"MATHEMATICA" EN LA ENSEÑANZA DE MATEMÁTICAS A LOS ESTUDIANTES

The relevance of the topic of the article is due to the process of modernization of higher mathematical education in Russia, which has led to a significant change in curricula and the need to look for ways and forms of training that would allow students to learn the necessary material within the time granted for studying, while obtaining the maximum necessary amount of skills, knowledge, and competencies. The objective of the article is to justify the ways and principles of the development and implementation of new pedagogical and information technologies in the educational process, the organization of professional education of students in technical areas based on the integration of mathematics and computer science. The leading method of the study of this problem is the methodological analysis and subsequent synthesis, which, by analyzing the didactic content of the sections in mathematics and the possibilities of the computer mathematical environment called Mathematica, reveals the necessary methods and ways of developing and using modern computer technologies in the mathematical education of engineering students. It is proved that one of the main tools for implementing the methods for solving the indicated problem should be considered a computer, namely, the mathematical environment called Mathematica, and the basic principles of its systemic implementation in the educational process of the university have been identified. The materials of the article may be useful to teachers of mathematical disciplines of higher educational institutions, the computer programs and pedagogical software products created in Mathematica can serve as models for the development of similar pedagogical software products.  A relevância do tópico do artigo se deve ao processo de modernização do ensino superior de matemática na Rússia, que levou a uma mudança significativa nos currículos e a necessidade de procurar formas e formas de treinamento que permitam aos alunos aprender o necessário material dentro do tempo concedido para o estudo, enquanto obtém a quantidade máxima necessária de habilidades, conhecimentos e competências. O objetivo do artigo é justificar os caminhos e princípios do desenvolvimento e implementação de novas tecnologias pedagógicas e da informação no processo educacional, a organização da formação profissional de estudantes em áreas técnicas baseadas na integração da matemática e da computação. O método principal do estudo desse problema é a análise metodológica e a síntese subsequente, que, analisando o conteúdo didático das seções em matemática e as possibilidades do ambiente matemático computacional chamado Mathematica, revelam os métodos e formas necessários para desenvolver e usar modernas tecnologias de computador na educação matemática de estudantes de engenharia. Está provado que uma das principais ferramentas para implementar os métodos de solução do problema indicado deve ser considerada um computador, a saber, o ambiente matemático chamado Mathematica e os princípios básicos de sua implementação sistêmica no processo educacional da universidade. . Os materiais do artigo podem ser úteis para professores de disciplinas matemáticas de instituições de ensino superior, os programas de computador e os produtos de software pedagógico criados no Mathematica podem servir como modelos para o desenvolvimento de produtos de software pedagógico semelhantes.La relevancia del tema del artículo se debe al proceso de modernización de la educación matemática superior en Rusia, que ha llevado a un cambio significativo en los planes de estudio y la necesidad de buscar formas y formas de capacitación que permitan a los estudiantes aprender lo necesario material dentro del tiempo otorgado para estudiar, mientras se obtiene la cantidad máxima necesaria de habilidades, conocimientos y competencias. El objetivo del artículo es justificar las formas y principios del desarrollo e implementación de nuevas tecnologías pedagógicas y de información en el proceso educativo, la organización de la educación profesional de los estudiantes en áreas técnicas basadas en la integración de las matemáticas y la informática. El método principal para el estudio de este problema es el análisis metodológico y la síntesis posterior, que, al analizar el contenido didáctico de las secciones en matemáticas y las posibilidades del entorno matemático informático llamado Mathematica, revela los métodos y formas necesarios de desarrollar y utilizar tecnologías informáticas modernas en la educación matemática de estudiantes de ingeniería. Está comprobado que una de las principales herramientas para implementar los métodos para resolver el problema indicado debe considerarse una computadora, a saber, el entorno matemático llamado Mathematica, y se han identificado los principios básicos de su implementación sistémica en el proceso educativo de la universidad. . Los materiales del artículo pueden ser útiles para maestros de disciplinas matemáticas de instituciones de educación superior, los programas de computadora y los productos de software pedagógico creados en Mathematica pueden servir como modelos para el desarrollo de productos de software pedagógico similares

Nuclear import of HIV‐1 intracellular reverse transcription complexes is mediated by importin 7.

Human immunodeficiency virus type 1 (HIV‐1), like other lentiviruses, can infect non‐dividing cells. This property depends on the active nuclear import of its intracellular reverse transcription complex (RTC). We have studied nuclear import of purified HIV‐1 RTCs in primary macrophages and found that importin 7, an import receptor for ribosomal proteins and histone H1, is involved in the process. Nuclear import of RTCs requires, in addition, energy and the com ponents of the Ran system. Depletion of importin 7 from cultured cells by small interfering RNA inhibits HIV‐1 infection. These results provide a new insight into the molecular mechanism for HIV‐1 nuclear import and reveal potential targets for therapeutic intervention

Association of morphological traits with lodging resistance in spring barley under the conditions of the Volga-Vyatka region

Background. Lodging has an extremely negative impact on barley yield: grain quality and planting properties are deteriorated, disease incidence increases, and mechanized harvesting becomes difficult, so it is important to find new sources of lodging resistance in barley and use them in crosses and breeding programs to develop non-lodging barley cultivars.Materials and methods. Experimental work was carried out in 2018 and 2019 at Federal Agricultural Science Center of the North-East (FASC North-East), Kirov. Yield structure components and lodging resistance levels were assessed for 29 accessions from the spring barley collection. The study was based on the International COMECON List of Descriptors for the Genus Hordeum L. (subgen. Hordeum) and Methodological Guidelines for the Study and Preservation of the World Collection of Barley and Oats.Results and conclusions. Lodging resistance was observed to have a strong correlation with yield (r = 0.72) and plant height (r = –0.60), and a medium correlation with tillering (r = 0.40) and number of nodal roots at maturation (r = 0.44). No relationship was found between lodging resistance and morphological features of the second lowest internode, which means that selection of non-lodging forms by these criteria will not be effective. Lodging-resistant accessions demonstrated higher yield, tillering, productivity, 1000 grain weight, and a longer and denser ear compared to nonresistant accessions. Accessions combining high yield with lodging resistance and a set of traits promising for breeding were identified: ‘Belgorodsky 100’, ‘Naran’ (k-30892), ‘Kazminsky’ (k-30926), ‘Shchedry’ (k-31046) (Russia); ‘Syabra’ (k-30917), ‘Raider’ (Belarus); ‘Odesssky 115’ (k-29010, Ukraine), ‘Mie’ (k-30379, Estonia), ‘Rodos’ (k-30256, Poland)

Changes of gas metabolism, gas homeostasis and tissue respiration in rats during prolonged hypokinesia

The oxygen uptake and tissue gas homeostasis of restrained albinic rats remained relatively constant during a 60 day experiment. The gas metabolism in some tissues changed, and O2 consumption increased in the liver and decreased in the myocardium. Capacity for physical work was reduced by five times. Hypokinesia for 60 days resulted in a delay in the animals growth

Author's term: what is it? / defining the concept "author's term"

In the article the researchers state that in contemporary Russian terminology there is no concept “author's term” and no author’s term definition. Traditionally it has been accepted that the author's term is a term with a reliably known authorship, or a term named after the discoverer of a scientific phenomenon. The researchers consider this approach to be erroneous and suggest that the author's term exists only within the author’s original scientific hypothesis. As this hypothesis is described by the system of interrelated concepts and terms, so there is no isolated author’s term. The researchers offer their own definition of the author's term. The author’s term is a special sign created within the framework of a unique scientific theory, an element of the system of concepts interconnected with other terms and concepts of original hypothesis, referred by the speakers of the language for specific purposes to a specific author's idea, representing scientific picture of the world which is not generally accepted

The investigation of the time characteristic of local polar inhomogeneities in paraelectric phase in relaxors and ferroelectric crystals: on the example of SrxBa1-xNb2O6 crystals with different chemical composition

The reported study was funded by RFBR according to the research projects No. 18-02-00399 and State assignment No AAAAA17-117052410033-9. The experiments were performed in the multiple-access center “High-Resolution Spectroscopy of Gases and Condensed Matter” in IA&E SBRAS (Novosibirsk, Russia)

Manifestation of local polar regions in spectroscopic investigations in ferroelectrics and relaxors

The reported study was funded by RFBR according to the research project 18-02-00399 and State assignment No AAAA-A17-117052410033-9. Experiments were performed in the multiple-access center “High-Resolution Spectroscopy of Gases and Condensed Matter” in IA&E SBRAS (Novosibirsk, Russia)

The Ecdysone receptor constrains wingless expression to pattern cell cycle across the Drosophila wing margin in a cyclin B-dependent manner

Background: Ecdysone triggers transcriptional changes via the ecdysone receptor (EcR) to coordinate developmental programs of apoptosis, cell cycle and differentiation. Data suggests EcR affects cell cycle gene expression indirectly and here we identify Wingless as an intermediary factor linking EcR to cell cycle. Results: We demonstrate EcR patterns cell cycle across the presumptive Drosophila wing margin by constraining wg transcription to modulate CycB expression, but not the previously identified Wg-targets dMyc or Stg. Furthermore co-knockdown of Wg restores CycB patterning in EcR knockdown clones. Wg is not a direct target of EcR, rather we demonstrate that repression of Wg by EcR is likely mediated by direct interaction between the EcR-responsive zinc finger transcription factor Crol and the wg promoter. Conclusions: Thus we elucidate a critical mechanism potentially connecting ecdysone with patterning signals to ensure correct timing of cell cycle exit and differentiation during margin wing development