874 research outputs found
Analysis of roles and groups in blogosphere
In the paper different roles of users in social media, taking into
consideration their strength of influence and different degrees of
cooperativeness, are introduced. Such identified roles are used for the
analysis of characteristics of groups of strongly connected entities. The
different classes of groups, considering the distribution of roles of users
belonging to them, are presented and discussed.Comment: 8th International Conference on Computer Recognition Systems, CORES
201
Different Approaches to Community Evolution Prediction in Blogosphere
Predicting the future direction of community evolution is a problem with high
theoretical and practical significance. It allows to determine which
characteristics describing communities have importance from the point of view
of their future behaviour. Knowledge about the probable future career of the
community aids in the decision concerning investing in contact with members of
a given community and carrying out actions to achieve a key position in it. It
also allows to determine effective ways of forming opinions or to protect group
participants against such activities. In the paper, a new approach to group
identification and prediction of future events is presented together with the
comparison to existing method. Performed experiments prove a high quality of
prediction results. Comparison to previous studies shows that using many
measures to describe the group profile, and in consequence as a classifier
input, can improve predictions.Comment: SNAA2013 at ASONAM2013 IEEE Computer Societ
Why business angels reject investment opportunities: Is it personal?
A major focus of research on business angels has examined their decision-making processes and investment criteria. As business angels reject most of the opportunities that they receive, this article explores the reasons informing such decisions. In view of angel heterogeneity, investment opportunities might be expected to be rejected for differing reasons. Two sources of data are used to examine this issue. Face-to-face interviews with 30 business angels in Scotland and Northern Ireland provided information on typical ‘deal killers’. This was complemented by an Internet survey of United Kingdom that attracted responses from 238 UK business angels. The findings confirm that the main reason for rejection relates to the entrepreneur/management team. However, angel characteristics do not explain the number of reasons given for opportunity rejection nor do they predict the reasons for rejecting investment opportunities. This could be related to the increasing trend for business angels to join organised groups which, in turn, leads to the development of a shared repertoire of investment approaches. We suggest the concept of ‘communities-of-practice’ as an explanation for this finding
Brucella spp. of amphibians comprise genomically diverse motile strains competent for replication in macrophages and survival in mammalian hosts
Twenty-one small Gram-negative motile coccobacilli were isolated from 15 systemically diseased African bullfrogs (Pyxicephalus edulis), and were initially identified as Ochrobactrum anthropi by standard microbiological identification systems. Phylogenetic reconstructions using combined molecular analyses and comparative whole genome analysis of the most diverse of the bullfrog strains verified affiliation with the genus Brucella and placed the isolates in a cluster containing B. inopinata and the other non-classical Brucella species but also revealed significant genetic differences within the group. Four representative but molecularly and phenotypically diverse strains were used for in vitro and in vivo infection experiments. All readily multiplied in macrophage-like murine J774-cells, and their overall intramacrophagic growth rate was comparable to that of B. inopinata BO1 and slightly higher than that of B. microti CCM 4915. In the BALB/c murine model of infection these strains replicated in both spleen and liver, but were less efficient than B. suis 1330. Some strains survived in the mammalian host for up to 12 weeks. The heterogeneity of these novel strains hampers a single species description but their phenotypic and genetic features suggest that they represent an evolutionary link between a soil-associated ancestor and the mammalian host-adapted pathogenic Brucella species
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The rate-limiting step for alkane dehydrogenation in zeolite H-ZSM-5.
We have carried out a computational study of protolytic cracking, dehydrogenation, and H/D exchange of ethane, propane, and butane using a cluster model of H-ZSM-5. Our previous work has demonstrated that quantum-chemical techniques can give quantitatively accurate activation energies for alkane cracking in zeolites [1]. Experimental kinetic studies have shown that the apparent activation energies for cracking and H/D exchange decrease with n-alkane chain length, while for dehydrogenation the energies increase [2,3]. Our goal is to study the dependence of the activation energy on the alkane chain length in these reactions and to understand why the dehydrogenation reaction behaves so differently
Spontaneous polarisation of the neutral interface for valence asymmetric coulombic systems
In this paper, we discuss the phenomenon of a spontaneous polarisation of a
neutral hard planar interface for valence asymmetric coulombic systems. Within
a field theoretical description, we account for the existence of non trivial
charge density and electric potential profiles. The analysis of the phenomenon
shows that the effect is related to combinatorics in relation with the
existence of the two independent species cations and anions. This simple and
basic feature is related to the quantum mechanical properties of the system.
The theoretical results are compared with numerical simulations data and are
shown to be in very good agreement, which a fortiori justifies our physical
interpretation.Comment: 12 pages, 11 figure
Brucella melitensis MucR, an orthologue of Sinorhizobium meliloti MucR, is involved in resistance to oxidative, detergent, and saline stresses and cell envelope modifications
Brucella spp. and Sinorhizobium meliloti are alphaproteobacteria that share not only an intracellular lifestyle in their respective hosts, but also a crucial requirement for cell envelope components and their timely regulation for a successful infectious cycle. Here, we report the characterization of Brucella melitensis mucR, which encodes a zinc finger transcriptional regulator that has previously been shown to be involved in cellular and mouse infections at early time points. MucR modulates the surface properties of the bacteria and their resistance to environmental stresses (i.e., oxidative stress, cationic peptide, and detergents). We show that B. melitensis mucR is a functional orthologue of S. meliloti mucR, because it was able to restore the production of succinoglycan in an S. meliloti mucR mutant, as detected by calcofluor staining. Similar to S. meliloti MucR, B. melitensis MucR also represses its own transcription and flagellar gene expression via the flagellar master regulator ftcR. More surprisingly, we demonstrate that MucR regulates a lipid A core modification in B. melitensis. These changes could account for the attenuated virulence of a mucR mutant. These data reinforce the idea that there is a common conserved circuitry between plant symbionts and animal pathogens that regulates the relationship they have with their hosts
Universal Constraints on Low-Energy Flavour Models
It is pointed out that in a general class of flavour models one can identify
certain universally present FCNC operators, induced by the exchange of heavy
flavour messengers. Their coefficients depend on the rotation angles that
connect flavour and fermion mass basis. The lower bounds on the messenger scale
are derived using updated experimental constraints on the FCNC operators. The
obtained bounds are different for different operators and in addition they
depend on the chosen set of rotations. Given the sensitivity expected in the
forthcoming experiments, the present analysis suggests interesting room for
discovering new physics. As the highlights emerge the leptonic processes,
, and
conversion in nuclei.Comment: 18 pages, 3 figures; v2 matches published versio
The Messenger Sector of SUSY Flavour Models and Radiative Breaking of Flavour Universality
The flavour messenger sectors and their impact on the soft SUSY breaking
terms are investigated in SUSY flavour models. In the case when the flavour
scale M is below the SUSY breaking mediation scale M_S, the universality of
soft terms, even if assumed at M_S, is radiatively broken. We estimate this
effect in a broad class of models. In the CKM basis that effect gives flavour
off-diagonal soft masses comparable to the tree-level estimate based on the
flavour symmetry.Comment: 24 pages, 3 figures. v3: minor changes in the text, typos corrected,
version accepted for publication in JHE
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