Case Report Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab

is properly cited. Acremonium spp. are filamentous, cosmopolitan fungi commonly isolated from plant debris and soil. They are infrequent pathogens in humans. Acremonium fungemia has been reported in neutropenic patients associated with central venous catheters and in nonneutropenic patients receiving long-term total parenteral nutrition. TNF-α blockade is associated with fungal infections, but no Acremonium spp. infection had been reported up to the present. In this paper, we present a patient with ulcerative colitis who developed Acremonium kiliense fungemia associated with infliximab therapy while receiving total parenteral nutrition. The patient was successfully treated with voriconazole. Acremonium sp. infection must be suspected as another cause of fungal infection in patients under treatment with infliximab

Drilling-induced and logging-related features illustrated from IODP-ICDP Expedition 364 downhole logs and borehole imaging tools

Expedition 364 was a joint IODP and ICDP mission-specific platform (MSP) expedition to explore the Chicxulub impact crater buried below the surface of the Yucatán continental shelf seafloor. In April and May 2016, this expedition drilled a single borehole at Site M0077 into the crater's peak ring. Excellent quality cores were recovered from ~ 505 to ~1335m below seafloor (m b.s.f.), and high-resolution open hole logs were acquired between the surface and total drill depth. Downhole logs are used to image the borehole wall, measure the physical properties of rocks that surround the borehole, and assess borehole quality during drilling and coring operations. When making geological interpretations of downhole logs, it is essential to be able to distinguish between features that are geological and those that are operation-related. During Expedition 364 some drilling-induced and logging-related features were observed and include the following: effects caused by the presence of casing and metal debris in the hole, logging-tool eccentering, drilling-induced corkscrew shape of the hole, possible re-magnetization of low-coercivity grains within sedimentary rocks, markings on the borehole wall, and drilling-induced changes in the borehole diameter and trajectory

Early paleocene paleoceanography and export productivity in the Chicxulub crater

The Chicxulub impact caused a crash in productivity in the world''s oceans which contributed to the extinction of ~75% of marine species. In the immediate aftermath of the extinction, export productivity was locally highly variable, with some sites, including the Chicxulub crater, recording elevated export production. The long-term transition back to more stable export productivity regimes has been poorly documented. Here, we present elemental abundances, foraminifer and calcareous nannoplankton assemblage counts, total organic carbon, and bulk carbonate carbon isotope data from the Chicxulub crater to reconstruct changes in export productivity during the first 3 Myr of the Paleocene. We show that export production was elevated for the first 320 kyr of the Paleocene, declined from 320 kyr to 1.2 Myr, and then remained low thereafter. A key interval in this long decline occurred 900 kyr to 1.2 Myr post impact, as calcareous nannoplankton assemblages began to diversify. This interval is associated with fluctuations in water column stratification and terrigenous flux, but these variables are uncorrelated to export productivity. Instead, we postulate that the turnover in the phytoplankton community from a post-extinction assemblage dominated by picoplankton (which promoted nutrient recycling in the euphotic zone) to a Paleocene pelagic community dominated by relatively larger primary producers like calcareous nannoplankton (which more efficiently removed nutrients from surface waters, leading to oligotrophy) is responsible for the decline in export production in the southern Gulf of Mexico. © 2021. American Geophysical Union. All Rights Reserved

The Long-Term Consequences of the Global 1918 Influenza Pandemic: A Systematic Analysis of 117 IPUMS International Census Data Sets

Several country-level studies, including a prominent one for the United States, have identified long-term effects of in-utero exposure to the 1918 influenza pandemic (also known as the Spanish Flu) on economic outcomes in adulthood. In-utero conditions are theoretically linked to adult health and socioeconomic status through the fetal origins or Barker hypothesis. Historical exposure to the Spanish Flu provides a natural experiment to test this hypothesis. Although the Spanish Flu was a global phenomenon, with around 500 million people infected worldwide, there exists no comprehensive global study on its long-term economic effects. We attempt to close this gap by systematically analyzing 117 Census data sets provided by IPUMS International. We do not find consistent global long-term effects of influenza exposure on education, employment and disability outcomes. A series of robustness checks does not alter this conclusion. Our findings indicate that the existing evidence on long-term economic effects of the Spanish Flu is likely a consequence of publication bias

From global health security to global health solidarity, security and sustainability

The connotation of the word ‘security’ which often translates into a restrictive use of the term “global health security” tends to mask these core assumptions and perpetuates a state-centric approach focused on the viewpoint of the global North. We believe that the use of the concept of global health solidarity, security, and sustainability will provide a clearer outlook and more efficient basis to tackle “global health security” at the level of science as well as at the level of global public health action

Geophysical signature of the Tunnunik impact structure, Northwest Territories, Canada

International audienceIn 2011, the discovery of shatter cones confirmed the 28 km-diameter Tunnunik complex impact structure, Northwest Territories, Canada. This study presents the first results of ground-based electromagnetic, gravimetric and magnetic surveys over this impact structure. Its central area ischaracterized by a ~10 km wide negative gravity anomaly of about 3 mGal amplitude, roughly corresponding to the area of shatter cones, and associated with a positive magnetic field anomaly of ~120 nT amplitude and 3 km wavelength. The latter correlates well with the location of thedeepest uplifted strata, an impact-tilted Proterozoic dolomite layer of the Shaler Supergroup exposed near the center of the structure and intruded by dolerite dykes. Locally, electromagnetic field data unveil a conductive superficial formation which corresponds to an 80-100 m thick sandlayer covering the impact structure. Based on measurements of magnetic properties of rock samples, we model the source of the magnetic anomaly as the magnetic sediments of the Shaler Supergroup combined with a core of uplifted crystalline basement with enhanced magnetization. More classically, the low gravity signature is attributed to a reduction in density measured on the brecciated target rocks and to the isolated sand formations. However, the present-day fractured zone does not extend deeper than ~1 km in our model, indicating a possible 1.5 km of erosionsince the time of impact, about 430 Ma ago

TEXTURAL EVIDENCE FOR IMPACT MELT IN DRILL CORE AT THE HAUGHTON IMPACT STRUCTURE, NUNAVUT

International audienceIgneous textures indicative of rapid cooling of a carbonate-silicate melt have been identified in drill core from the Haughton impact structure

TEXTURAL EVIDENCE FOR IMPACT MELT IN DRILL CORE AT THE HAUGHTON IMPACT STRUCTURE, NUNAVUT

International audienceIgneous textures indicative of rapid cooling of a carbonate-silicate melt have been identified in drill core from the Haughton impact structure

TEXTURAL EVIDENCE FOR IMPACT MELT IN DRILL CORE AT THE HAUGHTON IMPACT STRUCTURE, NUNAVUT

International audienceIgneous textures indicative of rapid cooling of a carbonate-silicate melt have been identified in drill core from the Haughton impact structure