54 research outputs found

    Conservando el pasado para preservar el futuro: Un modelo de gestión posible

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    The present paper aims to transmit the experience gained in planing, developing and concreting the plan to preserve bibliographic material. It emphasizes the manage of ressources and the utilization of the institutional opportunities present, for the development of such a program

    Environmental factors modulated ancient mitochondrial DnA variability and the prevalence of rheumatic diseases in the Basque country

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    Among the factors that would explain the distribution of mitochondrial lineages in Europe, climate and diseases may have played an important role. A possible explanation lies in the nature of the mitochondrion, in which the energy generation process produces reactive oxygen species that may influence the development of different diseases. The present study is focused on the medieval necropolis of San Miguel de Erenozar (13th-16th centuries, Basque Country), whose inhabitants presented a high prevalence of rheumatic diseases and lived during the Little Ice Age (LIA). Our results indicate a close relationship between rheumatic diseases and mitochondrial haplogroup H, and specifically between spondyloarthropathies and sub-haplogroup H2. One possible explanation may be the climate change that took place in the LIA that favoured those haplogroups that were more energy-efficient, such as haplogroup H, to endure lower temperatures and food shortage. However, it had a biological trade-off: the increased risk of developing rheumatic diseases.This work was supported by the Spanish Ministry of Economy, Industry and Competitiveness (GCL2016-79093/P), and grants from the Basque Government to Research Groups of the Basque University System (IT1138-16) and to Imanol Martin Laza (2014_1_326). We are grateful to the Institutions that granted permission for human remains study, including the Cultural Heritage Department of the Government of the Basque Country and the Archaeology Museum of Bizkaia

    Cómo y por qué desarrollamos e implementamos un sistema que le permitió a nuestros usuarios votar electrónicamente un núcleo básico de revistas

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    Development and implementation of the core collection voting system by the researchers and profesors of the Exact Sciences Faculty of Universidad de Buenos Aires. With the obtained results, number of titles and current coverage so much as the community participation

    Cómo y por qué desarrollamos e implementamos un sistema que le permitió a nuestros usuarios votar electrónicamente un núcleo básico de revistas

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    Development and implementation of the core collection voting system by the researchers and profesors of the Exact Sciences Faculty of Universidad de Buenos Aires. With the obtained results, number of titles and current coverage so much as the community participation

    Development of a UV-C air sterilizer for the control of the air transmission of COVID-19

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    En el contexto de la pandemia por COVID-19, y considerando que existe una transmisión área del virus, que la OMS tardó en reconocer, pero que hoy está comprobado, decidimos desarrollar un Esterilizador de Aire con una combinación específica de Filtros Especiales y el uso de Luz UV-C. Luego del desarrollo del esterilizador (Belerofonte I), se realizaron pruebas biológicas, con Virus, Bacterias, Hongos y Esporas, para ver su efectividad en esterilizar ambientes. Luego de los resultados contundentes obtenidos, y de las pruebas de flujo de aire realizadas en Ingeniería, el equipo se escaló a un tamaño más pequeño, logrando las mismas prestaciones (Belerofonte II). Con el segundo prototipo se repitieron las pruebas, mostrando la misma efectividad. Si bien el desarrollo se enmarca en la pandemia por COVID-19, sería de utilidad a largo plazo, dadas sus prestaciones, para evitar infecciones intrahospitalarias, y que podría ser aplicable a consultorios, transporte público, locales comerciales, entre otros.In the context of the COVID-19 pandemic, and considering that there is an airborne transmission of the virus, which the WHO was slow to recognize, but is now proven, we decided to develop an Air Sterilizer with a specific combination of Special Filters and the use UV-C Light. After the development of the sterilizer (Belerofonte I), biological tests were carried out with Viruses, Bacteria, Fungi and Spores, to see its effectiveness in sterilizing environments. After the strong results obtained, and the air flow tests carried out in Engineering, the equipment was scaled to a smaller size, with the same performance (Belerofonte II). The tests were repeated with the second prototype, showing the same effectiveness. Although the development is a part to fight the COVID-19 pandemic, it would be useful in the long term, given its benefits, to avoid intra-hospital infections, and it could be applicable to clinics, public transport, and commercial premises, among others.Financiamiento: UNLP – Incubadora de Proyectos MinervaSecretaría de Ciencia y Técnic

    Desarrollo de un esterilizador de aire UV-C para el control de la transmisión aérea del COVID-19

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    In the context of the COVID-19 pandemic, and considering that there is an airborne transmission of the virus, which the WHO was slow to recognize, but is now proven, we decided to develop an Air Sterilizer with a specific combination of Special Filters and the use UV-C Light. After the development of the sterilizer (Belerofonte I), biological tests were carried out with Viruses, Bacteria, Fungi and Spores, to see its effectiveness in sterilizing environments. After the strong results obtained, and the air flow tests carried out in Engineering, the equipment was scaled to a smaller size, with the same performance (Belerofonte II). The tests were repeated with the second prototype, showing the same effectiveness. Although the development is a part to fight the COVID-19 pandemic, it would be useful in the long term, given its benefits, to avoid intra-hospital infections, and it could be applicable to clinics, public transport, and commercial premises, among others.En el contexto de la pandemia porCOVID-19, y considerando que existe una transmisión área del virus, que la OMS tardó en reconocer, pero que hoy está comprobado, decidimos desarrollar un Esterilizador de Aire con una combinación específica de Filtros Especiales y el uso de Luz UV-C. Luego del desarrollo del esterilizador (Belerofonte I), se realizaron pruebas biológicas, con Virus, Bacterias, Hongos y Esporas, para ver su efectividad en esterilizar ambientes. Luego de los resultados contundentes obtenidos, y de las pruebas de flujo de aire realizadas en Ingeniería, el equipo se escaló a un tamaño más pequeño, logrando las mismas prestaciones (Belerofonte II). Con el segundo prototipo se repitieron las pruebas, mostrando la misma efectividad. Si bien el desarrollo se enmarca en la pandemia por COVID-19, sería de utilidad a largo plazo, dadas sus prestaciones, para evitar infecciones intrahospitalarias, y que podría ser aplicable a consultorios, transporte público, locales comerciales, entre otros

    Cardiovascular morbidity and associated risk factors in Spanish patients with chronic inflammatory rheumatic diseases attending rheumatology clinics: Baseline data of the CARMA Project

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    Objective To establish the cardiovascular (CV) morbidity and associated risk factors for CV disease (CVD) in Spanish patients with chronic inflammatory rheumatic diseases (CIRD) and unexposed individuals attending rheumatology clinics. Methods Analysis of data from the baseline visit of a 10-year prospective study [CARdiovascular in rheuMAtology (CARMA) project] that includes a cohort of patients with CIRD [rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA)] and another cohort of matched individuals without CIRD attending outpatient rheumatology clinics from 67 hospitals in Spain. Prevalence of CV morbidity, CV risk factors, and systematic coronary risk evaluation (SCORE) assessment were analyzed. Results A total of 2234 patients (775 RA, 738 AS, and 721 PsA) and 677 unexposed subjects were included. Patients had low disease activity at the time of recruitment. PsA patients had more commonly classic CV risk factors and metabolic syndrome features than did the remaining individuals. The prevalence of CVD was higher in RA (10.5%) than in AS (7.6%), PsA (7.2%), and unexposed individuals (6.4%). A multivariate analysis adjusted for the presence of classic CV risk factors and disease duration revealed a positive trend for CVD in RA (OR = 1.58; 95% CI: 0.90–2.76; p = 0.10) and AS (OR = 1.77; 95% CI: 0.96–3.27; p = 0.07). Disease duration in all CIRD groups and functional capacity (HAQ) in RA were associated with an increased risk of CVD (OR = 2.15; 95% CI: 1.29–3.56; p = 0.003). Most patients had a moderate CV risk according to the SCORE charts. Conclusions Despite recent advances in the management of CIRD, incidence of CVD remains increased in Spanish subjects with CIRD attending outpatient rheumatology clinics

    Sociología a pie

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    Unidad Deptal. de Sociología: Metodología y TeoríaFac. de Ciencias de la InformaciónFALSEsubmitte

    Sociología a pie

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    Sociología a pie, pretende difundir contenidos de Sociología, Sociología política y Opinión pública que no se pueden trabajar en el aula, acercándolos también al público general desde espacios públicos para mostrar el carácter abierto de la ciencia
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