Proximate and sensory analysis of wheat bread supplemented with Nigella sativa oil and Nigella sativa extract

Wheat is one of the important food crops worldwide while wheat bread is the most commonly consumed form of it in different populations. As Nigella sativa is rich in several phytochemicals that possess disease preventive properties hence, the proximate and sensory analysis of the breads supplemented with Nigella sativa extract and oil have been discussed in this study. Nigella sativa is one of the famous medicinal plants that has been used for treatment of various illnesses in different parts of the world. Compositional analysis revealed that Nigella sativa extract supplemented bread contains 14.75% moisture content, 10.32% crude fat content, 4.40 % ash and 3.55 % crude fiber, 11.89% crude protein and 55.09% Nitrogen Free Extract (NFE). In comparison, analysis of Nigella sativa oil supplemented revealed that it contains 14.23%, moisture content, 10.53% crude fat content, 4.10% ash and 3.20 % crude fiber, 11.79% crude protein and 56.15% NFE. Sensory evaluation was evaluated using 9 points-hedonic scale. Maximum score for overall acceptability was recorded for Nigella sativa extract fortified bread. In the meantime, the requests for wheat-based items with value addition are developing quickly in the previous couple of decades, as customers understood that eating foods with medical advantages is superior to taking medicine. The breads fortified with Nigella sativa will not only meet the consumer demands in terms of sensory attributes but might also aid in improving their health

4D printing roadmap

Four-dimensional (4D) printing is an advanced manufacturing technology that has rapidly emerged as a transformative tool with the capacity to reshape various research domains and industries. Distinguished by its integration of time as a dimension, 4D printing allows objects to dynamically respond to external stimuli, setting it apart from conventional 3D printing. This roadmap has been devised, by contributions of 44 active researchers in this field from 32 affiliations world-wide, to navigate the swiftly evolving landscape of 4D printing, consolidating recent advancements and making them accessible to experts across diverse fields, ranging from biomedicine to aerospace, textiles to electronics. The roadmap’s goal is to empower both experts and enthusiasts, facilitating the exploitation of 4D printing’s transformative potential to create intelligent, adaptive objects that are not only feasible but readily attainable. By addressing current and future challenges and proposing advancements in science and technology, it sets the stage for revolutionary progress in numerous industries, positioning 4D printing as a transformative tool for the future

Costs of services and funding gap of the Bangladesh National Tuberculosis Control Programme 2016-2022: An ingredient based approach.

BackgroundBangladesh National Tuberculosis (TB) Control Programme (NTP) has deployed improved diagnostic technologies which may drive up the programme costs. We aimed to estimate the supply-side costs associated with the delivery of the NTP and the funding gap between the cost of implementation and available funding for the Bangladesh NTP.MethodsAn ingredient-based costing approach was applied using WHO's OneHealth Tool software. We considered 2016, as the base year and projected cost estimates up to 2022 using information on NTP planned activities. Data were collected through consultative meetings with experts and officials/managers, review of documents and databases, and visits to five purposively selected TB healthcare facilities. The estimated costs were compared with the funds allocated to the NTP between 2018 and 2022 to estimate the funding gap.FindingsThe estimated total cost of NTP was US$49.22 million in 2016, which would increase to US$ 146.93 million in 2022. Human resources (41.1%) and medicines and investigations/ supplies (38.0%) were the major two cost components. Unit costs were highest for treating extensively drug-resistant TB at US$7,422.4 in 2016. Between 2018-2022, NTP would incur US$ 536.8 million, which is US$ 235.18 million higher than the current allocation for NTP.ConclusionOur results indicated a funding gap associated with the NTP in each of the years between 2018-2022. Policy planners should advocate for additional funding to ensure smooth delivery of TB services in the upcoming years. The cost estimates of TB services can also be used for planning and budgeting for delivering TB services in similar country contexts

Comparison and effect of plain and calcium fortified yogurt on glycemic responses, anthropometrics and metabolic biomarkers

AbstractMetabolic syndromes including obesity and diabetes are the most common health issues due to insulin resistance, disturbance in glucose homeostasis, lack of exercise, and improper diet. The current study was planned to evaluate the potential effects of regular diet with fortified yogurt on blood glycemia and anthropometric responses. Plain yogurt was procured from the local market, and then it was fortified with calcium. Furthermore, the subsequent effect of fortified yogurt on blood glucose, insulin, and anthropometric measurements was assessed at different time intervals. A total of 40 healthy females and males aged about 20 years with a normal BMI range (20–24.9 kg/m2) were recruited within the Government College University Faisalabad. Participants filled out the habits Performa, stress factors questionnaire, and activity questionnaire. Blood glucose (BG) and visual analogous scale (VAS) performs were also taken in the fasting stage and then assigned treatment was given. After 15, 30, 45, 60, 90, and 120 min intervals VAS and BG estimation was carried out. The results shows that fortified yogurt contained a higher amount of calcium. Likewise, a similar trend was observed for the desire to eat, a feeling of fullness, palatability, physical comfort, and overall acceptability. The results obtained from various analyses were statistically evaluated

A Systematic Review and Meta-Analysis of Fecal Contamination and Inadequate Treatment of Packaged Water

<div><p>Background</p><p>Packaged water products provide an increasingly important source of water for consumption. However, recent studies raise concerns over their safety.</p><p>Objectives</p><p>To assess the microbial safety of packaged water, examine differences between regions, country incomes, packaged water types, and compare packaged water with other water sources.</p><p>Methods</p><p>We performed a systematic review and meta-analysis. Articles published in English, French, Portuguese, Spanish and Turkish, with no date restrictions were identified from online databases and two previous reviews. Studies published before April 2014 that assessed packaged water for the presence of <i>Escherichia coli</i>, thermotolerant or total coliforms were included provided they tested at least ten samples or brands.</p><p>Results</p><p>A total of 170 studies were included in the review. The majority of studies did not detect fecal indicator bacteria in packaged water (78/141). Compared to packaged water from upper-middle and high-income countries, packaged water from low and lower-middle-income countries was 4.6 (95% CI: 2.6–8.1) and 13.6 (95% CI: 6.9–26.7) times more likely to contain fecal indicator bacteria and total coliforms, respectively. Compared to all other packaged water types, water from small bottles was less likely to be contaminated with fecal indicator bacteria (OR = 0.32, 95%CI: 0.17–0.58) and total coliforms (OR = 0.10, 95%CI: 0.05, 0.22). Packaged water was less likely to contain fecal indicator bacteria (OR = 0.35, 95%CI: 0.20, 0.62) compared to other water sources used for consumption.</p><p>Conclusions</p><p>Policymakers and regulators should recognize the potential benefits of packaged water in providing safer water for consumption at and away from home, especially for those who are otherwise unlikely to gain access to a reliable, safe water supply in the near future. To improve the quality of packaged water products they should be integrated into regulatory and monitoring frameworks.</p></div