fetal survival rate than other trial extenders and control. Highly significant variations (P < 0.01) occurred among extenders in conception rate and number of piglets born. These results portray RPE-2 as a reliable short-term liquid semen storage medium for swine artificial insemination in the humid tropics

The growth performance of growing pigs during feed restriction and re-alimentation in a humid tropical environment

Thirty two crossbred (large white x landrace) pigs were used in a 56 days restriction and 56 days realimentation study to evaluate the effect of restricting growing pigs at 90, 80 and 70% of the ad libitumfeed intake of the control. The pigs averaged 35.23 ± 0.560 kg at the start of the study. There were four treatments (control, 90, 80 and 70%). Each treatment had eight pigs allotted to 2 replications of fourpigs each. The pigs received a 16% crude protein and 12.08 MJME/kg diet. Results indicated that average daily gains (ADG) of the control pigs were significantly superior to the others during the restriction period. However, at the end of the 56 days re-alimentation, pigs on the 80% and 70% feeding regime had superior ADG than the pigs on the control and 90 percent feeding regime. Data on the body length (BL) and height at shoulders (HS) followed the same trend as observed for ADG. Feed intakes of pigs were significantly affected during the restriction and re-alimentation period. There was a significant (p < 0.05) decrease in feed intake as level of restriction increased. Also, during realimentation pigs on the 70% level had the highest feed intake. Pigs on the 80% level of restriction had the best feed cost/kg gain values at restriction and re-alimentation. It is concluded that restrictinggrowing pigs at 80% of the ad libitum intake of the control yields best performance and economic benefit

The SSAI fully supports the suspension of hydroxyethyl-starch solutions commissioned by the European Medicines Agency

Non peer reviewe