830 research outputs found
Multi-variable translation equation which arises from homothety
In many regular cases, there exists a (properly defined) limit of iterations
of a function in several real variables, and this limit satisfies the
functional equation (1-z)f(x)=f(f(xz)(1-z)/z); here z is a scalar and x is a
vector. This is a special case of a well-known translation equation. In this
paper we present a complete solution to this functional equation in case f is a
continuous function on a single point compactification of a 2-dimensional real
vector space. It appears that, up to conjugation by a homogeneous continuous
function, there are exactly four solutions. Further, in a 1-dimensional case we
present a solution with no regularity assumptions on f.Comment: 15 page
Coherent resonant tunneling in ac fields
We have analyzed the tunneling transmission probability and electronic
current density through resonant heterostructures in the presence of an
external electromagnetic field. In this work, we compare two different models
for a double barrier : In the first case the effect of the external field is
taken into account by spatially dependent AC voltages and in the second one the
electromagnetic field is described in terms of a photon field that irradiates
homogeneously the whole sample. While in the first description the tunneling
takes place mainly through photo sidebands in the case of homogeneous
illumination the main effective tunneling channels correspond to the coupling
between different electronic states due to photon absorption and emission. The
difference of tunneling mechanisms between these configurations is strongly
reflected in the transmission and current density which present very different
features in both cases. In order to analyze these effects we have obtained,
within the Transfer Hamiltonian framework, a general expression for the
transition probability for coherent resonant tunneling in terms of the Green's
function of the system.Comment: 16 pages,Figures available upon request,to appear in Phys.Rev B (15
April 1996
Subnuclear localization, rates and effectiveness of UVC-induced unscheduled DNA synthesis visualized by fluorescence widefield, confocal and super-resolution microscopy
Unscheduled DNA synthesis (UDS) is the final stage of the process of repair of DNA lesions induced by UVC. We detected UDS using a DNA precursor, 5-ethynyl-2′-deoxyuridine (EdU). Using wide-field, confocal and super-resolution fluorescence microscopy and normal human fibroblasts, derived from healthy subjects, we demonstrate that the sub-nuclear pattern of UDS detected via incorporation of EdU is different from that when BrdU is used as DNA precursor. EdU incorporation occurs evenly throughout chromatin, as opposed to just a few small and large repair foci detected by BrdU. We attribute this difference to the fact that BrdU antibody is of much larger size than EdU, and its accessibility to the incorporated precursor requires the presence of denatured sections of DNA. It appears that under the standard conditions of immunocytochemical detection of BrdU only fragments of DNA of various length are being denatured. We argue that, compared with BrdU, the UDS pattern visualized by EdU constitutes a more faithful representation of sub-nuclear distribution of the final stage of nucleotide excision repair induced by UVC. Using the optimized integrated EdU detection procedure we also measured the relative amount of the DNA precursor incorporated by cells during UDS following exposure to various doses of UVC. Also described is the high degree of heterogeneity in terms of the UVC-induced EdU incorporation per cell, presumably reflecting various DNA repair efficiencies or differences in the level of endogenous dT competing with EdU within a population of normal human fibroblasts
Impact of CD14 Polymorphisms on Anti-Apolipoprotein A-1 IgG-Related Coronary Artery Disease Prediction in the General Population.
We aimed to determine whether autoantibodies against apoA-1 (apolipoprotein A-1; anti-apoA-1 IgG) predict incident coronary artery disease (CAD), defined as adjudicated incident myocardial infarction, angina, percutaneous coronary revascularization, or bypass grafting, in the general population. We further investigated whether this association is modulated by a functional CD14 receptor single nucleotide polymorphism.
In a prospectively studied, population-based cohort of 5220 subjects (mean age 52.6±10.7 years, 47.4% males), followed over a median period of 5.6 years, subjects positive versus negative for anti-apoA-1 IgG presented a total CAD rate of 3.9% versus 2.8% (P=0.077) and a nonfatal CAD rate of 3.6% versus 2.3% (P=0.018), respectively. After multivariate adjustment for established cardiovascular risk factors, the hazard ratios of anti-apoA-1 IgG for total and nonfatal CAD were: hazard ratio=1.36 (95% confidence interval, 0.94-1.97; P=0.105) and hazard ratio=1.53 (95% confidence interval, 1.03-2.26; P=0.034), respectively. In subjects with available genetic data for the C260T rs2569190 single nucleotide polymorphism in the CD14 receptor gene (n=4247), we observed a significant interaction between anti-apoA-1 IgG and rs2569190 allele status with regards to CAD risk, with anti-apoA-1 IgG conferring the highest risk for total and nonfatal CAD in non-TT carriers, whereas being associated with the lowest risk for total and nonfatal CAD in TT homozygotes (P for interaction =0.011 and P for interaction =0.033, respectively).
Anti-apoA-1 IgG are independent predictors of nonfatal incident CAD in the general population. The strength of this association is dependent on a functional polymorphism of the CD14 receptor gene, a finding suggesting a gene-autoantibody interaction for the development of CAD
The Effect of Processing Route on Properties of HfNbTaTiZr High Entropy Alloy
High entropy alloys (HEA) have been one of the most attractive groups of materials for researchers in the last several years. Since HEAs are potential candidates for many (e.g., refractory, cryogenic, medical) applications, their properties are studied intensively. The most frequent method of HEA synthesis is arc or induction melting. Powder metallurgy is a perspective technique of alloy synthesis and therefore in this work the possibilities of synthesis of HfNbTaTiZr HEA from powders were studied. Blended elemental powders were sintered, hot isostatically pressed, and subsequently swaged using a special technique of swaging where the sample is enveloped by a titanium alloy. This method does not result in a full density alloy due to cracking during swaging. Spark plasma sintering (SPS) of mechanically alloyed powders resulted in a fully dense but brittle specimen. The most promising result was obtained by SPS treatment of gas atomized powder with low oxygen content. The microstructure of HfNbTaTiZr specimen prepared this way can be refined by high pressure torsion deformation resulting in a high hardness of 410 HV10 and very fine microstructure with grain size well below 500 nm.11Ysciescopu
Low Temperature Precursor Route for Highly Efficient Spherically Shaped LED-Phosphors M2Si5N8:Eu2+ (M = Eu, Sr, Ba)
The highly efficient nitridosilicate phosphors M2Si5N8 (M = Sr, Ba, Eu) for phosphor-converted pc-LEDs were synthesized at low temperatures using a novel precursor route involving metal amides M(NH2)2. These precursors have been synthesized by dissolution of the respective metals in supercritical ammonia at 150°C and 300 bar. The thermal behavior and decomposition process of the amides were investigated with temperature programmed powder X-ray diffractometry and thermoanalytical measurements (DTA/TG). These investigations rendered the amides as suitable intermediates for reaction with silicon diimide (Si(NH)2). Thus, the desired nitridosilicate phosphors were obtained at relatively low temperatures around 1150−1400°C which is approximately 300°C lower compared to common synthetic approaches starting from metals or oxides. The influence of the thermal treatment on the phosphor morphology has been studied extensively. The accessibility of spherical phosphor particles represents another striking feature of this route since it improves light extraction from the crystallites due to decreasing light guiding and decreasing re-absorption inside the phosphor particle. The synthesized luminescent materials M2Si5N8:Eu2+ (M = Sr, Ba) exhibit quantum efficiencies and emission band widths (FWHM 70−90 nm) comparable to standard phosphor powders. Employment of Eu(NH2)2 as dopant reagent for synthesis of Ba2Si5N8:Eu2+ proved favorable for the formation of spherical crystallites compared to doping with Eu metal, halides, or oxide
Applications of Direct Injection Soft Chemical Ionisation-Mass Spectrometry for the Detection of Pre-blast Smokeless Powder Organic Additives
Analysis of smokeless powders is of interest from forensics and security perspectives. This article reports the detection of smokeless powder organic additives (in their pre-detonation condition), namely the stabiliser diphenylamine and its derivatives 2-nitrodiphenylamine and 4-nitrodiphenylamine, and the additives (used both as stabilisers and plasticisers) methyl centralite and ethyl centralite, by means of swab sampling followed by thermal desorption and direct injection soft chemical ionisation-mass spectrometry. Investigations on the product ions resulting from the reactions of the reagent ions H3O+ and O2+ with additives as a function of reduced electric field are reported. The method was comprehensively evaluated in terms of linearity, sensitivity and precision. For H3O+, the limits of detection (LoD) are in the range of 41-88 pg of additive, for which the accuracy varied between 1.5 and 3.2%, precision varied between 3.7 and 7.3% and linearity showed R20.9991. For O2+, LoD are in the range of 72 to 1.4 ng, with an accuracy of between 2.8 and 4.9% and a precision between 4.5 and 8.6% and R20.9914. The validated methodology was applied to the analysis of commercial pre-blast gun powders from different manufacturers.(VLID)4826148Accepted versio
Multifractal properties of power-law time sequences; application to ricepiles
We study the properties of time sequences extracted from a self-organized
critical system, within the framework of the mathematical multifractal
analysis. To this end, we propose a fixed-mass algorithm, well suited to deal
with highly inhomogeneous one dimensional multifractal measures. We find that
the fixed mass (dual) spectrum of generalized dimensions depends on both the
system size L and the length N of the sequence considered, being however stable
when these two parameters are kept fixed. A finite-size scaling relation is
proposed, allowing us to define a renormalized spectrum, independent of size
effects.We interpret our results as an evidence of extremely long-range
correlations induced in the sequence by the criticality of the systemComment: 12 pages, RevTex, includes 9 PS figures, Phys. Rev. E (in press
New interpretation of variational principles for gauge theories. I. Cyclic coordinate alternative to ADM split
I show how there is an ambiguity in how one treats auxiliary variables in
gauge theories including general relativity cast as 3 + 1 geometrodynamics.
Auxiliary variables may be treated pre-variationally as multiplier coordinates
or as the velocities corresponding to cyclic coordinates. The latter treatment
works through the physical meaninglessness of auxiliary variables' values
applying also to the end points (or end spatial hypersurfaces) of the
variation, so that these are free rather than fixed. [This is also known as
variation with natural boundary conditions.] Further principles of dynamics
workings such as Routhian reduction and the Dirac procedure are shown to have
parallel counterparts for this new formalism. One advantage of the new scheme
is that the corresponding actions are more manifestly relational. While the
electric potential is usually regarded as a multiplier coordinate and Arnowitt,
Deser and Misner have regarded the lapse and shift likewise, this paper's
scheme considers new {\it flux}, {\it instant} and {\it grid} variables whose
corresponding velocities are, respectively, the abovementioned previously used
variables. This paper's way of thinking about gauge theory furthermore admits
interesting generalizations, which shall be provided in a second paper.Comment: 11 page
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