2,086 research outputs found
Prevalence of IgG antibodies against Borrelia Burgdorferi s.l. and Ehrlichia Phagocytophila in sera of patients presenting symptoms of Lyme disease in a central region of Italy.
The aim of this study was to evaluate the prevalence (seroprevalence) of antibodies against Borrelia burgdorferi and Ehrlichia phagocytophila among patients resident in Lazio, a region of central Italy. Of a sample of 1,050 patients, which presented clinical manifestations related to Lyme disease, 34 (3.2%) were Borrelia-seropositive (Lyme index value ≥ 1.2). The sera of 25 out of the 34 patients that were Borrelia-positive were also analysed for the presence of antibodies against E. phagocytophila and 3 (12%) were found Ehrlichia-positive (titres >1:64). No Ehrlichia-positive samples were found among sera of 250 Borrelia-negative patients. Since both B. burgdorferi s.l. and Ehrlichia species share the same tick vector ( Ixodes ricinus), our results indicate that concurrent transmission of these microbial pathogens might have been occurred among the patients included in this study
Implementación de receta digital en Swiss Medical, Argentina
La prescripción de un fármaco es un acto médico y administrativo. La prescripción electrónica genera menor riesgo de errores de legibilidad en la dispensación, administración de medicamentos, y permitiendo utilizar sistemas de soporte a toma de decisiones. Asimismo, evitan problemas de facturación y posibles fraudes.
En marzo de 2016 Swiss Medical y DXC.technology se implementó la Historia ClÃnica Electrónica, donde se puede acceder al historial del paciente y contar con sistemas de alertas de duplicidad de principio activo y dosis máxima.
En agosto de 2018 se inició el proyecto de telemedicina y receta digital, con atención a pacientes pediátricos y adultos afiliados. En la cual se genera la receta por nombre genérico (Ley 25.649), con firma digital (Ley 25.506), enviando la receta y las indicaciones médicas al paciente, para que accedan a cualquier farmacia de la red de Farmalink para adquirir el fármaco prescrito.Sociedad Argentina de Informática e Investigación Operativ
AGILE detection of delayed gamma-ray emission from GRB 080514B
GRB 080514B is the first gamma ray burst (GRB), since the time of EGRET, for
which individual photons of energy above several tens of MeV have been detected
with a pair-conversion tracker telescope. This burst was discovered with the
Italian AGILE gamma-ray satellite. The GRB was localized with a cooperation by
AGILE and the interplanetary network (IPN). The gamma-ray imager (GRID)
estimate of the position, obtained before the SuperAGILE-IPN localization, is
found to be consistent with the burst position. The hard X-ray emission
observed by SuperAGILE lasted about 7 s, while there is evidence that the
emission above 30 MeV extends for a longer duration (at least ~13 s). Similar
behavior was seen in the past from a few other GRBs observed with EGRET.
However, the latter measurements were affected, during the brightest phases, by
instrumental dead time effects, resulting in only lower limits to the burst
intensity. Thanks to the small dead time of the AGILE/GRID we could assess that
in the case of GRB 080514B the gamma-ray to X-ray flux ratio changes
significantly between the prompt and extended emission phase.Comment: A&A letters, in pres
Direct Evidence for Hadronic Cosmic-Ray Acceleration in the Supernova Renmant IC 443
The Supernova Remnant (SNR) IC 443 is an intermediate-age remnant well known
for its radio, optical, X-ray and gamma-ray energy emissions. In this Letter we
study the gamma-ray emission above 100 MeV from IC 443 as obtained by the AGILE
satellite. A distinct pattern of diffuse emission in the energy range 100 MeV-3
GeV is detected across the SNR with its prominent maximum (source "A")
localized in the Northeastern shell with a flux F = (47 \pm 10) 10^{-8} photons
cm^{-2} s^{-1} above 100 MeV. This location is the site of the strongest shock
interaction between the SNR blast wave and the dense circumstellar medium.
Source "A" is not coincident with the TeV source located 0.4 degree away and
associated with a dense molecular cloud complex in the SNR central region. From
our observations, and from the lack of detectable diffuse TeV emission from its
Northeastern rim, we demonstrate that electrons cannot be the main emitters of
gamma-rays in the range 0.1-10 GeV at the site of the strongest SNR shock. The
intensity, spectral characteristics, and location of the most prominent
gamma-ray emission together with the absence of co-spatial detectable TeV
emission are consistent only with a hadronic model of cosmic-ray acceleration
in the SNR. A high-density molecular cloud (cloud "E") provides a remarkable
"target" for nucleonic interactions of accelerated hadrons: our results show
enhanced gamma-ray production near the molecular cloud/shocked shell
interaction site. IC 443 provides the first unambiguous evidence of cosmic-ray
acceleration by SNRs.Comment: 5 pages, 2 figures; accepted by ApJLetters on Jan 21, 201
Episodic Transient Gamma-Ray Emission from the Microquasar Cygnus X-1
Cygnus X-1 is the archetypal black hole (BH) binary system in our Galaxy. We
report the main results of an extensive search for transient gamma-ray emission
from Cygnus X-1 carried out in the energy range 100 MeV - 3 GeV by the AGILE
satellite, during the period 2007 July - 2009 October. The total exposure time
is about 300 days, during which the source was in the "hard" X-ray spectral
state. We divided the observing intervals in 2 or 4 week periods, and searched
for transient and persistent emission. We report an episode of significant
transient gamma-ray emission detected on 2009, October 16 in a position
compatible with Cygnus X-1 optical position. This episode, occurred during a
hard spectral state of Cygnus X-1, shows that a 1-2 day time variable emission
above 100 MeV can be produced during hard spectral states, having important
theoretical implications for current Comptonization models for Cygnus X-1 and
other microquasars. Except for this one short timescale episode, no significant
gamma-ray emission was detected by AGILE. By integrating all available data we
obtain a 2 upper limit for the total integrated flux of
in the energy range
100 MeV - 3 GeV. We then clearly establish the existence of a spectral cutoff
in the energy range 1-100 MeV that applies to the typical hard state outside
the flaring period and that confirms the historically known spectral cutoff
above 1 MeV.Comment: Accepted for publication by ApJ on the 9th of Feb 2010, 5 pages, 3
figure
Calibration of AGILE-GRID with In-Flight Data and Monte Carlo Simulations
Context: AGILE is a gamma-ray astrophysics mission which has been in orbit
since 23 April 2007 and continues to operate reliably. The gamma-ray detector,
AGILE-GRID, has observed Galactic and extragalactic sources, many of which were
collected in the first AGILE Catalog. Aims: We present the calibration of the
AGILE-GRID using in-flight data and Monte Carlo simulations, producing
Instrument Response Functions (IRFs) for the effective area A_eff), Energy
Dispersion Probability (EDP), and Point Spread Function (PSF), each as a
function of incident direction in instrument coordinates and energy. Methods:
We performed Monte Carlo simulations at different gamma-ray energies and
incident angles, including background rejection filters and Kalman filter-based
gamma-ray reconstruction. Long integrations of in-flight observations of the
Vela, Crab and Geminga sources in broad and narrow energy bands were used to
validate and improve the accuracy of the instrument response functions.
Results: The weighted average PSFs as a function of spectra correspond well to
the data for all sources and energy bands. Conclusions: Changes in the
interpolation of the PSF from Monte Carlo data and in the procedure for
construction of the energy-weighted effective areas have improved the
correspondence between predicted and observed fluxes and spectra of celestial
calibration sources, reducing false positives and obviating the need for
post-hoc energy-dependent scaling factors. The new IRFs have been publicly
available from the Agile Science Data Centre since November 25, 2011, while the
changes in the analysis software will be distributed in an upcoming release
The flaring blazars of the first 1.5 years of the AGILE mission
We report the AGILE gamma-ray observations and the results of the
multiwavelength campaigns on seven flaring blazars detected by the mission:
During two multiwavelength campaigns, we observed gamma-ray activity from two
Flat Spectrum Radio Quasars of the Virgo region, e.g. 3C 279 and 3C 273 (the
latter being the first extragalactic source simultaneously observed with the
gamma-ray telescope and the hard X ray imager of the mission). Due to the large
FOV of the AGILE/GRID instrument, we achieved an almost continuous coverage of
the FSRQ 3C 454.3. The source showed flux above 10E-6 photons/cm2/s (E > 100
MeV) and showed day by day variability during all the AGILE observing periods.
In the EGRET era, the source was found in high gamma-ray activity only once. An
other blazar, PKS 1510-089 was frequently found in high gamma-ray activity. S5
0716+71, an intermediate BL Lac object, exhibited a very high gamma-ray
activity and fast gamma-ray variability during a period of intense optical
activity. We observed high gamma-ray activity from W Comae, a BL Lac object,
and Mrk 421, an high energy peaked BL Lac object. For this source, a
multiwavelength campaign from optical to TeV has been performed
Gamma-Ray Localization of Terrestrial Gamma-Ray Flashes
Terrestrial Gamma-Ray Flashes (TGFs) are very short bursts of high energy
photons and electrons originating in Earth's atmosphere. We present here a
localization study of TGFs carried out at gamma-ray energies above 20 MeV based
on an innovative event selection method. We use the AGILE satellite Silicon
Tracker data that for the first time have been correlated with TGFs detected by
the AGILE Mini-Calorimeter. We detect 8 TGFs with gamma-ray photons of energies
above 20 MeV localized by the AGILE gamma-ray imager with an accuracy of 5-10
degrees at 50 MeV. Remarkably, all TGF-associated gamma rays are compatible
with a terrestrial production site closer to the sub-satellite point than 400
km. Considering that our gamma rays reach the AGILE satellite at 540 km
altitude with limited scattering or attenuation, our measurements provide the
first precise direct localization of TGFs from space.Comment: 5 pages, 4 figures, 1 table, available at
http://prl.aps.org/abstract/PRL/v105/i12/e12850
Detection of Gamma-ray Emission from the Eta-Carinae Region
We present the results of extensive observations by the gamma-ray AGILE
satellite of the Galactic region hosting the Carina nebula and the remarkable
colliding wind binary Eta Carinae (Eta Car) during the period 2007 July to 2009
January. We detect a gamma-ray source (1AGL J1043-5931) consistent with the
position of Eta Car. If 1AGL J1043-5931 is associated with the Eta Car system
our data provide the long sought first detection above 100 MeV of a colliding
wind binary. The average gamma-ray flux above 100 MeV and integrated over the
pre-periastron period 2007 July to 2008 October is F = (37 +/- 5) x 10-8 ph
cm-2 s-1 corresponding to an average gamma-ray luminosity of L = 3.4 x 10^34
erg s-1 for a distance of 2.3 kpc. We also report a 2-day gamma-ray flaring
episode of 1AGL J1043-5931 on 2008 Oct. 11-13 possibly related to a transient
acceleration and radiation episode of the strongly variable shock in the
system.Comment: 5 pages, 4 figure, accepted for publication in ApJ Letter
Agile Detection of Delayed Gamma-Ray Emission from the Short Gamma-Ray Burst GRB 090510
Short gamma-ray bursts (GRBs), typically lasting less than 2 s, are a special
class of GRBs of great interest. We report the detection by the AGILE satellite
of the short GRB 090510 which shows two clearly distinct emission phases: a
prompt phase lasting ~ 200 msec and a second phase lasting tens of seconds. The
prompt phase is relatively intense in the 0.3-10 MeV range with a spectrum
characterized by a large peak/cutoff energy near 3 MeV, in this phase, no
significant high-energy gamma-ray emission is detected. At the end of the
prompt phase, intense gamma-ray emission above 30 MeV is detected showing a
power-law time decay of the flux of the type t^-1.3 and a broad-band spectrum
remarkably different from that of the prompt phase. It extends from sub-MeV to
hundreds of MeV energies with a photon index alpha ~ 1.5. GRB 090510 provides
the first case of a short GRB with delayed gamma-ray emission. We present the
timing and spectral data of GRB 090510 and briefly discuss its remarkable
properties within the current models of gamma-ray emission of short GRBs.Comment: Accepted by the Astrophysical Journal Letters on September 11, 200
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