8,356 research outputs found
Supersymmetry of the Schrodinger and PP Wave Solutions in Einstein-Weyl Supergravities
We obtain the Schrodinger and general pp-wave solutions with or without the
massive vector in Einstein-Weyl supergravity. The vector is an auxiliary field
in the off-shell supermultiplet and it acquires a kinetic term in the
Weyl-squared super invariant. We study the supersymmetry of these solutions and
find that turning on the massive vector has a consequence of breaking all the
supersymmetry. The Schrodinger and also the pp-wave solutions with the massive
vector turned off on the other hand preserve 1/4 of the supersymmetry.Comment: 13 pages, no figur
Critical and Non-Critical Einstein-Weyl Supergravity
We construct N=1 supersymmetrisations of some recently-proposed theories of
critical gravity, conformal gravity, and extensions of critical gravity in four
dimensions. The total action consists of the sum of three separately off-shell
supersymmetric actions containing Einstein gravity, a cosmological term and the
square of the Weyl tensor. For generic choices of the coefficients for these
terms, the excitations of the resulting theory around an AdS_4 background
describe massive spin-2 and massless spin-2 modes coming from the metric;
massive spin-1 modes coming from a vector field in the theory; and massless and
massive spin-3/2 modes (with two unequal masses) coming from the gravitino.
These assemble into a massless and a massive N=1 spin-2 multiplet. In critical
supergravity, the coefficients are tuned so that the spin-2 mode in the massive
multiplet becomes massless. In the supersymmetrised extensions of critical
gravity, the coefficients are chosen so that the massive modes lie in a
"window" of lowest energies E_0 such that these ghostlike fields can be
truncated by imposing appropriate boundary conditions at infinity, thus leaving
just positive-norm massless supergravity modes.Comment: 29 page
Observation of an unexpected third receptor molecule in the crystal structure of human interferon-γ receptor complex
AbstractBackground: Molecular interactions among cytokines and cytokine receptors form the basis of many cell-signaling pathways relevant to immune function. Interferon-γ (IFN-γ) signals through a multimeric receptor complex consisting of two different but structurally related transmembrane chains: the high-affinity receptor-binding subunit (IFN-γRα) and a species-specific accessory factor (AF-1 or IFN-γRβ). In the signaling complex, the two receptors probably interact with one another through their extracellular domains. Understanding the atomic interactions of signaling complexes enhances the ability to control and alter cell signaling and also provides a greater understanding of basic biochemical processes.Results: The crystal structure of the complex of human IFN-γ with the soluble, glycosylated extracellular part of IFN-γRα has been determined at 2.9 Å resolution using multiwavelength anomalous diffraction methods. In addition to the expected 2:1 complex, the crystal structure reveals the presence of a third receptor molecule not directly associated with the IFN-γ dimer. Two distinct intermolecular contacts, involving the edge strands of the C-terminal domains, are observed between this extra receptor and the 2:1 receptor–ligand complex thereby forming a 3:1 complex.Conclusions: The observed interactions in the 2:1 complex of the high-affinity cell-surface receptor with the IFN-γ cytokine are similar to those seen in a previously reported structure where the receptor chains were not glycosylated. The formation of β-sheet packing interactions between pairs of IFN-γRα receptors in these crystals suggests a possible model for receptor oligomerization of Rα and the structurally homologous Rβ receptors in the fully active IFN-γ signaling complex
Ontology based Approach for Precision Agriculture
In this paper, we propose a framework of knowledge for an agriculture
ontology which can be used for the purpose of smart agriculture systems. This
ontology not only includes basic concepts in the agricultural domain but also
contains geographical, IoT, business subdomains, and other knowledge extracted
from various datasets. With this ontology, any users can easily understand
agricultural data links between them collected from many different data
resources. In our experiment, we also import country, sub-country and disease
entities into this ontology as basic entities for building agricultural linked
datasets later
Predicting the solar maximum with the rising rate
The growth rate of solar activity in the early phase of a solar cycle has
been known to be well correlated with the subsequent amplitude (solar maximum).
It provides very useful information for a new solar cycle as its variation
reflects the temporal evolution of the dynamic process of solar magnetic
activities from the initial phase to the peak phase of the cycle. The
correlation coefficient between the solar maximum (Rmax) and the rising rate
({\beta}a) at {\Delta}m months after the solar minimum (Rmin) is studied and
shown to increase as the cycle progresses with an inflection point (r = 0.83)
at about {\Delta}m = 20 months. The prediction error of Rmax based on {\beta}a
is found within estimation at the 90% level of confidence and the relative
prediction error will be less than 20% when {\Delta}m \geq 20. From the above
relationship, the current cycle (24) is preliminarily predicted to peak around
October 2013 with a size of Rmax =84 \pm 33 at the 90% level of confidence.Comment: 7 pages, 3 figures, accepted for publication in SCIENCE CHINA
Physics,Mechanics & Astronom
Unsupervised segmentation of irradiation\unicode{x2010}induced order\unicode{x2010}disorder phase transitions in electron microscopy
We present a method for the unsupervised segmentation of electron microscopy
images, which are powerful descriptors of materials and chemical systems.
Images are oversegmented into overlapping chips, and similarity graphs are
generated from embeddings extracted from a domain\unicode{x2010}pretrained
convolutional neural network (CNN). The Louvain method for community detection
is then applied to perform segmentation. The graph representation provides an
intuitive way of presenting the relationship between chips and communities. We
demonstrate our method to track irradiation\unicode{x2010}induced amorphous
fronts in thin films used for catalysis and electronics. This method has
potential for "on\unicode{x2010}the\unicode{x2010}fly" segmentation to
guide emerging automated electron microscopes.Comment: 7 pages, 3 figures. Accepted to Machine Learning and the Physical
Sciences Workshop, NeurIPS 202
The languages of peace during the French religious wars
The desirability of peace was a common topos in sixteenth-century political rhetoric, and the duty of the king to uphold the peace for the benefit of his subjects was also a long-established tradition. However, the peculiar circumstances of the French religious wars, and the preferred royal policy of pacification, galvanized impassioned debate among both those who supported and those who opposed confessional coexistence. This article looks at the diverse ways in which peace was viewed during the religious wars through an exploration of language and context. It draws not only on the pronouncements of the crown and its officials, and of poets and jurists, but also on those of local communities and confessional groups. Opinion was not just divided along religious lines; political imperatives, philosophical positions and local conditions all came into play in the arguments deployed. The variegated languages of peace provide a social and cultural dimension for the contested nature of sixteenth-century French politics. However, they could not restore harmony to a war-torn and divided kingdom
De l'inefficacité du réseau social : des liens sociaux non mobilisés chez les patients atteints de cancer
International audienceDe nombreuses études sur les réseaux sociaux portent sur la question des ressources auxquelles un individu peut avoir accès à travers ses relations sociales. En s'intéressant aux réseaux qui ont « fonctionné », elles tentent alors de spécifier les facteurs ayant permis l'accès aux ressources. Mais peu de travaux se sont penchés sur les réseaux ayant échoué à fournir à l'individu le bien ou le service qu'il recherchait. Cet article se propose de discuter de ces réseaux « inefficaces » à travers le cas de patients atteints de cancer recherchant des informations relatives à leur pathologie. Les résultats indiquent que les causes de l'inefficacité du réseau sont à rechercher dans la non mobilisation des liens de la part des malades rencontrés. Un certain nombre de contraintes pèsent sur ces liens empêchant ainsi leur mobilisation
Salivary and gut microbiomes play a significant role in in vitro oral bioaccessibility, biotransformation, and intestinal absorption of arsenic from food
The release of a toxicant from a food matrix during the gastrointestinal digestion is a crucial determinant of the toxicant's oral bioavailability. We present a modified setup of the human simulator of the gut microbial ecosystem (SHIME), with four sequential gastrointestinal reactors (oral, stomach, small intestine, and colon), including the salivary and colonic microbiomes. Naturally arsenic-containing rice, mussels, and nori seaweed were digested in the presence of microorganisms and in vitro oral bioaccessibility, bioavailability, and metabolism of arsenic species were evaluated following analysis by using HPLC/mass spectrometry. When food matrices were digested with salivary bacteria, the soluble arsenic in the gastric digestion stage increased for mussel and nori samples, but no coincidence impact was found in the small intestinal and colonic digestion stages. However, the simulated small intestinal absorption of arsenic was increased in all food matrices (1.2-2.7 fold higher) following digestion with salivary microorganisms. No significant transformation of the arsenic species occurred except for the arsenosugars present in mussels and nori. In those samples, conversions between the oxo arsenosugars were observed in the small intestinal digestion stage whereupon the thioxo analogs became major metabolites. These results expand our knowledge on the likely metabolism and oral bioavailabiltiy of arsenic during human digestion, and provide valuable information for future risk assessments of dietary arsenic
- …