Perfil lipídico e uso de anti-TNF-α

AbstractThe use of anti-TNF-α has been associated with several changes in lipid profile, although some study results are conflicting. The knowledge of this fact is of great importance when one observes at the association between rheumatic diseases and accelerated atherogenesis. The aim of this analysis was search for changes in lipid profile in anti TNF-α users in the population of Southern Brazil and its association with duration of use, indications, patient gender and type of anti-TNF. For this purpose, we studied the profiles of total cholesterol (TC), HDL cholesterol (HDLc), LDL cholesterol (LDLc), atherogenic index (ATI) and triglycerides (TGs) of 58 patients (42 with rheumatoid arthritis and 16 with spondyloarthritis) before and after using this drug for a median of 16.0 months. There were no changes in the levels of TC, HDLc, LDLc and ATI (P=NS). However, there was a significant increase in TG levels (P=0.03). The median difference between first and second TG measurements was 16mg/dL and this increase was not associated with gender, time of use, use indication or type of anti TNF-α (P=NS). It was concluded that the use of anti TNF-α is associated with increased values of TG

A música como prática de promoção da saúde na adolescência

Aim: to understand the perception of adolescents, who participate in a choral singing, about the use of music as a tool to promote health. Method: a descriptive, exploratory, qualitative study, carried out with eight adolescents, members of a choral singing, in Chapecó-SC. The data collection was developed through the focus group with a script of guiding questions, in the first semester of 2017. The analysis and interpretation of the data were performed through content analysis. Results: adolescents conceptualized health as having healthy eating, sleeping, exercising and reported benefits of participating in choral singing such as relaxation, social integration, decreasing shyness and decreased anxiety. Final considerations: the practice of music, through choral singing, is able to promote health, bringing physical, emotional and social benefits, and regards to nursing the challenge of exploring the path of music in the promotion of adolescent health.Objetivo: comprender la percepción de los adolescentes, participantes de un coro, sobre de la utilización de la música como instrumento para promover la salud. Método: estudio descriptivo, exploratorio, de perspectiva cualitativa, realizado con ocho adolescentes, integrantes de un coro, en Chapecó-SC. La recolección de los datos se desarrolló por medio de grupo focal, en cual ser basó en un guion de cuestiones orientadoras, en el primer semestre de 2017. El análisis e interpretación de los datos se realizó por análisis de contenido. Resultados: los adolescentes conceptuaron salud como tener alimentación sana, dormir, hacer ejercicios físicos y relataron beneficios de la participación en el coro, como relajación, integración social, mejora de la timidez y disminución de la ansiedad. Consideraciones finales: la práctica de la música, por medio del coro, es una forma de promover la salud, proporcionando beneficios físicos, emocionales y sociales, resultando a la enfermería el desafío de conocer el camino de la música en la promoción de la salud de los adolescentes.Objetivo: compreender a percepção dos adolescentes participantes de um canto coral, acerca da utilização da música como instrumento para promover a saúde. Método: estudo do tipo descritivo, exploratório, com abordagem qualitativa, realizado com oito adolescentes, integrantes de um canto coral, em Chapecó-SC. A coleta dos dados desenvolveu-se por meio do grupo focal com um roteiro de questões norteadoras, no primeiro semestre de 2017. A análise e interpretação dos dados foram realizadas por intermédio da análise de conteúdo. Resultados: os adolescentes conceituaram saúde como ter alimentação saudável, dormir, fazer exercícios físicos e relataram benefícios da participação no canto coral como relaxamento, integração social, melhora da timidez e diminuição da ansiedade. Considerações finais: a prática da música, por meio do canto coral, é capaz de promover a saúde, trazendo benefícios físicos, emocionais e sociais, cabendo à enfermagem o desafio de desbravar o caminho da música na promoção da saúde dos adolescentes. Descritores: Adolescente; Música; Promoção da saúde

Atuação na oncologia pediátrica e a música como promotora de saúde: significados para os profissionais

Objetivo: Compreender os significados para os profissionais em trabalhar na oncologia pediátrica e em utilizar a música como promotora de saúde no ambiente hospitalar. Método: Estudo descritivo, exploratório, de abordagem qualitativa, fundamentado nos pressupostos teóricos do Interacionismo Simbólico, realizado com 10 profissionais do setor da oncologia pediátrica do maior hospital regional infantil do Oeste catarinense. A coleta de dados ocorreu, por meio de uma entrevista semiestruturada com cada profissional. Os dados foram analisados conforme análise de conteúdo, direcionada para a categoria temática. Resultados: Trabalhar na oncologia pediátrica mostrou demandar dedicação dos profissionais, além da formação do vínculo para haver confiança e apoio entre equipe de cuidado, indivíduos hospitalizados e familiares. É um setor com possibilidades para promover saúde, por meio do conforto, orientações e pelas diversas ações que proporcionam distração, como a música. Conclusão: Atuar na pediatria oncológica é gratificante, com aprendizado constante, sendo que a música é um instrumento para promover saúde no setor, pois oportuniza o relaxamento, distração, reflexões, esperança e ânimo para aqueles que a ouvem, possibilitando humanização na assistência em saúde no ambiente hospitalar

Hospitalização e música: significados dos familiares de crianças e adolescentes com câncer

Objective: to understand the meanings of the hospitalization process and the use of music as a health promoter, in the perception of family members of children and adolescents undergoing cancer treatment. Method: exploratory, descriptive research, with a qualitative approach, based on the assumptions of Health Promotion and Symbolic Interactionism, which had ten family members as participants. Data collection took place through semi-structured interviews and were analyzed according to content analysis. Results: Three categories emerged, in which family members present the meanings of hospitalization and its changes, music as a health promotion instrument, their experiences of improvement and quality of life provided by this tool. Conclusion: family members understood the hospitalization process as a mixture of feelings and sensations, highlighting music as a care technology that promotes well-being, joy, hope and that can be used in the hospital environment, in the oncology sector.Objetivo: compreender os significados do processo de hospitalização e da utilização da música como promotora da saúde, na percepção de familiares de crianças e adolescentes que se encontram em tratamento oncológico.  Método: pesquisa do tipo exploratória, descritiva, de abordagem qualitativa, fundamentada nos pressupostos da Promoção da Saúde e do Interacionismo Simbólico, a qual teve como participantes dez familiares. A coleta de dados ocorreu por meio de entrevista semiestruturada e foram analisados conforme a análise de conteúdo. Resultados: emergiram três categorias, sendo que os familiares desvelaram os significados da hospitalização e suas mudanças, a música como instrumento de promoção da saúde, suas experiências de melhora e qualidade de vida proporcionada por essa ferramenta. Conclusão: os familiares significaram o processo de hospitalização como um misto de sentimentos e sensações, destacando a música como uma tecnologia de cuidado que promove bem-estar, alegria, esperança e que pode ser empregada no ambiente hospitalar, no setor oncológico

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Mapping density, diversity and species-richness of the Amazon tree flora

Using 2.046 botanically-inventoried tree plots across the largest tropical forest on Earth, we mapped tree species-diversity and tree species-richness at 0.1-degree resolution, and investigated drivers for diversity and richness. Using only location, stratified by forest type, as predictor, our spatial model, to the best of our knowledge, provides the most accurate map of tree diversity in Amazonia to date, explaining approximately 70% of the tree diversity and species-richness. Large soil-forest combinations determine a significant percentage of the variation in tree species-richness and tree alpha-diversity in Amazonian forest-plots. We suggest that the size and fragmentation of these systems drive their large-scale diversity patterns and hence local diversity. A model not using location but cumulative water deficit, tree density, and temperature seasonality explains 47% of the tree species-richness in the terra-firme forest in Amazonia. Over large areas across Amazonia, residuals of this relationship are small and poorly spatially structured, suggesting that much of the residual variation may be local. The Guyana Shield area has consistently negative residuals, showing that this area has lower tree species-richness than expected by our models. We provide extensive plot meta-data, including tree density, tree alpha-diversity and tree species-richness results and gridded maps at 0.1-degree resolution

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time, and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space. While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes, vast areas of the tropics remain understudied. In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity, but it remains among the least known forests in America and is often underrepresented in biodiversity databases. To worsen this situation, human-induced modifications may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge, it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost