287 research outputs found

    Boas práticas em governança digital : mapeamento e análise dos aplicativos do Governo do Paraná

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    Orientador: Prof. Dr. Sérgio Soares BragaDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Humanas, Programa de Pós-Graduação em Ciência Política. Defesa : Curitiba, 22/12/2020Inclui referências: p.76-82Resumo: O objetivo desta pesquisa é fazer um estudo experiências de governança digital no Paraná, com destaque para o uso de aplicativos e da inteligência artificial na gestão do Governador Ratinho Júnior, entre 2019 e 2020. Para tanto, efetuaremos um estudo exploratório de 26 aplicativos usados pelo governo do Paraná entre 2012 e 2020 desenvolvidos pela Celepar no contexto do Projeto Piá de uso da Inteligência Artificial aplicada ao governo eletrônico. Para isso, a partir da análise do estudo sobre aplicativos no contexto da governança digital, definimos alguns critérios para a avaliação do uso dos aplicativos de governo móvel pelo estado do Paraná. Como metodologia, além de entrevista com gestores envolvidos na implementação dos projetos, a análise de quatro dimensões básicas dos aplicativos: grau de sucesso e permanência; difusão e número de instalações; avaliação dos usuários e responsividade. A partir da análise dessas quatro dimensões elaboramos um índice que nos permite identificar algumas boas práticas de governança digital mediante uso de aplicativos que serão analisadas brevemente. Por fim, será resumida as entrevistas feitas com os gestores a fim de identificar a concepção por trás do uso de governo móvel e inteligência artificial pelo governo do Paraná. Palavras-chave: Governança Digital; governo Móvel; Aplicativos; Inteligência Artificial; Boas Práticas.Abstract: The objective of this research is to make a study of digital governance experiences in Paraná, with emphasis on the use of applications and artificial intelligence in the management of Governador Ratinho Júnior, between 2019 and 2020. Therefore, we will carry out an exploratory study of 26 applications used by government of Paraná between 2012 and 2020 developed by Celepar in the context of the Piá Project for the use of Artificial Intelligence applied to electronic government. For this, from the analysis of the study on applications in the context of digital governance, we defined some criteria for the evaluation of the use of mobile government applications by the state of Paraná. As a methodology, in addition to interviewing managers involved in the implementation of the projects, the analysis of four basic dimensions of the applications: degree of success and permanence; diffusion and number of installations; user evaluation and responsiveness. Based on the analysis of these four dimensions, we have developed an index that allows us to identify some good practices of digital governance through the use of applications that will be analyzed shortly. Finally, the interviews with managers will be summarized in order to identify the conception behind the use of mobile government and artificial intelligence by the government of Paraná. Keywords: Digital Governance; Mobile Government; Applications; Artificial intelligence; Best Practices

    Distribuição espacial do bicho-mineiro, Leucoptera coffeella (Guér.-Ménev., 1942)(Lepidoptera: Lyonetiidae), e vespas (Hymenoptera: vespidae) em cafezal (Coffea arabica L.) orgânico em formação.

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    O bicho-mineiro do cafeeiro [Leucoptera coffeella (Guér.-Mènev., 1942).] é uma das maiores pragas dos cafezais, acarretando perdas de até 50% na produção. O conhecimento da distribuição espacial dessa praga e das vespas (Hymenoptera: Vespidae), seus predadores, é muito importante para seu melhor manejo em plantações de café orgânico. Neste trabalho foi estudado um cafezal orgânico em formação no seu terceiro ano de implantação. Foram utilizados os índices de Fisher e Morisita para caracterizar a distribuição espacial do numero de folhas minadas, numero de minas novas, número de minas predadas e número de vespas. Os intervalos de confiança para os índices foram calculados utilizando o método bootstrap. Os índices não conseguiram identificar claramente um padrão espacial para as variáveis no período investigado

    Análise da variabilidade espacial da ocorrência do bicho-mineiro [Leucoptera coffeella, (GUÉR.-MÈNEV., 1942)] (Lepidoptera: Lyonetiidae) em cafezal (Coffea arábica, L.) orgânico em formação.

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    Um dos desafios na produção orgânica de café é o controle de pragas sem o uso de pesticidas. Uma das pragas mais prejudiciais é o bicho-mineiro (Leucoptera coffeella), que pode causar severos danos aos cafeeiros, com perdas que podem alcançar 50% da produção total. Compreender a distribuição espacial do bicho-mineiro pode ser importante no contexto do controle biológico da praga. O objetivo deste trabalho foi caracterizar o relacionamento entre a presença do bicho-mineiro e a localização do cafeeiro (Coffea arabica) em um cultivo orgânico no segundo ano de sua implantação. Foi usado o semivariograma como uma ferramenta para a determinação do grau de dependência espacial do bicho-mineiro. Pelos resultados obtidos, podemos afirmar que a ocorrência do bicho-mineiro apresenta autocorrelação espacial até 30 metros

    Schistosomal appendicitis: Case series and systematic literature review

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    Background Globally, schistosomiasis affects at least 240 million people each year with a high proportion of cases in sub-Saharan Africa. The infection presents a wide range of symptoms mainly at the gastrointestinal and urogenital level. Cases of schistosomiasis-related appendicitis are seldom reported. The aim of the present study is to identify the prevalence of schistosomiasis-related appendicitis in Beira, Mozambique and compare to global prevalence. Methods We retrospectively reviewed all cases of appendicitis recorded from January 2017 to March 2020 at a single pathology department located in Beira in order to assess the prevalence of schistosomiasis. Moreover, we performed a systematic review on the prevalence of schistosomiasis-related appendicitis in all countries. Findings A total of 145 appendicitis cases in Beira showed a 13.1% prevalence of schistosomal-related appendicitis. The mean age of patients was 29.1 years, and 14 (73.7%) were male. The systematic review identified 20 studies with 34,790 inpatientsAUwith: schistosomiasis-related appendicitis with a global prevalence of 1.31% (95% confidence interval (CI): 0.72 to PerPLOSstyle; sufferingfrom2.06); a high heterogeneity (I2 = 96.0%) was observed. Studies carried out in Africa reported a significantly higher prevalence of schistosomiasis-related appendicitis (2.75%; 95% CI: 1.28 to 4.68) than those in Middle East (0.49%; 95% CI: 0.18 to 0.95) (p for interaction < 0.0001). Conclusions Schistosomiasis infection should be considered as possible cause of appendicitis not only in endemic areas but also in developed countries. Considering that prevention is the best way to control the infection, more efforts should be put in place in order to increase the prevention coverage and avoid the cascading implications for health. This is even more so important in this Coronavirus Disease 2019AU(COVID-19): PleasenotethatCOVIDera where the majority19hasbeendefinedasCoof attention and funds are used to fight the pandemic

    Análise temporal do preço do café pago ao produtor pela cooperativa regional de cafeicultores em Guaxupé (Cooxupé).

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    A produção de café no Brasil é considerada uma tradição de mais de dois séculos. Tendo em vista a importância da cafeicultura para o desenvolvimento econômico e social dos estados produtores, o objetivo desse trabalho foi ajustar um modelo capaz de descrever o comportamento da série de preço do café, da cooperativa Cooxupé, no período de janeiro de 1979 a dezembro de 2005, utilizando técnicas de séries temporais. Buscando caracterizar as causas mais importantes da crise, o modelo ARIMA com intervenções foi o que se ajustou melhor aos dados

    Dissecting T Cell Contraction In Vivo Using a Genetically Encoded Reporter of Apoptosis

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    SummaryContraction is a critical phase of immunity whereby the vast majority of effector T cells die by apoptosis, sparing a population of long-lived memory cells. Where, when, and why contraction occurs has been difficult to address directly due in large part to the rapid clearance of apoptotic T cells in vivo. To circumvent this issue, we introduced a genetically encoded reporter for caspase-3 activity into naive T cells to identify cells entering the contraction phase. Using two-photon imaging, we found that caspase-3 activity in T cells was maximal at the peak of the response and was associated with loss of motility followed minutes later by cell death. We demonstrated that contraction is a widespread process occurring uniformly in all organs tested and targeting phenotypically diverse T cells. Importantly, we identified a critical window of time during which antigen encounters act to antagonize T cell apoptosis, supporting a causal link between antigen clearance and T cell contraction. Our results offer insight into a poorly explored phase of immunity and provide a versatile methodology to study apoptosis during the development or function of a variety of immune cells in vivo

    Ethylene biosynthesis and perception during ripening of loquat fruit (Eriobotrya japonica Lindl.)

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    [EN] In order to gain insights into the controversial ripening behavior of loquat fruits, in the present study we have analyzed the expression of three genes related to ethylene biosynthesis (ACS1, ACO1 and ACO2), two ethylene receptors (ERS1a and ERS1b), one signal transduction component (CTR1) and one transcription factor (EIL1) in peel and pulp of loquat fruit during natural ripening and also in fruits treated with ethylene (10 mu LL-1) and 1-MCP (10 mu LL-1), an ethylene action inhibitor. In fruits attached to or detached from the tree, a slight increase in ethylene production was detected at the yellow stage, but the respiration rate declined progressively during ripening. Accumulation of transcripts of ethylene biosynthetic genes did not correlate with changes in ethylene production, since the maximum accumulation of ACS1 and ACO1 mRNA was detected in fully coloured fruits. Expression of ethylene receptor and signaling genes followed a different pattern in peel and pulp tissues. After fruit detachment and incubation at 20 degrees C for up to 6 days, ACS1 mRNA slightly increased, ACO1 experienced a substantial increment and ACO2 declined. In the peel, these changes were advanced by exogenous ethylene and partially inhibited by 1-MCP. In the pulp, 1-MCP repressed most of the changes in the expression of biosynthetic genes, while ethylene had almost no effects. Expression of ethylene perception and signaling genes was barely affected by ethylene or 1-MCP. Collectively, a differential transcriptional regulation of ethylene biosynthetic genes operates in peel and pulp, and support the notion of non-climacteric ripening in loquat fruits. Ethylene action, however, appears to be required to sustain or maintain the expression of specific genes. (C) 2016 Published by Elsevier GmbH.Enriqueta Alos was recipient of a post-doctoral contract JAE-DocCSIC (Fondo Social Europeo). The financial support of the researchgrants FP7-PEOPLE-2011-CIG-2011-303652 (Marie Curie Actions, European Union), AGL-2009-11558 and AGL-2012-34573 (Ministerio Economia y Competitividad, Spain), GV/2012/036 (Generalitat Valenciana, Spain) and PROMETEOII 2014/27 (Generalitat Valenciana) is gratefully acknowledged.Alós, E.; Martinez Fuentes, A.; Reig Valor, C.; Mesejo Conejos, C.; Rodrigo, M.; Agustí Fonfría, M.; Zacarias, L. (2017). Ethylene biosynthesis and perception during ripening of loquat fruit (Eriobotrya japonica Lindl.). Journal of Plant Physiology. 210:64-71. https://doi.org/10.1016/j.jplph.2016.12.008S647121

    Sex differences in stress reactivity, brain morphology, and oxytocin in the hypothalamus of the gray short-tailed opossum (Monodelphis domestica)

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    Understanding the effects of stress on behavior and cognition is important due to its impact on mental health and wellbeing (Schneiderman et al. 2005). Translational animal research can contribute to the development of new treatments that can improve therapeutic outcomes and our understanding of the neurobiology of stress. In the present study, we complement behavioral stress reactivity with immunohistochemical localization of oxytocin in the hypothalamus, a neuropeptide that regulates stress (Neumann & Slattery, 2016). Oxytocin has potential therapeutic use for mental health disorders (Neumann & Slattery, 2016), and the effects of oxytocin seem to be sexually dimorphic (Love, 2018). Using the Monodelphis Domestica, we examined biological sex differences in brain and behavior and hypothesized that there would be sexually dimorphic expression of oxytocin in the hypothalamus of the Monodelphis brain. Open field tests were used to investigate stress in the Monodelphis (4 females, 4 males), their exploratory behavior was recorded and quantified using AnyMaze software, and data were analyzed with SPSS software. Immunohistochemistry was used to study oxytocin expression in the paraventricular nucleus (PVN) of the hypothalamus and the supraoptic nucleus (SON) (Love, 2018). Preliminary results indicate that there is a sex difference in stress reactivity in the Monodelphis Domestica; females exhibit higher mobility duration than males. The preliminary results from our pilot immunohistochemistry study demonstrated that oxytocin expression is present in both the PVN and SON areas. Future studies will explore sexual dimorphisms in this species, including sex differences in the expression of oxytocin in the Monodelphis brain. In conclusion, the present study contributes to our understanding of stress in the Monodelphis, and we observed that oxytocin expression in the Monodelphis model is not as extensive as it is in rodents. Findings will contribute to treatment research, which can improve therapeutic outcomes for individuals with stress-related mental disorders
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