Mediterranean diet impact on cardiovascular diseases: a narrative review

: Cardiovascular disease (CVD) accounts for more than 17 million deaths per year worldwide. It has been estimated that the influence of lifestyle on CVD mortality amounts to 13.7% for smoking, 13.2% for poor diet, and 12% for inactive lifestyle. These results deeply impact both the healthy status of individuals and their skills in working. The impact of CVD on productivity loss accounts for the 24% in total costs for CVD management.Mediterranean diet (MedD) can positively impact on natural history of CVD. It is characterized by a relatively high consumption of inexpensive and genuine food such as cereals, vegetables, legumes, nuts, fish, fresh fruits, and olive oil as the principal source of fat, low meat consumption and low-to-moderate consumption of milk, dairy products, and wine.Its effects on cardiovascular health are related to the significant improvements in arterial stiffness. Peripheral artery disease, coronary artery disease, and chronic heart failure are all positively influenced by the MedD. Furthermore, MedD lowers the risk of sudden cardiac death due to arrhythmias.The present narrative review aims to analyze the effects of MedD on CVD

Myopericarditis in a Male Adolescent Following the Second Shot of COVID-19 Pfizer m-RNA Vaccine: Typical Example and Analysis of 110 Single Case Reports

One of the most powerful weapons against COVID-19 is vaccines. After the worldwide spread of the disease, m-RNA vaccines were authorized not only in adult patients, but also in children and adolescents aged 12–18. Since then, alarming reports of cases of myocarditis and/or pericarditis have been noted, primarily involving males after the second vaccine shot. A typical example of myopericarditis occurring in an adolescent a few days after the second shot of an m-RNA vaccine is described here. An in-depth review of all 110 single case reports published up to July 2022 with related features and outcomes is also presented. This is the first extensive analysis focused solely on a significant number of single case reports, which have usually been excluded from systematic reviews and meta-analyses carried out in the field. The analysis presented here confirms that most cases occurred in males after the second injection of an m-RNA vaccine. Cases were mild and responsive to the usual medical treatment. What is newly reported is that not only adolescents, but also older people, especially females, were affected by this adverse event

Effects of an adapted physical training on functional status, body composition and quality of life in persons with spinal cord injury paraplegia: a pilot study

AIM: Several studies have shown that strategies of health promotion, such as fitness programs, may improve quality of life in individuals with spinal cord injuries (SCI). However, the effects of specific adapted physical activity (APA) programs is almost unexplored. The aim of this paper was to evaluate the effects of an APA program on body composition, cardiovascular and fitness profile in SCI individuals with paraplegia. METHODS: Sixteen men with SCI paraplegia were enrolled. We studied the anthropometric, glucidic and lipid profile, body composition, strength and energy expenditure, depression levels and QoL. RESULTS: A significant reduction in fat mass and lipid profile was observed (P<0.05) with a significant increase in muscle strength and in arm circumference (P<0.05). The total daily energy expenditure and the number of the movements carried out in a typical day were significant increased (P<0.05). With regard to QoL and depression a significant improvement was registered. CONCLUSION: These findings support the use of APA as an effective strategy for health promotion, probably decreasing the risk of cardiovascular disease in people with SCI

Back surface measurements by rasterstereography for adolescent idiopathic scoliosis: from reproducibility to data reduction analyses

Purpose: Aim of this cross-sectional study was to evaluate the reproducibility of back surface measurements obtained by rasterstereography (RS) in adolescents with idiopathic scoliosis (AIS), and to identify the most informative RS parameters through a multi-step reduction analysis approach. Methods: Sixty-six AIS were assessed with a RS scanner. The assessment was repeated in the same day 15 min after the first scan and after 1 week. Intraclass-correlation analyses were conducted to verify the consistency of the measurements. A multi-step reduction technique including correlation, principal component analysis (PCA) and regression was employed to extract a core-set of key RS parameters. Results: Back surface measures were obtained from 66 AIS aged 10–17 years (median 13), with a mild Scoliosis angle < 25 (median 20). The reliability over the 3 sessions proved high to very high, with all the intraclass correlation coefficients ≥ 0.8 and 32 out of 48 coefficients ≥ 0.9. Only 8 of the 12 parameters provided by the RS device showed significant inter-item correlations and were therefore considered for further analyses. PCA extracted 4 of them, which entered the final regression analysis. High beta coefficients were found for 2 predictors: “Surface rotation-rms” and “Side deviation-rms,” which were found to be significantly associated with the dependent variable “Scoliosis angle.” Conclusions: Data showed that RS measurements are reliable in AIS with mild severity of scoliosis. “Surface rotation” and “Side deviation” were the best descriptors of the Scoliosis angle and should be considered as key parameters when surveilling AIS with mild curves by RS surface topography. Graphical abstract: These slides can be retrieved under Electronic Supplementary Material. [Figure not available: see fulltext.