PERCEPÇÃO DOS ACADÊMICOS DE ODONTOLOGIA DA UNIVERSIDADE ESTADUAL DE FEIRA DE SANTANA SOBRE A IMPORTÂNCIA DO BANCO DE DENTES HUMANOS – UEFS

Um Banco de Dentes Humanos (BDH) consoante a Nassif et al.(2003, pg.70) “é uma instituição sem fins lucrativos, que deve estar vinculada a uma faculdade, universidade ou outra instituição” com a finalidade de fornecer aos pesquisadores e acadêmicos de odontologia unidades dentais para atividades científicas ou didáticas de forma legal e ética, abolindo consequentemente, o comércio ilegal de dentes, visto que, de acordo com a lei n.º 9.434 criada em 4 de fevereiro de 1997, o emprego de órgão outecido sem origem comprovada é considerada crime

Huntington's Disease: Two-Year Observational Follow-Up of Executive Function Evaluation with CNS Vital Signs Test in an Adult Patient

Huntington's disease (HD) is a genetic, degenerative, and progressive central nervous system disease. It is characterized by motor abnormalities and cognitive and psychiatric symptoms. Objective. To describe the precise degree of clinical severity of patients with HD through a new neurocognitive assessment. Methods. Unprecedented battery of computerized tests, CNSVS (Central Nervous System Vital Signs), was applied at three different moments in 2008, 2009, and 2010. The accurate and reliable CNSVS objectively provided the cognitive state of patients and allowed for the evaluation of disease progression. Case Report. P., 26, female, without any medication, with normal psychomotor development is a parent carrier of HD. In 2008, she was diagnosed with HD in accordance with the Medical Genetics Laboratories. Conclusion. The tests may be useful to reveal the exact measure of the current evolutionary stage of HD patients, allowing for more efficient planning of treatment and future procedures, such as the medication, therapy, and physical activity to be administered

EXPERIÊNCIA DE UMA CIRURGIÃ-DENTISTA NA RESIDÊNCIA EM SAÚDE DA FAMÍLIA EM CONSULTAS COMPARTILHADAS DE PRÉ-NATAL

Aim:To report the experience of a dentist performing shared prenatal consultations at a Family Health Unit in the interior of Bahia. Method: Experience report type study aboutshared querieswhatwere planned based on the observation of the need for promotion and prevention in the oral health of pregnant women, which took place weekly from November 2020 to March 2021. The consultations were shared between the resident surgeon-dentist and the nurse, with care approaches related to different professional knowledge. Results: The shared appointments allowed a space for oral health promotion and prevention; perception of the strengthening of the bond between pregnant women and the dentist; expansion of access to dental services by patients, reflecting positively on the indicator of the proportion of pregnant women who had a dental appointment, with a progressive increase from 8% in the 2nd quarter of 2020 to 62% in the 2nd quarter of 2021, in addition to favoring training as a resident in understanding the importance of shared consultation in search of comprehensive care and strengthening of health services. Final considerations: Primary Health Care (PHC) is a privileged space to reorient care practices, being necessary, recognize the community's health demands for planning and coordinating care. The shared consultations increased the pregnant women's adherence to dental care, enabling sensitization them for oral health care and attention, despite the stigmas related to dental treatment in pregnant women.Objetivo: Relatar a experiência de uma cirurgiã-dentista na realização de consultas compartilhadas de pré-natal,  numa Unidade de Saúde da Família, no interior da Bahia. Método: Estudo do tipo relato de experiência acerca de consultas compartilhadas que foram planejadas a partir da observação da necessidade da promoção e prevenção em saúde bucal das gestantes, que aconteceram semanalmente no período de novembro de 2020 a março de 2021. As consultas foram compartilhadas entre a residente cirurgiã-dentista e a enfermeira, com abordagens de cuidado relacionadas aos diferentes saberes profissionais. Resultados: As consultas compartilhadas permitiram um espaço de promoção e prevenção em saúde bucal; percepção do fortalecimento do vínculo entre as gestantes e a dentista; ampliação do acesso aos serviços odontológicos pelas pacientes, refletindo positivamente no indicador de proporção gestantes que passaram por consulta odontológica com aumento progressivo de 8% no 2º quadrimestre de 2020 para 62% no 2º quadrimestres de 2021, além de favorecer a formação enquanto residente na compreensão da importância da consulta compartilhada em busca da integralidade do cuidado e do fortalecimento do serviços de saúde Considerações finais: A Atenção Primária em Saúde (APS) é um espaço privilegiado para reorientar práticas de cuidados, sendo necessário, reconhecer as demandas de saúde da comunidade para o planejamento e coordenação do cuidado. As consultas compartilhadas aumentaram a adesão das gestantes ao cuidado odontológico, possibilitando sensibilizá-las para o cuidado e atenção com a saúde bucal, apesar dos estigmas relacionados ao tratamento odontológico em gestantes

Long-term interdisciplinary therapy reduces endotoxin level and insulin resistance in obese adolescents

Aim: the purpose of the present study was to assess the dietary fat intake, glucose, insulin, Homeostasis model assessment for insulin resistance HOMA-IR, and endotoxin levels and correlate them with adipokine serum concentrations in obese adolescents who had been admitted to long-term interdisciplinary weight-loss therapy.Design: the present study was a longitudinal clinical intervention of interdisciplinary therapy. Adolescents (n = 18, aged 15-19 y) with a body mass index >95th percentile were admitted and evaluated at baseline and again after 1 year of interdisciplinary therapy. We collected blood samples, and IL-6, adiponectin, and endotoxin concentrations were measured by ELISA. Food intake was measured using 3-day diet records. in addition, we assessed glucose and insulin levels as well as the homeostasis model assessment for insulin resistance (HOMA-IR).Results: the most important finding from the present investigation was that the long-term interdisciplinary lifestyle therapy decreased dietary fat intake and endotoxin levels and improved HOMA-IR. We observed positive correlations between dietary fat intake and endotoxin levels, insulin levels, and the HOMA-IR. in addition, endotoxin levels showed positive correlations with IL-6 levels, insulin levels and the HOMA-IR. Interestingly, we observed a negative correlation between serum adiponectin and both dietary fat intake and endotoxin levels.Conclusions: the present results indicate an association between dietary fat intake and endotoxin level, which was highly correlated with a decreased pro-inflammatory state and an improvement in HOMA-IR. in addition, this benefits effect may be associated with an increased adiponectin level, which suggests that the interdisciplinary therapy was effective in improving inflammatory pathways.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Dept Fisiol, São Paulo, BrazilDept Biociencias, São Paulo, BrazilDept Psicobiol, São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, São Paulo, BrazilICB Univ São Paulo USP, Grp Metab & Canc, São Paulo, BrazilUniv So Santa Catarina, Hlth Sci Unit, Lab Exercise Biochem & Physiol, Criciuma, SC, BrazilUniversidade Federal de São Paulo UNIFESP, São Paulo, BrazilFAPESP: 2011/50356-0FAPESP: 2011/50414-0Web of Scienc

Psychopharmacotherapy of panic disorder: 8-week randomized trial with clonazepam and paroxetine

The objective of the present randomized, open-label, naturalistic 8-week study was to compare the efficacy and safety of treat- ment with clonazepam (N = 63) and paroxetine (N = 57) in patients with panic disorder with or without agoraphobia. Efficacy assessment included number of panic attacks and clinician ratings of the global severity of panic disorders with the clinical global impression (CGI) improvement (CGI-I) and CGI severity (CGI-S) scales. Most patients were females (69.8 and 68.4% in the clonazepam and paroxetine groups, respectively) and age (mean ± SD) was 35.9 ± 9.6 years for the clonazepam group and 33.7 ± 8.8 years for the paroxetine group. Treatment with clonazepam versus paroxetine resulted in fewer weekly panic attacks at week 4 (0.1 vs 0.5, respectively; P < 0.01), and greater clinical improvements at week 8 (CGI-I: 1.6 vs 2.9; P = 0.04). Anxiety severity was significantly reduced with clonazepam versus paroxetine at weeks 1 and 2, with no difference in panic disorder severity. Patients treated with clonazepam had fewer adverse events than patients treated with paroxetine (73 vs 95%; P = 0.001). The most common adverse events were drowsiness/fatigue (57%), memory/concentration difficulties (24%), and sexual dysfunction (11%) in the clonazepam group and drowsiness/fatigue (81%), sexual dysfunction (70%), and nausea/vomiting (61%) in the paroxetine group. This naturalistic study confirms the efficacy and tolerability of clonazepam and paroxetine in the acute treatment of patients with panic disorder

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio