64 research outputs found
SPHERE IRDIS and IFS astrometric strategy and calibration
Full text linkWe present the current results of the astrometric characterization of the VLT
planet finder SPHERE over 2 years of on-sky operations. We first describe the
criteria for the selection of the astrometric fields used for calibrating the
science data: binaries, multiple systems, and stellar clusters. The analysis
includes measurements of the pixel scale and the position angle with respect to
the North for both near-infrared subsystems, the camera IRDIS and the integral
field spectrometer IFS, as well as the distortion for the IRDIS camera. The
IRDIS distortion is shown to be dominated by an anamorphism of 0.60+/-0.02%
between the horizontal and vertical directions of the detector, i.e. 6 mas at
1". The anamorphism is produced by the cylindrical mirrors in the common path
structure hence common to all three SPHERE science subsystems (IRDIS, IFS, and
ZIMPOL), except for the relative orientation of their field of view. The
current estimates of the pixel scale and North angle for IRDIS are
12.255+/-0.009 milliarcseconds/pixel for H2 coronagraphic images and
-1.75+/-0.08 deg. Analyses of the IFS data indicate a pixel scale of
7.46+/-0.02 milliarcseconds/pixel and a North angle of -102.18+/-0.13 deg. We
finally discuss plans for providing astrometric calibration to the SPHERE users
outside the instrument consortium.Comment: 12 pages, 6 figures, 3 table
The beta Pictoris system: Setting constraints on the planet and the disk structures at mid-IR wavelengths with NEAR
Get PDF[abridged] We analyzed mid-infrared high-contrast coronagraphic images of the
beta Pictoris system, taking advantage of the NEAR experiment using the
VLT/VISIR instrument. The goal of our analysis is to investigate both the
detection of the planet beta Pictoris b and of the disk features at mid-IR
wavelengths. In addition, by combining several epochs of observation, we expect
to constrain the position of the known clumps and improve our knowledge on the
dynamics of the disk. To evaluate the planet b flux contribution, we extracted
the photometry and compared it to the flux published in the literature. In
addition, we used previous data from T-ReCS and VISIR, to study the evolution
of the position of the southwest clump that was initially observed in the
planetary disk back in 2003. While we did not detect the planet b, we were able
to put constraints on the presence of circumplanetary material, ruling out the
equivalent of a Saturn-like planetary ring around the planet. The disk presents
several noticeable structures, including the known southwest clump. Using a
16-year baseline, sampled with five epochs of observations, we were able to
examine the evolution of the clump: the clump orbits in a Keplerian motion with
an sma of 56.1+-0.4 au. In addition to the known clump, the images clearly show
the presence of a second clump on the northeast side of the disk and fainter
and closer structures that are yet to be confirmed. We found correlations
between the CO clumps detected with ALMA and the mid-IR images. If the
circumplanetary material were located at the Roche radius, the maximum amount
of dust determined from the flux upper limit around beta Pictoris b would
correspond to the mass of an asteroid of 5 km in diameter. Finally, the
Keplerian motion of the southwestern clump is possibly indicative of a
yet-to-be-detected planet or signals the presence of a vortex.Comment: Accepted in Astronomy and Astrophysic
Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients
Get PDFLongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases
Get PDFThe current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our “modern” postwar societies globally characterized by rural-to-urban migration, modernization of agricultural practices, and transportation, climate change, and aging. Evidence suggests that these changes are related to each other, although the social and biological mechanisms as well as their interactions have yet to be uncovered. LongITools, as one of the 9 projects included in the European Human Exposome Network, will tackle this environmental health equation linking multidimensional environmental exposures to the occurrence of cardiovascular and metabolic noncommunicable diseases.</p
Inhibition/activation in bipolar disorder: validation of the Multidimensional Assessment of Thymic States scale (MAThyS)
Get PDFInternational audienceBackgroundOne of the major issues in clinical practice is the accurate differential diagnosis between mixed states and depression, often leading to inappropriate prescriptions of antidepressants in mixed states, and as a consequence, increasing the risk of manic switch and suicide. In order to better define the spectrum of mixed states, it may be useful to develop a dimensional approach. In this context, the MAThyS (Multidimensional Assessment of Thymic States) scale was built to assess activation/inhibition levels in all bipolar mood episodes, and to determine whether a clinical description in terms of activation/inhibition can help better define bipolar states with which both manic and depressive symptoms are associated. The aim of this paper is the validation of the MAThyS scale in 141 bipolar patients in acute states (manic, hypomanic, mixed, or depressive).MethodsThe validation of the MAThyS scale was the primary outcome of this 24-week, phase III, open-label, olanzapine single-arm clinical trial. Principal component, factorial analysis, and Cronbach's coefficient calculation (internal consistency) were performed. Concurrent validity (correlations with 17-item Hamilton Depression Rating Scale [HAMD-17], Hamilton Anxiety Rating Scale [HAMA], and Young Mania Rating Scale [YMRS]) and responsiveness to the clinical intervention were assessed (change in MAThyS scale and effect size) at 6 and 24 weeks.ResultsScree plot of eigenvalues identified a 2-dimension structure ("activation/inhibition level" and "emotional component"). Psychometric properties were good: Cronbach's coefficient was >0.9. Concurrent validity was good with low correlation (−0.19) with the HAMA scale and a higher correlation at baseline with the YMRS (0.72) and HAMD-17(−0.43). As expected, the activation state was predominant in manic, hypomanic, and mixed states while inhibition was predominant in depressive states. MAThyS score improvement was observed (effect size: -0.3 at 6 and 24 weeks).ConclusionsThe MAThyS demonstrated good psychometric properties. The MAThyS scale may help clinicians to better discriminate and follow bipolar episodes, especially the broad spectrum of mixed episodes.Trial registrationClinicalTrials.gov registration identification number: NCT#00259272
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